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  1. 1221
    Cerebral vascular amyloid seeds drive amyloid β-protein fibril assembly with a distinct anti-parallel structure
    “...Cerebrovascular accumulation of Aβ is a common feature of Alzheimer’s disease, though it is unclear...”
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  2. 1222
    Elevated glucose and oligomeric β-amyloid disrupt synapses via a common pathway of aberrant protein S-nitrosylation
    “...Alzheimer's disease is linked to metabolic syndrome and Type-2 diabetes, but the mechanism behind...”
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  3. 1223
    Beta-amyloid production in neurons is regulated by astrocyte-derived cholesterol
    por Karli Montague-Cardoso
    Publicado 2021
    “...The accumulation of amyloid β (Aβ) in the brain is an established feature of Alzheimer’s disease...”
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  4. 1224
    Inhibition of amyloid beta toxicity in zebrafish with a chaperone-gold nanoparticle dual strategy
    “...Treating Alzheimer’s disease, one of the most common neurodegenerative diseases, is of wide...”
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  5. 1225
    Different soluble aggregates of Aβ42 can give rise to cellular toxicity through different mechanisms
    “... to Alzheimer’s disease. This study shows how different types of Aβ42 aggregates are associated with distinct...”
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  6. 1226
    A blood miRNA signature associates with sporadic Creutzfeldt-Jakob disease diagnosis
    “... that are downregulated in sCJD patients, and discriminate sCJD from Alzheimer’s disease patients and healthy controls....”
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  7. 1227
    Subtyping of circulating exosome-bound amyloid β reflects brain plaque deposition
    “...Detecting Alzheimer’s disease from blood samples is challenging because amyloid β blood levels...”
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  8. 1228
    Increased amyloidogenic APP processing in APOE ɛ4-negative individuals with cerebral β-amyloidosis
    “...Autosomal dominant Alzheimer's disease is thought to be caused by increased amyloidogenic APP...”
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  9. 1229
    Molecular estimation of neurodegeneration pseudotime in older brains
    “...The limited understanding of the temporal molecular changes in late-onset Alzheimer’s disease...”
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  10. 1230
    Earliest accumulation of β-amyloid occurs within the default-mode network and concurrently affects brain connectivity
    “... in the brain of individuals with Alzheimer’s disease and here the authors use this temporal pattern to identify...”
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  11. 1231
    Untangling the brain’s neuroinflammatory and neurodegenerative transcriptional responses
    “... transcriptomes of neurons, astrocytes, and microglia from Alzheimer's disease model brains and identify hundreds...”
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  12. 1232
    Prediction and verification of the AD-FTLD common pathomechanism based on dynamic molecular network analysis
    “... models of Alzheimer’s disease, they observe conserved signaling networks and confirm a therapeutic effect...”
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  13. 1233
    Plasma N-terminal tau fragment levels predict future cognitive decline and neurodegeneration in healthy elderly individuals
    “... individuals with Alzheimer’s disease from healthy controls. Here the authors show that plasma levels of NT1...”
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  14. 1234
    Plasmonic nanoparticle amyloid corona for screening Aβ oligomeric aggregate-degrading drugs
    “...Effective screening of drugs to treat amyloid oligomeric aggregates associated with Alzheimer’s...”
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  15. 1235
    Mapping synaptic glutamate transporter dysfunction in vivo to regions surrounding Aβ plaques by iGluSnFR two-photon imaging
    “...In Alzheimer’s disease (AD), neural hyperactivity has been shown to occur in the regions...”
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  16. 1236
    UBE4B, a microRNA-9 target gene, promotes autophagy-mediated Tau degradation
    “...Hyperphosphorylated Tau accumulation promotes neurodegeneration in Alzheimer’s disease. Here...”
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  17. 1237
    Síntomas psicológicos y conductuales asociados a demencias: actualización terapéutica
    “..., there is not enough scientific evidence about their real effectiveness and security in patients with Alzheimer...”
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  18. 1238
    Identification of two novel mutations, PSEN1 E280K and PRNP G127S, in a Malaysian family
    “...: Alzheimer’s disease (AD) is the most common form of dementia, which can be categorized into two main...”
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  19. 1239
    Regulation of GABA(A) and glutamate receptor expression, synaptic facilitation and long-term potentiation in the hippocampus of prion mutant mice.
    “... point to PrP(c) as a target for putative therapies in Alzheimer's disease. However, our results indicate...”
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  20. 1240
    The Human Disease-Associated Aβ Amyloid Core Sequence Forms Functional Amyloids in a Fungal Adhesin
    “... Protein amyloid aggregates are markers of neurodegenerative diseases such as Alzheimer’s and Parkinsonism...”
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