Effect of menstrual cycle phase, menstrual irregularities and hormonal contraceptive use on anterior knee laxity and non-contact anterior cruciate ligament injury occurrence in wom...

por Kirsty Jayne Elliott-Sale, Paul A Swinton, Eimear Dolan, Craig Sale, Sandra J Shultz, Elisa Nédélec, Elvis Foli, Jessica Piasecki, Joseph J Matthews
Publicado 2021

4-1BB and optimized CD28 co-stimulation enhances function of human mono-specific and bi-specific third-generation CAR T cells

por Frederick L Locke, Yannick Bulliard, Bin Yu, Marco L Davila, Emiliano Roselli, Justin C Boucher, Gongbo Li, Hiroshi Kotani, Kristen Spitler, Kayla Reid, Estelle V Cervantes, Nhan Tu, Sae Bom Lee
Publicado 2021

Integrating health services for HIV infection, diabetes and hypertension in sub-Saharan Africa: a cohort study

por Tinevimbo Shiri, Duolao Wang, Sarah Maongezi, Moffat J Nyirenda, Nelson Sewankambo, Levicatus Mugenyi, Josephine Birungi, Anupam Garrib, Sokoine Kivuyo, Ivan Namakoola, Joseph Okebe, Geoff Gill, Gerald Mutungi, Joshua Musinguzi, Janneth Mghamba, Kenneth Mugisha, Peter G Smith, Sayoki Godfrey Mfinanga, Louis Wihelmus Niessen, Bernard M Etukoit, Janet Lutale, Shimwela Meshack, Ayoub Kakande
Publicado 2021

Listen, look, link and learn: a stepwise approach to use narrative quality data within resident-family-nursing staff triads in nursing homes for quality improvements

por Jos M G A Schols, Jan P H Hamers, Katya Y J Sion, Johanna E R Rutten, Erica de Vries, Sandra M G Zwakhalen, Gaby Odekerken-Schröder, Hilde Verbeek
Publicado 2021

Diagnosis of infection after cardiovascular surgery (DICS): a study protocol for developing and validating a prediction model in prospective observational study

por HE Zhang, Zhong Chen, Ke Pan, Hai-Tao Zhang, Xi-Kun Han, Chuang-Shi Wang, Ze-Shi Li, Kai Zhong, Tuo Pan, Dong-Jin Wang
Publicado 2021

Mitochondrial reactive oxygen species trigger metformin-dependent antitumor immunity via activation of Nrf2/mTORC1/p62 axis in tumor-infiltrating CD8T lymphocytes

por Kazuhiro Kakimi, Hirokazu Matsushita, Masaaki Komatsu, Eiryo Kawakami, Mikako Nishida, Nahoko Yamashita, Taisaku Ogawa, Keita Koseki, Eiji Warabi, Tomoyuki Ohue, Katsuyuki Shiroguchi, Heiichiro Udono
Publicado 2021

Incidence of ‘new-onset’ constipation and associated factors during lockdown due to the COVID-19 pandemic

por Bryan Adrian Priego-Parra, Jose Maria Remes-Troche, Enrique Coss-Adame, Mercedes Amieva-Balmori, José Antonio Velarde-Ruiz Velasco, Paulo César Gómez-Castaños, Ricardo Flores-Rendón, Octavio Gómez-Escudero, María Celina Rodríguez-Leal, Cristina Durán-Rosas, Samanta Mayanin Pinto-Gálvez, Arturo Triana-Romero
Publicado 2021

HbA1c performs well in monitoring glucose control even in populations with high prevalence of medical conditions that may alter its reliability: the OPTIMAL observational multicent...

por Timothy J McDonald, Beverley M Shields, Andrew T Hattersley, Angus G Jones, Lauren R Rodgers, Rosamund Greiner, Anxious J Niwaha, Priscilla A Balungi, Raymond Mwebaze
Publicado 2021

DNA methylation-based signature of CD8+ tumor-infiltrating lymphocytes enables evaluation of immune response and prognosis in colorectal cancer

por Rish K Pai, Yu Zhang, Daniel D Buchanan, William M Grady, Aung Ko Win, Xiaolin Wang, Bang Hu, Polly A Newcomb, Meijin Huang, Qi Zou, Donglin Ren, Guannan Tang, Huichuan Yu, Yanxin Luo
Publicado 2021

Immunosuppression reduction when administering a booster dose of the BNT162b2 mRNA SARS-CoV-2 vaccine in kidney transplant recipients without adequate humoral response following tw...

por Dafna Yahav, Benaya Rozen-Zvi, Tiki Mashraki, Alaa Atamna, Haim Ben-Zvi, Erez Bar-Haim, R Rahamimov
Publicado 2021

