Cardiac troponin I, fructosamine, and cardiovascular parameters in dogs with diabetes mellitus

Abstract: Diabetes mellitus (DM) is a common endocrinopathy in dogs, however, the relationship between canine DM and cardiomyopathy is still unclear. The aims of this study were: to evaluate serum troponin I concentrations in diabetic dogs under treatment with insulin; to evaluate the hypothesis tha...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Soares,Frederico A.C., Machado,Letícia, Carvalho,Guilherme L., González,Félix H.D., Poppl,Álan G.
Lenguaje:	English
Publicado:	Universidad Austral de Chile. Facultad de Ciencias Veterinarias 2018
Materias:	blood pressure cardiac biomarkers echocardiography endocrinology
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0719-81322018000300129
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:scielo:S0719-81322018000300129
record_format	dspace
spelling	oai:scielo:S0719-813220180003001292018-11-05Cardiac troponin I, fructosamine, and cardiovascular parameters in dogs with diabetes mellitusSoares,Frederico A.C.Machado,LetíciaCarvalho,Guilherme L.González,Félix H.D.Poppl,Álan G. blood pressure cardiac biomarkers echocardiography endocrinology Abstract: Diabetes mellitus (DM) is a common endocrinopathy in dogs, however, the relationship between canine DM and cardiomyopathy is still unclear. The aims of this study were: to evaluate serum troponin I concentrations in diabetic dogs under treatment with insulin; to evaluate the hypothesis that the time of DM diagnosis could influence the troponin I concentration; and to evaluate the relationship between biochemical and cardiovascular parameters in diabetic dogs. This is a cross-sectional study including diabetic canine patients under NPH insulin treatment. Troponin I concentration, systolic blood pressure (SBP), complete blood count, serum fructosamine concentration, biochemical profile, and Doppler echocardiography assesments were carried out in each patient, as well as in age- and size- matched healthy controls. All diabetic dogs had concentrations of troponin I below the limits of detection of the assay. There was no difference between cardiovascular parameters between diabetic and healthy control dogs. There was no correlation between time of DM diagnosis and cardiovascular parameters. There was a significant positive correlation between SBP and fructosamine in diabetic dogs (r=0.54; P<0.01). Diabetic dogs receiving insulin treatment, regardless of the time of diagnosis, do not have significantly elevated serum troponin I. The results also suggest that fructosamine levels can be associated with high blood pressure, suggesting a possible correlation between fructosamine levels and vascular complications.info:eu-repo/semantics/openAccessUniversidad Austral de Chile. Facultad de Ciencias VeterinariasAustral journal of veterinary sciences v.50 n.3 20182018-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0719-81322018000300129en10.4067/S0719-81322018000300129
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	blood pressure cardiac biomarkers echocardiography endocrinology
spellingShingle	blood pressure cardiac biomarkers echocardiography endocrinology Soares,Frederico A.C. Machado,Letícia Carvalho,Guilherme L. González,Félix H.D. Poppl,Álan G. Cardiac troponin I, fructosamine, and cardiovascular parameters in dogs with diabetes mellitus
description	Abstract: Diabetes mellitus (DM) is a common endocrinopathy in dogs, however, the relationship between canine DM and cardiomyopathy is still unclear. The aims of this study were: to evaluate serum troponin I concentrations in diabetic dogs under treatment with insulin; to evaluate the hypothesis that the time of DM diagnosis could influence the troponin I concentration; and to evaluate the relationship between biochemical and cardiovascular parameters in diabetic dogs. This is a cross-sectional study including diabetic canine patients under NPH insulin treatment. Troponin I concentration, systolic blood pressure (SBP), complete blood count, serum fructosamine concentration, biochemical profile, and Doppler echocardiography assesments were carried out in each patient, as well as in age- and size- matched healthy controls. All diabetic dogs had concentrations of troponin I below the limits of detection of the assay. There was no difference between cardiovascular parameters between diabetic and healthy control dogs. There was no correlation between time of DM diagnosis and cardiovascular parameters. There was a significant positive correlation between SBP and fructosamine in diabetic dogs (r=0.54; P<0.01). Diabetic dogs receiving insulin treatment, regardless of the time of diagnosis, do not have significantly elevated serum troponin I. The results also suggest that fructosamine levels can be associated with high blood pressure, suggesting a possible correlation between fructosamine levels and vascular complications.
author	Soares,Frederico A.C. Machado,Letícia Carvalho,Guilherme L. González,Félix H.D. Poppl,Álan G.
author_facet	Soares,Frederico A.C. Machado,Letícia Carvalho,Guilherme L. González,Félix H.D. Poppl,Álan G.
author_sort	Soares,Frederico A.C.
title	Cardiac troponin I, fructosamine, and cardiovascular parameters in dogs with diabetes mellitus
title_short	Cardiac troponin I, fructosamine, and cardiovascular parameters in dogs with diabetes mellitus
title_full	Cardiac troponin I, fructosamine, and cardiovascular parameters in dogs with diabetes mellitus
title_fullStr	Cardiac troponin I, fructosamine, and cardiovascular parameters in dogs with diabetes mellitus
title_full_unstemmed	Cardiac troponin I, fructosamine, and cardiovascular parameters in dogs with diabetes mellitus
title_sort	cardiac troponin i, fructosamine, and cardiovascular parameters in dogs with diabetes mellitus
publisher	Universidad Austral de Chile. Facultad de Ciencias Veterinarias
publishDate	2018
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0719-81322018000300129
work_keys_str_mv	AT soaresfredericoac cardiactroponinifructosamineandcardiovascularparametersindogswithdiabetesmellitus AT machadoleticia cardiactroponinifructosamineandcardiovascularparametersindogswithdiabetesmellitus AT carvalhoguilhermel cardiactroponinifructosamineandcardiovascularparametersindogswithdiabetesmellitus AT gonzalezfelixhd cardiactroponinifructosamineandcardiovascularparametersindogswithdiabetesmellitus AT popplalang cardiactroponinifructosamineandcardiovascularparametersindogswithdiabetesmellitus
_version_	1714207276156321792

Cardiac troponin I, fructosamine, and cardiovascular parameters in dogs with diabetes mellitus

Ejemplares similares