Enfermedad cerebrovascular y estatinas
Summary: Cerebrovascular disease is one of the leading causes of death in Chile. Its main manifestation, CVA, is most frequent in elderly subjects. Approximately 70% of CVA recognize an ischemic origin, the rest corresponds to intracerebral bleeding episodes. In several studies the prior use of stat...
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| Lenguaje: | Spanish / Castilian |
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Sociedad Chilena de Cardiología y Cirugía Cardiovascular
2012
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| Acceso en línea: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-85602012000200010 |
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oai:scielo:S0718-856020120002000102012-10-08Enfermedad cerebrovascular y estatinasPrat,Hernán Cerebrovascular accident statins treatment recommendations Summary: Cerebrovascular disease is one of the leading causes of death in Chile. Its main manifestation, CVA, is most frequent in elderly subjects. Approximately 70% of CVA recognize an ischemic origin, the rest corresponds to intracerebral bleeding episodes. In several studies the prior use of statins has been proven to reduce the incidence of CVA as well as improving their prognosis, in spite of a lack of significant correlation with statin's effects on serum cholesterol. Statin effects have been related to their pleiotropic properties, to reductions in Protein C levels and to activation of endothelial stem cells. American Stroke Association Guidelines (2011) recommend statins for CVA in subjects with high cardiovascular risk. Triglycerides have not been clearly shown to be a risk factor for CVA and no other lipid lowering agents are recommended in this settinginfo:eu-repo/semantics/openAccessSociedad Chilena de Cardiología y Cirugía CardiovascularRevista chilena de cardiología v.31 n.2 20122012-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-85602012000200010es10.4067/S0718-85602012000200010 |
| institution |
Scielo Chile |
| collection |
Scielo Chile |
| language |
Spanish / Castilian |
| topic |
Cerebrovascular accident statins treatment recommendations |
| spellingShingle |
Cerebrovascular accident statins treatment recommendations Prat,Hernán Enfermedad cerebrovascular y estatinas |
| description |
Summary: Cerebrovascular disease is one of the leading causes of death in Chile. Its main manifestation, CVA, is most frequent in elderly subjects. Approximately 70% of CVA recognize an ischemic origin, the rest corresponds to intracerebral bleeding episodes. In several studies the prior use of statins has been proven to reduce the incidence of CVA as well as improving their prognosis, in spite of a lack of significant correlation with statin's effects on serum cholesterol. Statin effects have been related to their pleiotropic properties, to reductions in Protein C levels and to activation of endothelial stem cells. American Stroke Association Guidelines (2011) recommend statins for CVA in subjects with high cardiovascular risk. Triglycerides have not been clearly shown to be a risk factor for CVA and no other lipid lowering agents are recommended in this setting |
| author |
Prat,Hernán |
| author_facet |
Prat,Hernán |
| author_sort |
Prat,Hernán |
| title |
Enfermedad cerebrovascular y estatinas |
| title_short |
Enfermedad cerebrovascular y estatinas |
| title_full |
Enfermedad cerebrovascular y estatinas |
| title_fullStr |
Enfermedad cerebrovascular y estatinas |
| title_full_unstemmed |
Enfermedad cerebrovascular y estatinas |
| title_sort |
enfermedad cerebrovascular y estatinas |
| publisher |
Sociedad Chilena de Cardiología y Cirugía Cardiovascular |
| publishDate |
2012 |
| url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-85602012000200010 |
| work_keys_str_mv |
AT prathernan enfermedadcerebrovascularyestatinas |
| _version_ |
1714206151042662400 |