Electrochemotherapy in the treatment of neoplasms in dogs and cats

Abstract: Electrochemotherapy (ECT) is a technique that combines chemotherapy with local application of specific electric pulses with the aim of increasing the permeability of the plasma membrane in a reversible way, improving the influx of chemotherapeutic drugs into the cytoplasm and potentiating...

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Autores principales:	Rangel,Marcelo M.M., Luz,Jean C.S., Oliveira,Krishna D., Ojeda,Javier, Freytag,Jennifer O., Suzuki,Daniela O.
Lenguaje:	English
Publicado:	Universidad Austral de Chile. Facultad de Ciencias Veterinarias 2019
Materias:	bleomycin electroporation veterinary oncology electrochemotherapy
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0719-81322019000200045
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spelling	oai:scielo:S0719-813220190002000452019-05-17Electrochemotherapy in the treatment of neoplasms in dogs and catsRangel,Marcelo M.M.Luz,Jean C.S.Oliveira,Krishna D.Ojeda,JavierFreytag,Jennifer O.Suzuki,Daniela O. bleomycin electroporation veterinary oncology electrochemotherapy Abstract: Electrochemotherapy (ECT) is a technique that combines chemotherapy with local application of specific electric pulses with the aim of increasing the permeability of the plasma membrane in a reversible way, improving the influx of chemotherapeutic drugs into the cytoplasm and potentiating their cytotoxic effects. This technique has broadened the range of possible treatments for oncological patients, either on its own or as adjuvant to surgical procedures. It is especially useful in tumors located in regions with only a small surgical safety margin, such as the limb extremities, skull, oral cavity, neck and perianal region, among others. ECT makes it feasible to perform procedures more conservatively, or even to perform otherwise infeasible procedures, by expanding the margins without removing healthy tissues. The objective of this paper is to provide a brief bibliographic review of the principles, applications and future possibilities of electrochemotherapy, helping to disseminate pertinent information about this relatively new technique for the treatment of cancer.info:eu-repo/semantics/openAccessUniversidad Austral de Chile. Facultad de Ciencias VeterinariasAustral journal of veterinary sciences v.51 n.2 20192019-05-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0719-81322019000200045en10.4067/S0719-81322019000200045
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	bleomycin electroporation veterinary oncology electrochemotherapy
spellingShingle	bleomycin electroporation veterinary oncology electrochemotherapy Rangel,Marcelo M.M. Luz,Jean C.S. Oliveira,Krishna D. Ojeda,Javier Freytag,Jennifer O. Suzuki,Daniela O. Electrochemotherapy in the treatment of neoplasms in dogs and cats
description	Abstract: Electrochemotherapy (ECT) is a technique that combines chemotherapy with local application of specific electric pulses with the aim of increasing the permeability of the plasma membrane in a reversible way, improving the influx of chemotherapeutic drugs into the cytoplasm and potentiating their cytotoxic effects. This technique has broadened the range of possible treatments for oncological patients, either on its own or as adjuvant to surgical procedures. It is especially useful in tumors located in regions with only a small surgical safety margin, such as the limb extremities, skull, oral cavity, neck and perianal region, among others. ECT makes it feasible to perform procedures more conservatively, or even to perform otherwise infeasible procedures, by expanding the margins without removing healthy tissues. The objective of this paper is to provide a brief bibliographic review of the principles, applications and future possibilities of electrochemotherapy, helping to disseminate pertinent information about this relatively new technique for the treatment of cancer.
author	Rangel,Marcelo M.M. Luz,Jean C.S. Oliveira,Krishna D. Ojeda,Javier Freytag,Jennifer O. Suzuki,Daniela O.
author_facet	Rangel,Marcelo M.M. Luz,Jean C.S. Oliveira,Krishna D. Ojeda,Javier Freytag,Jennifer O. Suzuki,Daniela O.
author_sort	Rangel,Marcelo M.M.
title	Electrochemotherapy in the treatment of neoplasms in dogs and cats
title_short	Electrochemotherapy in the treatment of neoplasms in dogs and cats
title_full	Electrochemotherapy in the treatment of neoplasms in dogs and cats
title_fullStr	Electrochemotherapy in the treatment of neoplasms in dogs and cats
title_full_unstemmed	Electrochemotherapy in the treatment of neoplasms in dogs and cats
title_sort	electrochemotherapy in the treatment of neoplasms in dogs and cats
publisher	Universidad Austral de Chile. Facultad de Ciencias Veterinarias
publishDate	2019
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0719-81322019000200045
work_keys_str_mv	AT rangelmarcelomm electrochemotherapyinthetreatmentofneoplasmsindogsandcats AT luzjeancs electrochemotherapyinthetreatmentofneoplasmsindogsandcats AT oliveirakrishnad electrochemotherapyinthetreatmentofneoplasmsindogsandcats AT ojedajavier electrochemotherapyinthetreatmentofneoplasmsindogsandcats AT freytagjennifero electrochemotherapyinthetreatmentofneoplasmsindogsandcats AT suzukidanielao electrochemotherapyinthetreatmentofneoplasmsindogsandcats
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Electrochemotherapy in the treatment of neoplasms in dogs and cats

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