Effect of Mycobacterium bovis infection in cattle on changes in appetite-related hormones

Abstract: There are limited studies available for appetite-related hormonal changes in bovine tuberculosis, therefore the purpose of this study was to determine the changes in appetite-related hormones (leptin, ghrelin, and nesfatin -1) of cattle with tuberculosis and to clarify their possible roles...

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Autores principales: Askar,Sinasi, Askar,Tünay Kontas, Güzel,Murat
Lenguaje:English
Publicado: Universidad Austral de Chile. Facultad de Ciencias Veterinarias 2018
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0719-81322018000300119
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spelling oai:scielo:S0719-813220180003001192018-11-05Effect of Mycobacterium bovis infection in cattle on changes in appetite-related hormonesAskar,SinasiAskar,Tünay KontasGüzel,Murat bovine tuberculosis ghrelin leptin nesfatin-1 Abstract: There are limited studies available for appetite-related hormonal changes in bovine tuberculosis, therefore the purpose of this study was to determine the changes in appetite-related hormones (leptin, ghrelin, and nesfatin -1) of cattle with tuberculosis and to clarify their possible roles. A total of 30 cattle, comprising 15 clinically healthy cattle and 15 cattle infected with tuberculosis were enrolled in the study. The diagnosis of tuberculosis was performed by tuberculin skin test, and changes in the concentrations of ghrelin, leptin, nesfatin-1, lipid profile and muscular enzymes in cattle with tuberculosis were determined. It was found that nesfatin-1, ghrelin and muscular enzymes concentrations were higher in bovine infected with tuberculosis than in the healthy controls. On the other hand, leptin, triglyceride, low density lipoprotein (LDL), high density lipoprotein (HDL), and total cholesterol levels were all lower in the tuberculosis group when compared to the control group. In this study, we detected serum nesfatin-1 concentrations for the first time in Mycobacterium bovis infection in addition to the other known appetite-related hormones. The data suggest that increased concentrations of nesfatin-1 may play a role in weight loss in bovine tuberculosis, but there is a need for further studies to determine its exact role in the etiopathogenesis of bovine tuberculosis.info:eu-repo/semantics/openAccessUniversidad Austral de Chile. Facultad de Ciencias VeterinariasAustral journal of veterinary sciences v.50 n.3 20182018-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0719-81322018000300119en10.4067/S0719-81322018000300119
institution Scielo Chile
collection Scielo Chile
language English
topic bovine tuberculosis
ghrelin
leptin
nesfatin-1
spellingShingle bovine tuberculosis
ghrelin
leptin
nesfatin-1
Askar,Sinasi
Askar,Tünay Kontas
Güzel,Murat
Effect of Mycobacterium bovis infection in cattle on changes in appetite-related hormones
description Abstract: There are limited studies available for appetite-related hormonal changes in bovine tuberculosis, therefore the purpose of this study was to determine the changes in appetite-related hormones (leptin, ghrelin, and nesfatin -1) of cattle with tuberculosis and to clarify their possible roles. A total of 30 cattle, comprising 15 clinically healthy cattle and 15 cattle infected with tuberculosis were enrolled in the study. The diagnosis of tuberculosis was performed by tuberculin skin test, and changes in the concentrations of ghrelin, leptin, nesfatin-1, lipid profile and muscular enzymes in cattle with tuberculosis were determined. It was found that nesfatin-1, ghrelin and muscular enzymes concentrations were higher in bovine infected with tuberculosis than in the healthy controls. On the other hand, leptin, triglyceride, low density lipoprotein (LDL), high density lipoprotein (HDL), and total cholesterol levels were all lower in the tuberculosis group when compared to the control group. In this study, we detected serum nesfatin-1 concentrations for the first time in Mycobacterium bovis infection in addition to the other known appetite-related hormones. The data suggest that increased concentrations of nesfatin-1 may play a role in weight loss in bovine tuberculosis, but there is a need for further studies to determine its exact role in the etiopathogenesis of bovine tuberculosis.
author Askar,Sinasi
Askar,Tünay Kontas
Güzel,Murat
author_facet Askar,Sinasi
Askar,Tünay Kontas
Güzel,Murat
author_sort Askar,Sinasi
title Effect of Mycobacterium bovis infection in cattle on changes in appetite-related hormones
title_short Effect of Mycobacterium bovis infection in cattle on changes in appetite-related hormones
title_full Effect of Mycobacterium bovis infection in cattle on changes in appetite-related hormones
title_fullStr Effect of Mycobacterium bovis infection in cattle on changes in appetite-related hormones
title_full_unstemmed Effect of Mycobacterium bovis infection in cattle on changes in appetite-related hormones
title_sort effect of mycobacterium bovis infection in cattle on changes in appetite-related hormones
publisher Universidad Austral de Chile. Facultad de Ciencias Veterinarias
publishDate 2018
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0719-81322018000300119
work_keys_str_mv AT askarsinasi effectofmycobacteriumbovisinfectionincattleonchangesinappetiterelatedhormones
AT askartunaykontas effectofmycobacteriumbovisinfectionincattleonchangesinappetiterelatedhormones
AT guzelmurat effectofmycobacteriumbovisinfectionincattleonchangesinappetiterelatedhormones
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