Functional apoptosis profiling identifies MCL-1 and BCL-xL as prognostic markers and therapeutic targets in advanced thymomas and thymic carcinomas

by Denise Müller, Paolo Mazzeo, Raphael Koch, Mark-Sebastian Bösherz, Stefan Welter, Alexander von Hammerstein-Equord, Marc Hinterthaner, Lucia Cordes, Djeda Belharazem, Alexander Marx, Philipp Ströbel, Stefan Küffer
Published 2021

Venetoclax in Acute Myeloid Leukemia: Molecular Basis, Evidences for Preclinical and Clinical Efficacy and Strategies to Target Resistance

by Sylvain Garciaz, Colombe Saillard, Yosr Hicheri, Marie-Anne Hospital, Norbert Vey
Published 2021

Inhibition of the Anti-Apoptotic Bcl-2 Family by BH3 Mimetics Sensitize the Mitochondrial Permeability Transition Pore Through Bax and Bak

by Pooja Patel, Pooja Patel, Arielys Mendoza, Arielys Mendoza, Dexter J. Robichaux, Dexter J. Robichaux, Meng C. Wang, Meng C. Wang, Meng C. Wang, Xander H. T. Wehrens, Xander H. T. Wehrens, Jason Karch, Jason Karch
Published 2021

BH3-mimetics: recent developments in cancer therapy

by Paul A. Townsend, Maria V. Kozhevnikova, Olivier N. F. Cexus, Andrey A. Zamyatnin, Surinder M. Soond
Published 2021