PROPOSALS FOR EMBRYONIC STEM CELL PRODUCTION WITHOUT DESTROYING HUMAN EMBRYOS: SCIENTIFIC AND BIOETHICAL CHALLENGES

The possibility of using human embryonic stem cells (ESC) for therapeutic purposes raises serious ethical objections, the most fundamental one being that until recently the only way to obtain ESC was with procedures that necessarily destroyed living human embryos. Due to this, research in this field...

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Autores principales:	Ventura-Juncá,Patricio, Santos,Manuel, Larraín,Juan
Lenguaje:	English
Publicado:	Centro Interdisciplinario de Estudios en Bioética, Universidad de Chile 2009
Materias:	ethics embryonic stem cells adult stem cells
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S1726-569X2009000200014
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spelling	oai:scielo:S1726-569X20090002000142010-09-07PROPOSALS FOR EMBRYONIC STEM CELL PRODUCTION WITHOUT DESTROYING HUMAN EMBRYOS: SCIENTIFIC AND BIOETHICAL CHALLENGESVentura-Juncá,PatricioSantos,ManuelLarraín,Juan ethics embryonic stem cells adult stem cells The possibility of using human embryonic stem cells (ESC) for therapeutic purposes raises serious ethical objections, the most fundamental one being that until recently the only way to obtain ESC was with procedures that necessarily destroyed living human embryos. Due to this, research in this field has been rejected by many scientists, bioeticists, and has been banned by law in several countries. Efforts have been made to find procedures to obtain ESC without destroying embyros or putting them at risk. This paper reviews the scientific, technical and ethical aspects of the different strategies developed for this purpose. Embryo biopsy, ESC obtained from "dead" embryos, ESC produced by "parthenogenetic embryos", ESC obtained by Altered Nuclear Transfer and induced pluripotent cells (iPSC) obtained by direct epigenetic reprogramming of somatic cells are the main five alternative reported in recent studies.info:eu-repo/semantics/openAccessCentro Interdisciplinario de Estudios en Bioética, Universidad de ChileActa bioethica v.15 n.2 20092009-11-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S1726-569X2009000200014en10.4067/S1726-569X2009000200014
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	ethics embryonic stem cells adult stem cells
spellingShingle	ethics embryonic stem cells adult stem cells Ventura-Juncá,Patricio Santos,Manuel Larraín,Juan PROPOSALS FOR EMBRYONIC STEM CELL PRODUCTION WITHOUT DESTROYING HUMAN EMBRYOS: SCIENTIFIC AND BIOETHICAL CHALLENGES
description	The possibility of using human embryonic stem cells (ESC) for therapeutic purposes raises serious ethical objections, the most fundamental one being that until recently the only way to obtain ESC was with procedures that necessarily destroyed living human embryos. Due to this, research in this field has been rejected by many scientists, bioeticists, and has been banned by law in several countries. Efforts have been made to find procedures to obtain ESC without destroying embyros or putting them at risk. This paper reviews the scientific, technical and ethical aspects of the different strategies developed for this purpose. Embryo biopsy, ESC obtained from "dead" embryos, ESC produced by "parthenogenetic embryos", ESC obtained by Altered Nuclear Transfer and induced pluripotent cells (iPSC) obtained by direct epigenetic reprogramming of somatic cells are the main five alternative reported in recent studies.
author	Ventura-Juncá,Patricio Santos,Manuel Larraín,Juan
author_facet	Ventura-Juncá,Patricio Santos,Manuel Larraín,Juan
author_sort	Ventura-Juncá,Patricio
title	PROPOSALS FOR EMBRYONIC STEM CELL PRODUCTION WITHOUT DESTROYING HUMAN EMBRYOS: SCIENTIFIC AND BIOETHICAL CHALLENGES
title_short	PROPOSALS FOR EMBRYONIC STEM CELL PRODUCTION WITHOUT DESTROYING HUMAN EMBRYOS: SCIENTIFIC AND BIOETHICAL CHALLENGES
title_full	PROPOSALS FOR EMBRYONIC STEM CELL PRODUCTION WITHOUT DESTROYING HUMAN EMBRYOS: SCIENTIFIC AND BIOETHICAL CHALLENGES
title_fullStr	PROPOSALS FOR EMBRYONIC STEM CELL PRODUCTION WITHOUT DESTROYING HUMAN EMBRYOS: SCIENTIFIC AND BIOETHICAL CHALLENGES
title_full_unstemmed	PROPOSALS FOR EMBRYONIC STEM CELL PRODUCTION WITHOUT DESTROYING HUMAN EMBRYOS: SCIENTIFIC AND BIOETHICAL CHALLENGES
title_sort	proposals for embryonic stem cell production without destroying human embryos: scientific and bioethical challenges
publisher	Centro Interdisciplinario de Estudios en Bioética, Universidad de Chile
publishDate	2009
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S1726-569X2009000200014
work_keys_str_mv	AT venturajuncapatricio proposalsforembryonicstemcellproductionwithoutdestroyinghumanembryosscientificandbioethicalchallenges AT santosmanuel proposalsforembryonicstemcellproductionwithoutdestroyinghumanembryosscientificandbioethicalchallenges AT larrainjuan proposalsforembryonicstemcellproductionwithoutdestroyinghumanembryosscientificandbioethicalchallenges
_version_	1714207334400524288

PROPOSALS FOR EMBRYONIC STEM CELL PRODUCTION WITHOUT DESTROYING HUMAN EMBRYOS: SCIENTIFIC AND BIOETHICAL CHALLENGES

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