Effectiveness of a customised mobile phone text messaging intervention supported by data from activity monitors for improving lifestyle factors related to the risk of type 2 diabet...

por Aravinda Thiagalingam, Victoria Flood, N Wah Cheung, David Simmons, Simone Marschner, Dharmintra Pasupathy, Ben J Smith, Mark McClean, Suja Padmanabhan, Sarah Melov, Cellina Ching
Publicado 2021

Intratumoral combination therapy with poly(I:C) and resiquimod synergistically triggers tumor-associated macrophages for effective systemic antitumoral immunity

por Alberto Mantovani, Marco Erreni, Paola Allavena, Diego Serrano, Miriam Redrado, Francisco Exposito, Alfonso Calvo, Clément Anfray, Francesco Mainini, Elisabeth Digifico, Akihiro Maeda, Marina Sironi, Achille Anselmo, Aldo Ummarino, Sara Gandoy, Marvin Martens, Susana Bravo, Fernando Torres Andón
Publicado 2021

‘Learn from the lessons and don’t forget them’: identifying transferable lessons for COVID-19 from meningitis A, yellow fever and Ebola virus disease vaccination campaigns

por Julie Collins, Daniel G Bausch, Hana Rohan, Gloria Ikilezi, Hilary Bower, Rosie Westerveld, Kate A Nelson, Siobhan Lazenby, Rebecca Bartlein, David S Kennedy
Publicado 2021

Systematic preclinical evaluation of CD33-directed chimeric antigen receptor T cell immunotherapy for acute myeloid leukemia defines optimized construct design

por Haiying Qin, Nirali N Shah, Terry J Fry, Lila Yang, John A Chukinas, Samiksha Tarun, Marie Pouzolles, Christopher D Chien, Lisa M Niswander, Anthony R Welch, Sarah K Tasian, Naomi A Taylor
Publicado 2021

Quick-Wee versus bladder stimulation to collect midstream urine from precontinent infants under 1 year of age: a study protocol for a randomised controlled trial (ES.Stimquick.U)

por Anne-Laure Hérissé, Diane Demonchy, Hervé Haas, Antoine Tran, Jean Bréaud, Anne Rancurel, Sarah Marchal, Jade Janicot, Julie Salicis, Marco Olla, Etienne Bérard, Julie Bernardor, Chloé Ribet, Emma Freyssinet, Dominique Donzeau, Jonathan Desmontils, Clara Schori-Fortier, Eric Fontas
Publicado 2021

Combined CTLA-4 and PD-L1 blockade in patients with chemotherapy-naïve metastatic castration-resistant prostate cancer is associated with increased myeloid and neutrophil immune su...

por Hong Chen, Padmanee Sharma, James P Allison, Sumit K Subudhi, Sonali Jindal, Sreyashi Basu, Bilal A Siddiqui, Paul G Corn, Ana M Aparicio, Shalini S Yadav, Rebecca S S Tidwell, Ashwin Varma, Christopher J Logothetis
Publicado 2021

Avelumab for platinum-ineligible/refractory recurrent and/or metastatic squamous cell carcinoma of the head and neck: phase Ib results from the JAVELIN Solid Tumor trial

por Nicolas Penel, Ulrich Keilholz, Ani Balmanoukian, Manish R Patel, Sanjay Goel, Keun-Wook Lee, Alain Mita, Christophe Le Tourneau, Deborah J Wong, Patrick Schöffski, Marcis Bajars, Amaury Daste, Hans Juergen Grote, Dongli Zhou, Michael S Gordon, Martin Gutierrez, Damien Vansteene, Joël Guigay
Publicado 2021

Temocillin versus meropenem for the targeted treatment of bacteraemia due to third-generation cephalosporin-resistant Enterobacterales (ASTARTÉ): protocol for a randomised, pragmat...

por Clara M Rosso-Fernández, Pilar Retamar, Belén Gutiérrez-Gutiérrez, Alvaro Pascual, Elena Salamanca, Vicente Merino, Luis Eduardo López-Cortés, Alicia Marín-Candón, Natalia Bustos de Godoy, Lorena López-Cerero, Lydia Barrera Pulido, Irene Borreguero Borreguero, María José León, Manuel Camean-Fernández
Publicado 2021

Cost-effectiveness of direct discharge from the emergency department of patients with simple stable injuries in the Netherlands

por Johanna M van Dongen, J Carel Goslings, Robert Haverlag, Thijs H Geerdink, Ruben N van Veen, Niek J Geerdink, Bas A Uijterwijk, Ruth J Stoffels
Publicado 2021

Gastric venous reconstruction to reduce gastric venous congestion after total pancreatectomy: study protocol of a single-centre prospective non-randomised observational study (IDEA...

por Thilo Hackert, Markus W Büchler, Arianeb Mehrabi, Anja Schaible, Markus Mieth, Pascal Probst, Felix Nickel, Martin Loos, Ali Ramouz, Arash Dooghaie Moghadam
Publicado 2021

Facilitators and barriers to implementation of Alberta family integrated care (FICare) in level II neonatal intensive care units: a qualitative process evaluation substudy of a mul...

por Kelly Mrklas, Wanrudee Isaranuwatchai, Khalid Aziz, Vibhuti Shah, Jeffrey Hoch, Deborah A McNeil, Christopher Naugler, Henry T Stelfox, Abhay Lodha, Radha Chari, Amuchou Soraisham, Natalie V Scime, Pilar Zanoni, Karen Benzies, Karen M Benzies, Jeanne Scotland, Jill Larocque, Harish Amin, Sandra Walker-Kendall, Alberta Akierman, Ernest Phillipos
Publicado 2021

