Drug resistance in parasitic helminths of veterinary importance in Chile: Status review and research needs

Abstract: The increasing development of anthelmintic resistance (AR) in parasites of livestock is threatening animal health and production worldwide. In Chile, studies evaluating the field efficacy of anthelmintics and the detection of AR have been performed since the 2000s, but until now, no previo...

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Autor principal:	Peña-Espinoza,Miguel
Lenguaje:	English
Publicado:	Universidad Austral de Chile. Facultad de Ciencias Veterinarias 2018
Materias:	anthelmintic resistance nematodes livestock Chile
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0719-81322018000200065
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spelling	oai:scielo:S0719-813220180002000652018-05-23Drug resistance in parasitic helminths of veterinary importance in Chile: Status review and research needsPeña-Espinoza,Miguel anthelmintic resistance nematodes livestock Chile Abstract: The increasing development of anthelmintic resistance (AR) in parasites of livestock is threatening animal health and production worldwide. In Chile, studies evaluating the field efficacy of anthelmintics and the detection of AR have been performed since the 2000s, but until now, no previous attempt has tried to systematise the available information. This article reviews general concepts about AR in helminths of veterinary importance, methods for diagnosis of AR and summarises the published reports of AR in Chile. Anthelmintic resistance in Chile has been reported in gastrointestinal nematodes of horses (benzimidazole resistance) and ruminants (sheep and cattle, macrocyclic lactone and benzimidazole resistance). However, these cases involved a limited number of selected farms and no further conclusions can be made of the status of parasite drug resistance at a regional or national level. No published cases of AR in Fasciola hepatica have been reported in Chilean livestock, but human infections with triclabendazole-resistant F. hepatica have been described in patients with previous consumption of watercress or untreated water from marshes grazed by livestock. Given the zoonotic potential and endemic nature of F. hepatica in Chile, it is urgent to determine the extent of liver fluke resistance. Current research gaps of the situation of AR in Chile and suggestions for the performance of laboratory and field studies are further discussed.info:eu-repo/semantics/openAccessUniversidad Austral de Chile. Facultad de Ciencias VeterinariasAustral journal of veterinary sciences v.50 n.2 20182018-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0719-81322018000200065en10.4067/S0719-81322018000200065
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	anthelmintic resistance nematodes livestock Chile
spellingShingle	anthelmintic resistance nematodes livestock Chile Peña-Espinoza,Miguel Drug resistance in parasitic helminths of veterinary importance in Chile: Status review and research needs
description	Abstract: The increasing development of anthelmintic resistance (AR) in parasites of livestock is threatening animal health and production worldwide. In Chile, studies evaluating the field efficacy of anthelmintics and the detection of AR have been performed since the 2000s, but until now, no previous attempt has tried to systematise the available information. This article reviews general concepts about AR in helminths of veterinary importance, methods for diagnosis of AR and summarises the published reports of AR in Chile. Anthelmintic resistance in Chile has been reported in gastrointestinal nematodes of horses (benzimidazole resistance) and ruminants (sheep and cattle, macrocyclic lactone and benzimidazole resistance). However, these cases involved a limited number of selected farms and no further conclusions can be made of the status of parasite drug resistance at a regional or national level. No published cases of AR in Fasciola hepatica have been reported in Chilean livestock, but human infections with triclabendazole-resistant F. hepatica have been described in patients with previous consumption of watercress or untreated water from marshes grazed by livestock. Given the zoonotic potential and endemic nature of F. hepatica in Chile, it is urgent to determine the extent of liver fluke resistance. Current research gaps of the situation of AR in Chile and suggestions for the performance of laboratory and field studies are further discussed.
author	Peña-Espinoza,Miguel
author_facet	Peña-Espinoza,Miguel
author_sort	Peña-Espinoza,Miguel
title	Drug resistance in parasitic helminths of veterinary importance in Chile: Status review and research needs
title_short	Drug resistance in parasitic helminths of veterinary importance in Chile: Status review and research needs
title_full	Drug resistance in parasitic helminths of veterinary importance in Chile: Status review and research needs
title_fullStr	Drug resistance in parasitic helminths of veterinary importance in Chile: Status review and research needs
title_full_unstemmed	Drug resistance in parasitic helminths of veterinary importance in Chile: Status review and research needs
title_sort	drug resistance in parasitic helminths of veterinary importance in chile: status review and research needs
publisher	Universidad Austral de Chile. Facultad de Ciencias Veterinarias
publishDate	2018
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0719-81322018000200065
work_keys_str_mv	AT penaespinozamiguel drugresistanceinparasitichelminthsofveterinaryimportanceinchilestatusreviewandresearchneeds
_version_	1714207274158784512

Drug resistance in parasitic helminths of veterinary importance in Chile: Status review and research needs

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