The antiproliferative potential of fungi associated with coral and algae collected from a Veracruz Reef System, Gulf of Mexico
ABSTRACT Coral reefs are ecosystems with great biodiversity and architectural complexity. Among these, marine fungi constitute one of the least studied groups, despite being potentially an inexhaustible source of bioactive metabolites. For this reason, in this research, we evaluate the antiprolifera...
Guardado en:
| Autores principales: | , , , , , , |
|---|---|
| Lenguaje: | English |
| Publicado: |
Pontificia Universidad Católica de Valparaíso. Facultad de Recursos Naturales. Escuela de Ciencias del Mar
2021
|
| Materias: | |
| Acceso en línea: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-560X2021000500843 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:scielo:S0718-560X2021000500843 |
|---|---|
| record_format |
dspace |
| spelling |
oai:scielo:S0718-560X20210005008432021-11-25The antiproliferative potential of fungi associated with coral and algae collected from a Veracruz Reef System, Gulf of MexicoEspinoza,CésarHerrera-García,Carlos D.Espinosa-García,VictoriaCouttolenc,AlanAndrade-Torres,AntonioPadrón,José M.Trigos,Ángel Nigrospora Pestalotiopsis Cladosporium Ochroconis antiproliferative effect marine fungi ABSTRACT Coral reefs are ecosystems with great biodiversity and architectural complexity. Among these, marine fungi constitute one of the least studied groups, despite being potentially an inexhaustible source of bioactive metabolites. For this reason, in this research, we evaluate the antiproliferative activity of 52 fungal strains associated with marine organisms such as algae and coral collected from four islands located in the National Park Sistema Arrecifal Veracruzano, Mexico. One hundred four chloroform:methanol extracts corresponding to the culture broth, and biomass produced from each fungal strain was obtained from these. Subsequently, they were evaluated against six human solid tumor cell lines (HBL-100, HeLa, SW1573, T-47D, WiDr, and A549). The outcome was that six extracts showed activity against at least one cancer cell line. The identity of these fungi corresponded to the genera Nigrospora, Pestalotiopsis, Cladosporium, and Ochroconis according to their morphological and molecular analysis. In this sense, the strain found to have the highest antiproliferative potential [GI50 (μg mL-1) 4.6, 2.5, 8.0, 5.6, 52.0, 4.0] grouped phylogenetically with a species of Nigrospora sp. The preceding confirms that ecosystems provide.info:eu-repo/semantics/openAccessPontificia Universidad Católica de Valparaíso. Facultad de Recursos Naturales. Escuela de Ciencias del MarLatin american journal of aquatic research v.49 n.5 20212021-11-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-560X2021000500843en10.3856/vol49-issue5-fulltext-2704 |
| institution |
Scielo Chile |
| collection |
Scielo Chile |
| language |
English |
| topic |
Nigrospora Pestalotiopsis Cladosporium Ochroconis antiproliferative effect marine fungi |
| spellingShingle |
Nigrospora Pestalotiopsis Cladosporium Ochroconis antiproliferative effect marine fungi Espinoza,César Herrera-García,Carlos D. Espinosa-García,Victoria Couttolenc,Alan Andrade-Torres,Antonio Padrón,José M. Trigos,Ángel The antiproliferative potential of fungi associated with coral and algae collected from a Veracruz Reef System, Gulf of Mexico |
| description |