Plasma protein N-glycosylation is associated with cardiovascular disease, nephropathy, and retinopathy in type 2 diabetes

por Femke Rutters, Amber A van der Heijden, Manfred Wuhrer, Mandy van Hoek, Eric J G Sijbrands, Aloysius G Lieverse, Viktoria Dotz, Emma Schoep, Elham Memarian, Roderick C Slieker, Leen M 't Hart, Giel Nijpels, Roosmarijn F L Lemmers
Publicado 2021

Helicobacter pylori infection disturbs the tumor immune microenvironment and is associated with a discrepant prognosis in gastric de novo diffuse large B-cell lymphoma

por Qingyuan Zhang, Jingshu Geng, Yuwei Deng, Wenjia Su, Junwen Zhu, Hongfei Ji, Xiaoping Zhou, Jiayu Zhu
Publicado 2021

Effect of specialised versus generalised outpatient treatment for bipolar disorder: the CAG Bipolar trial - study protocol for a randomised controlled trial

por Maria Faurholt-Jepsen, Ida Hageman, Maj Vinberg, Lars Vedel Kessing, Ellen Margrethe Christensen, Natacha Blauenfeldt Kyster, Pernille Bondo-Kozuch, Birgitte Vejstrup, Birte Smidt, Anne-Marie Bangsgaard Jørgensen, Raben Rosenberg, Darius Mardosas, Louise Behrend Rasmussen, Kim Brøndmark, Signe Seidelin, Ida Palmblad Sarauw-Nielsen, Annemette Larsen
Publicado 2021

Gastrointestinal recovery after surgery: protocol for a systematic review

por Suzanne Edwards, Michael Horowitz, Karen L Jones, Guy J Maddern, Joshua G Kovoor, Brandon Stretton, Jonathan Henry W Jacobsen, Aashray K Gupta, Christopher D Ovenden, Joseph N Hewitt, John M Glynatsis, Kaitryn Campbell, Gayatri P Asokan, David R Tivey, Wendy J Babidge, Christopher K Rayner, Adrian A Anthony, Markus I Trochsler, Peter J Hewett
Publicado 2021

Clinical effectiveness and components of Home-pulmonary rehabilitation for people with chronic respiratory diseases: a systematic review protocol

por Julia Patrick Engkasan, Ee Ming Khoo, Su May Liew, Nik Sherina Hanafi, Roberto A Rabinovich, Md Nazim Uzzaman, Soo Chin Chan, Ranita Hisham Shunmugam, Dhiraj Agarwal, G M Monsur Habib, Tracy Jackson, Paul Jebaraj, Fatim Tahirah Mirza
Publicado 2021

Impact of mRNA vaccines in curtailing SARS-CoV-2 infection and disability leave utilisation among healthcare workers during the COVID-19 pandemic: cross-sectional analysis from a t...

por Robert Phillips, Farhaan S Vahidy, Alan P Pan, Kobina Hagan, Abdulaziz T Bako, Henry Dirk Sostman, Roberta L Schwartz, Marc L Boom
Publicado 2021

Coronary CT angiography for improved assessment of patients with acute chest pain and low-range positive high-sensitivity troponins: study protocol for a prospective, observational...

por Ricardo PJ Budde, Jesse Habets, Admir Dedic, Peter Damman, Jeroen Schaap, Murat Arslan, Bart Van Gorsel, Sebastiaan CAM Bekkers, Yvonne JM Van Cauteren, Eric A Dubois
Publicado 2021

Phase II multicentre, double-blind, randomised trial of ustekinumab in adolescents with new-onset type 1 diabetes (USTEK1D): trial protocol

por Greg W Fegan, Hayley Anne Hutchings, Colin Dayan, Stephen Hiles, Stephen Luzio, Nadim Bashir, Gail Holland, Amy Brown, Wai Yee Cheung, Kymberley Carter, Jane Bowen-Morris, Gareth Dunseath, Timothy Tree, Jennie Hsiu Mien Yang, Ashish Marwaha, Mohammad Alhadj Ali, Rachel Stenson, Susie Marques-Jones, Danijela Tatovic
Publicado 2021

Vaccine nationalism and internationalism: perspectives of COVID-19 vaccine trial participants in the United Kingdom

por Tonia Thomas, Samantha Vanderslott, Andrew J Pollard, Arabella Stuart, John Henry, Katherine Emary, Rebecca te Water Naude, Marcus English, Maia Patrick-Smith, Naomi Douglas, Maria Moore, Susanne H Hodgson
Publicado 2021

Interleukin-30 feeds breast cancer stem cells via CXCL10 and IL23 autocrine loops and shapes immune contexture and host outcome

por Carlo Sorrentino, Paola Lanuti, Emma Di Carlo, Alice Turdo, Matilde Todaro, Stefania Livia Ciummo, Luigi D'Antonio, Cristiano Fieni
Publicado 2021