The effects of Spirulina platensis ( Arthrospira platensis ) and Saccharomyces cerevisiae on the distribution and cytokine production of CD4+ and CD8+ T-lymphocytes in rabbits

ABSTRACT. Natural additives have become one of the most alternative immune enhancer nowadays. In particular, Spirulina platensis (Arthrospira platensis) (SP) and Saccharomyces cerevisiae (SC) have been used for improving the immune system and quality of life. The aim of this study was to regulate th...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Seyidoglu,Nilay, Galip,Nurten, Budak,Ferah, Uzabaci,Ender
Lenguaje:	English
Publicado:	Universidad Austral de Chile. Facultad de Ciencias Veterinarias 2017
Materias:	rabbits Saccharomyces cerevisiae Spirulina platensis Arthrospira platensis immunity
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0719-81322017000300185
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:scielo:S0719-81322017000300185
record_format	dspace
spelling	oai:scielo:S0719-813220170003001852017-11-29The effects of Spirulina platensis ( Arthrospira platensis ) and Saccharomyces cerevisiae on the distribution and cytokine production of CD4+ and CD8+ T-lymphocytes in rabbitsSeyidoglu,NilayGalip,NurtenBudak,FerahUzabaci,Ender rabbits Saccharomyces cerevisiae Spirulina platensis Arthrospira platensis immunity ABSTRACT. Natural additives have become one of the most alternative immune enhancer nowadays. In particular, Spirulina platensis (Arthrospira platensis) (SP) and Saccharomyces cerevisiae (SC) have been used for improving the immune system and quality of life. The aim of this study was to regulate the immune effect of S. cerevisiae and S. platensis (A. platensis) combination. Forty male New Zealand white rabbits, aged 5-6 weeks, were analysed in 4 groups: Control (basal diet); SC (added 3 g/kg diet), SP (added 5% of the diet); SC and SP (added 3 g/kg SC and 5% SP of the diet). The entire experiment lasted 90 days. Blood samples were obtained by ear venipuncture on the 90th day. The CD4+ and CD8+ T lymphocyte values were determined by flow cytometry and cytokines (IFN-γ and IL-4) were determined by ELISA. According to the results, there were no significant differences in the expression of cytokines, but serum CD4+/CD8+ increased in the animals fed SP and SC+SP supplemented diets (3 g/kg and 5% of the diet, respectively). It was concluded that S. platensis (A. platensis) may be used as an immune enhancer, although further studies are needed to clarify the effects of spirulina supplement on immunity.info:eu-repo/semantics/openAccessUniversidad Austral de Chile. Facultad de Ciencias VeterinariasAustral journal of veterinary sciences v.49 n.3 20172017-09-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0719-81322017000300185en10.4067/S0719-81322017000300185
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	rabbits Saccharomyces cerevisiae Spirulina platensis Arthrospira platensis immunity
spellingShingle	rabbits Saccharomyces cerevisiae Spirulina platensis Arthrospira platensis immunity Seyidoglu,Nilay Galip,Nurten Budak,Ferah Uzabaci,Ender The effects of Spirulina platensis ( Arthrospira platensis ) and Saccharomyces cerevisiae on the distribution and cytokine production of CD4+ and CD8+ T-lymphocytes in rabbits