ABSTRACT Coral reefs are ecosystems with great biodiversity and architectural complexity. Among these, marine fungi constitute one of the least studied groups, despite being potentially an inexhaustible source of bioactive metabolites. For this reason, in this research, we evaluate the antiproliferative activity of 52 fungal strains associated with marine organisms such as algae and coral collected from four islands located in the National Park Sistema Arrecifal Veracruzano, Mexico. One hundred four chloroform:methanol extracts corresponding to the culture broth, and biomass produced from each fungal strain was obtained from these. Subsequently, they were evaluated against six human solid tumor cell lines (HBL-100, HeLa, SW1573, T-47D, WiDr, and A549). The outcome was that six extracts showed activity against at least one cancer cell line. The identity of these fungi corresponded to the genera Nigrospora, Pestalotiopsis, Cladosporium, and Ochroconis according to their morphological and molecular analysis. In this sense, the strain found to have the highest antiproliferative potential [GI50 (μg mL-1) 4.6, 2.5, 8.0, 5.6, 52.0, 4.0] grouped phylogenetically with a species of Nigrospora sp. The preceding confirms that ecosystems provide. |
| author |
Espinoza,César Herrera-García,Carlos D. Espinosa-García,Victoria Couttolenc,Alan Andrade-Torres,Antonio Padrón,José M. Trigos,Ángel |
| author_facet |
Espinoza,César Herrera-García,Carlos D. Espinosa-García,Victoria Couttolenc,Alan Andrade-Torres,Antonio Padrón,José M. Trigos,Ángel |
| author_sort |
Espinoza,César |
| title |
The antiproliferative potential of fungi associated with coral and algae collected from a Veracruz Reef System, Gulf of Mexico |
| title_short |
The antiproliferative potential of fungi associated with coral and algae collected from a Veracruz Reef System, Gulf of Mexico |
| title_full |
The antiproliferative potential of fungi associated with coral and algae collected from a Veracruz Reef System, Gulf of Mexico |
| title_fullStr |
The antiproliferative potential of fungi associated with coral and algae collected from a Veracruz Reef System, Gulf of Mexico |
| title_full_unstemmed |
The antiproliferative potential of fungi associated with coral and algae collected from a Veracruz Reef System, Gulf of Mexico |
| title_sort |
antiproliferative potential of fungi associated with coral and algae collected from a veracruz reef system, gulf of mexico |
| publisher |
Pontificia Universidad Católica de Valparaíso. Facultad de Recursos Naturales. Escuela de Ciencias del Mar |
| publishDate |
2021 |
| url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-560X2021000500843 |
| work_keys_str_mv |
AT espinozacesar theantiproliferativepotentialoffungiassociatedwithcoralandalgaecollectedfromaveracruzreefsystemgulfofmexico AT herreragarciacarlosd theantiproliferativepotentialoffungiassociatedwithcoralandalgaecollectedfromaveracruzreefsystemgulfofmexico AT espinosagarciavictoria theantiproliferativepotentialoffungiassociatedwithcoralandalgaecollectedfromaveracruzreefsystemgulfofmexico AT couttolencalan theantiproliferativepotentialoffungiassociatedwithcoralandalgaecollectedfromaveracruzreefsystemgulfofmexico AT andradetorresantonio theantiproliferativepotentialoffungiassociatedwithcoralandalgaecollectedfromaveracruzreefsystemgulfofmexico AT padronjosem theantiproliferativepotentialoffungiassociatedwithcoralandalgaecollectedfromaveracruzreefsystemgulfofmexico AT trigosangel theantiproliferativepotentialoffungiassociatedwithcoralandalgaecollectedfromaveracruzreefsystemgulfofmexico AT espinozacesar antiproliferativepotentialoffungiassociatedwithcoralandalgaecollectedfromaveracruzreefsystemgulfofmexico AT herreragarciacarlosd antiproliferativepotentialoffungiassociatedwithcoralandalgaecollectedfromaveracruzreefsystemgulfofmexico AT espinosagarciavictoria antiproliferativepotentialoffungiassociatedwithcoralandalgaecollectedfromaveracruzreefsystemgulfofmexico AT couttolencalan antiproliferativepotentialoffungiassociatedwithcoralandalgaecollectedfromaveracruzreefsystemgulfofmexico AT andradetorresantonio antiproliferativepotentialoffungiassociatedwithcoralandalgaecollectedfromaveracruzreefsystemgulfofmexico AT padronjosem antiproliferativepotentialoffungiassociatedwithcoralandalgaecollectedfromaveracruzreefsystemgulfofmexico AT trigosangel antiproliferativepotentialoffungiassociatedwithcoralandalgaecollectedfromaveracruzreefsystemgulfofmexico |
| _version_ |
1718324305068032000 |