Enfermedad cerebrovascular y estatinas

Enfermedad cerebrovascular y estatinas

Summary: Cerebrovascular disease is one of the leading causes of death in Chile. Its main manifestation, CVA, is most frequent in elderly subjects. Approximately 70% of CVA recognize an ischemic origin, the rest corresponds to intracerebral bleeding episodes. In several studies the prior use of stat...

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Main Author: Prat,Hernán
Language:Spanish / Castilian
Published: Sociedad Chilena de Cardiología y Cirugía Cardiovascular 2012
Subjects:
Cerebrovascular accident
statins
treatment recommendations
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-85602012000200010
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spelling oai:scielo:S0718-856020120002000102012-10-08Enfermedad cerebrovascular y estatinasPrat,Hernán Cerebrovascular accident statins treatment recommendations Summary: Cerebrovascular disease is one of the leading causes of death in Chile. Its main manifestation, CVA, is most frequent in elderly subjects. Approximately 70% of CVA recognize an ischemic origin, the rest corresponds to intracerebral bleeding episodes. In several studies the prior use of statins has been proven to reduce the incidence of CVA as well as improving their prognosis, in spite of a lack of significant correlation with statin's effects on serum cholesterol. Statin effects have been related to their pleiotropic properties, to reductions in Protein C levels and to activation of endothelial stem cells. American Stroke Association Guidelines (2011) recommend statins for CVA in subjects with high cardiovascular risk. Triglycerides have not been clearly shown to be a risk factor for CVA and no other lipid lowering agents are recommended in this settinginfo:eu-repo/semantics/openAccessSociedad Chilena de Cardiología y Cirugía CardiovascularRevista chilena de cardiología v.31 n.2 20122012-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-85602012000200010es10.4067/S0718-85602012000200010
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Cerebrovascular accident
statins
treatment recommendations
spellingShingle Cerebrovascular accident
statins
treatment recommendations
Prat,Hernán
Enfermedad cerebrovascular y estatinas
description Summary: Cerebrovascular disease is one of the leading causes of death in Chile. Its main manifestation, CVA, is most frequent in elderly subjects. Approximately 70% of CVA recognize an ischemic origin, the rest corresponds to intracerebral bleeding episodes. In several studies the prior use of statins has been proven to reduce the incidence of CVA as well as improving their prognosis, in spite of a lack of significant correlation with statin's effects on serum cholesterol. Statin effects have been related to their pleiotropic properties, to reductions in Protein C levels and to activation of endothelial stem cells. American Stroke Association Guidelines (2011) recommend statins for CVA in subjects with high cardiovascular risk. Triglycerides have not been clearly shown to be a risk factor for CVA and no other lipid lowering agents are recommended in this setting
author Prat,Hernán
author_facet Prat,Hernán
author_sort Prat,Hernán
title Enfermedad cerebrovascular y estatinas
title_short Enfermedad cerebrovascular y estatinas
title_full Enfermedad cerebrovascular y estatinas
title_fullStr Enfermedad cerebrovascular y estatinas
title_full_unstemmed Enfermedad cerebrovascular y estatinas
title_sort enfermedad cerebrovascular y estatinas
publisher Sociedad Chilena de Cardiología y Cirugía Cardiovascular
publishDate 2012
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-85602012000200010
work_keys_str_mv AT prathernan enfermedadcerebrovascularyestatinas
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