description	ABSTRACT. Natural additives have become one of the most alternative immune enhancer nowadays. In particular, Spirulina platensis (Arthrospira platensis) (SP) and Saccharomyces cerevisiae (SC) have been used for improving the immune system and quality of life. The aim of this study was to regulate the immune effect of S. cerevisiae and S. platensis (A. platensis) combination. Forty male New Zealand white rabbits, aged 5-6 weeks, were analysed in 4 groups: Control (basal diet); SC (added 3 g/kg diet), SP (added 5% of the diet); SC and SP (added 3 g/kg SC and 5% SP of the diet). The entire experiment lasted 90 days. Blood samples were obtained by ear venipuncture on the 90th day. The CD4+ and CD8+ T lymphocyte values were determined by flow cytometry and cytokines (IFN-γ and IL-4) were determined by ELISA. According to the results, there were no significant differences in the expression of cytokines, but serum CD4+/CD8+ increased in the animals fed SP and SC+SP supplemented diets (3 g/kg and 5% of the diet, respectively). It was concluded that S. platensis (A. platensis) may be used as an immune enhancer, although further studies are needed to clarify the effects of spirulina supplement on immunity.
author	Seyidoglu,Nilay Galip,Nurten Budak,Ferah Uzabaci,Ender
author_facet	Seyidoglu,Nilay Galip,Nurten Budak,Ferah Uzabaci,Ender
author_sort	Seyidoglu,Nilay
title	The effects of Spirulina platensis ( Arthrospira platensis ) and Saccharomyces cerevisiae on the distribution and cytokine production of CD4+ and CD8+ T-lymphocytes in rabbits
title_short	The effects of Spirulina platensis ( Arthrospira platensis ) and Saccharomyces cerevisiae on the distribution and cytokine production of CD4+ and CD8+ T-lymphocytes in rabbits
title_full	The effects of Spirulina platensis ( Arthrospira platensis ) and Saccharomyces cerevisiae on the distribution and cytokine production of CD4+ and CD8+ T-lymphocytes in rabbits
title_fullStr	The effects of Spirulina platensis ( Arthrospira platensis ) and Saccharomyces cerevisiae on the distribution and cytokine production of CD4+ and CD8+ T-lymphocytes in rabbits
title_full_unstemmed	The effects of Spirulina platensis ( Arthrospira platensis ) and Saccharomyces cerevisiae on the distribution and cytokine production of CD4+ and CD8+ T-lymphocytes in rabbits
title_sort	effects of spirulina platensis ( arthrospira platensis ) and saccharomyces cerevisiae on the distribution and cytokine production of cd4+ and cd8+ t-lymphocytes in rabbits
publisher	Universidad Austral de Chile. Facultad de Ciencias Veterinarias
publishDate	2017
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0719-81322017000300185
work_keys_str_mv	AT seyidoglunilay theeffectsofspirulinaplatensisarthrospiraplatensisandsaccharomycescerevisiaeonthedistributionandcytokineproductionofcd4andcd8tlymphocytesinrabbits AT galipnurten theeffectsofspirulinaplatensisarthrospiraplatensisandsaccharomycescerevisiaeonthedistributionandcytokineproductionofcd4andcd8tlymphocytesinrabbits AT budakferah theeffectsofspirulinaplatensisarthrospiraplatensisandsaccharomycescerevisiaeonthedistributionandcytokineproductionofcd4andcd8tlymphocytesinrabbits AT uzabaciender theeffectsofspirulinaplatensisarthrospiraplatensisandsaccharomycescerevisiaeonthedistributionandcytokineproductionofcd4andcd8tlymphocytesinrabbits AT seyidoglunilay effectsofspirulinaplatensisarthrospiraplatensisandsaccharomycescerevisiaeonthedistributionandcytokineproductionofcd4andcd8tlymphocytesinrabbits AT galipnurten effectsofspirulinaplatensisarthrospiraplatensisandsaccharomycescerevisiaeonthedistributionandcytokineproductionofcd4andcd8tlymphocytesinrabbits AT budakferah effectsofspirulinaplatensisarthrospiraplatensisandsaccharomycescerevisiaeonthedistributionandcytokineproductionofcd4andcd8tlymphocytesinrabbits AT uzabaciender effectsofspirulinaplatensisarthrospiraplatensisandsaccharomycescerevisiaeonthedistributionandcytokineproductionofcd4andcd8tlymphocytesinrabbits
_version_	1714207271024590848

The effects of Spirulina platensis ( Arthrospira platensis ) and Saccharomyces cerevisiae on the distribution and cytokine production of CD4+ and CD8+ T-lymphocytes in rabbits

Ejemplares similares