MET overexpression contributes to STAT4-PD-L1 signaling activation associated with tumor-associated, macrophages-mediated immunosuppression in primary glioblastomas

por Zheng Zhao, Tao Jiang, Shou-Wei Li, Yong-Jian Zhu, Qiang-Wei Wang, Li-Hua Sun, Zhi-Liang Wang, Kuan-Yu Wang, Guan-Zhang Li, Jian-Bao Xu, Chang-Yuan Ren, Wen-Ping Ma, Hong-Jun Wang, Zhao-Shi Bao
Publicado 2021

Predicting pain and function outcomes in people consulting with shoulder pain: the PANDA-S clinical cohort and qualitative study protocol

por Jeremy Lewis, Christian Mallen, Chris Littlewood, Danielle van der Windt, Edward Roddy, David Beard, Richard Riley, Tamar Pincus, Alison Hall, Simon Wathall, J L Rees, Johanna Cook, Benjamin Saunders, Gwenllian Wynne-Jones, Helen Myers, Adele Higginbottom, S Hennings, Milica Bucknall
Publicado 2021

Dual checkpoint blockade of CD47 and PD-L1 using an affinity-tuned bispecific antibody maximizes antitumor immunity

por Shahram Salek-Ardakani, Wenjing Yang, Sheng Ding, Shih-Hsun Chen, Pawel K Dominik, Jessica Stanfield, Nadia Kurd, Ryan Llewellyn, Jonathan Heyen, Carole Wang, Zea Melton, Thomas Van Blarcom, Kevin C Lindquist, Javier Chaparro-Riggers
Publicado 2021

Impact of stimulation among non-crying neonates with intact cord versus clamped cord on birth outcomes: observation study

por Shyam Sundar Budhathoki, Ashish KC, Nalini Singhal, Rejina Gurung, Srijana Sharma, Amit Bhandari, Susan Niermeyer, Leela Paudel, Jeevan Thapa, Omkar Basnet, Pratikshya Bhattarai, Ankit Acharya, Anjani Kumar Jha, Yasho Vardhan Pradhan, Sushil Nath Pyakurel, Kiran Bajracharya, Sheela Verma, Anjana KC Thapa, Krishna Prasad Bista, Jhalak Sharma Paudel, Sangita Khatri
Publicado 2021

Barriers and facilitators to accessing tuberculosis care in Nepal: a qualitative study to inform the design of a socioeconomic support intervention

por Olivia Biermann, Knut Lönnroth, S Bertel Squire, Maxine Caws, Tom Wingfield, Bhola Rai, Manoj Kumar Sah, Noemia Teixeira de Siqueira-Filha, Kritika Dixit, Tara Prasad Aryal, Gokul Mishra, Puskar Raj Paudel, Ram Narayan Pandit, Govinda Majhi, Jens Levy, Job van Rest, Suman Chandra Gurung, Raghu Dhital, Kristi Sidney
Publicado 2021

Deep brain stimulation for locomotion in incomplete human spinal cord injury (DBS-SCI): protocol of a prospective one-armed multi-centre study

por Michèle Hubli, Luca Regli, Anna-Sophie Hofer, Armin Curt, Martin Schubert, Thomas M Kessler, Christian R Baumann, Christian Meyer, Lennart H Stieglitz, Marc Bolliger, Markus F Oertel, Linard Filli, Romina Willi, Adrian Cathomen, Lukas Imbach, Iris Krüsi, Andrea Prusse, Martin E Schwab
Publicado 2021

Trans-arterial chemoembolization as a loco-regional inducer of immunogenic cell death in hepatocellular carcinoma: implications for immunotherapy.

por Vincenzo Mazzaferro, Federica Grillo, Pierluigi Toniutto, Petros Fessas, Francesco A Mauri, Teresa Marafioti, Ayse U Akarca, Alejandro Forner, Robert D Goldin, Alba Díaz, David J. Pinato, Sam M Murray, Takahiro Kaneko, Beatriz Mínguez, Valentina Cacciato, Claudio Avellini, Rosemary J. Boyton, Daniel M. Altmann, Edoardo Casagrande, Edoardo Giannini, Sherrie Bhoori
Publicado 2021

Insight into intraindividual variability across neuropsychological tests and its association with cognitive dysfunction in patients with lupus

por Dorcas Beaton, Jiandong Su, Marvin J Fritzler, Zahi Touma, Robin Green, Patricia Katz, Lesley Ruttan, Nicole Anderson, May Y Choi, Joan Wither, Dennisse Bonilla, Juan Pablo Díaz Martinez, Jennifer Wei He, Kathleen Bingham, Mahta Kakvan
Publicado 2021

Detection by fluorescence of pituitary neuroendocrine tumour (PitNET) tissue during endoscopic transsphenoidal surgery using bevacizumab-800CW (DEPARTURE trial): study protocol for...

por Wouter B Nagengast, J Marc C van Dijk, André P van Beek, Rob A Vergeer, Mark R Postma, Iris Schmidt, Astrid GW Korsten-Meijer, Robert A Feijen, Schelto Kruijff, Wilfred F A den Dunnen, Jos M A Kuijlen, Gerrit van den Berg
Publicado 2021