Bispecific antibody targeting TROP2xCD3 suppresses tumor growth of triple negative breast cancer

por Huicheng Liu, Lili Bai, Liu Huang, Na Ning, Yijia Li, Xuejiao Dong, Qiuyang Du, Minghui Xia, Yufei Chen, Likun Zhao, Yanhu Li, Qingwu Meng, Yaqi Duan, Jie Ming, Andy Qingan Yuan, Xiang-Ping Yang
Publicado 2021

Natural and cryptic peptides dominate the immunopeptidome of atypical teratoid rhabdoid tumors

por Martin Ebinger, Hans-Georg Rammensee, Juliane S Walz, Ana Marcu, Andreas Schlosser, Torsten Pietsch, Martin Schuhmann, Anne Keupp, Nico Trautwein, Pascal Johann, Matthias Wölfl, Johanna Lager, Camelia Maria Monoranu, Lisa M Henkel, Ulrich Wilhelm Thomale, Erdwine Klinker, Paul G Schlegel, Florian Oyen, Yair Reisner, Matthias Eyrich
Publicado 2021

Relationship between anaemia, coagulation parameters during pregnancy and postpartum haemorrhage at childbirth: a prospective cohort study

por Marian Knight, Saswati Sanyal Choudhury, Anjali Rani, Pramod Kumar, Farzana Zahir, Maria Quigley, Charles Opondo, Simon Stanworth, Michael Laffan, Jane Armitage, Anil Arora, Swapna D Kakoty, Colin Baigent, Shakuntala Chhabra, Dipika Deka, Gitanjali Deka, Pranabika Mahanta, Robin Medhi, Seeresha Rao, Indrani Roy, Carolin Solomi V, Ratna Kanta Talukdar, Nimmi Kansal
Publicado 2021

Adoptive cell therapy with tumor-infiltrating lymphocytes supported by checkpoint inhibition across multiple solid cancer types

por Marco Donia, Troels Holz Borch, Özcan Met, Julie Westerlin Kjeldsen, Morten Nielsen, Inge Marie Svane, Anders Handrup Kverneland, Christopher Aled Chamberlain, Sofie Kirial Mørk, Cathrine Lund Lorentzen, Lise Pyndt Jørgensen, Lene Buhl Riis, Christina Westmose Yde
Publicado 2021

Optimizing orthopedic trauma care delivery during the COVID-19 pandemic. A closed-loop audit of implementing a virtual fracture clinic and fast-track pathway in a Dutch level 2 tra...

por Dorien A Salentijn, Kristin A de Vries, Philou C W Noordman
Publicado 2021

Recovery, rehabilitation and follow-up services following critical illness: an updated UK national cross-sectional survey and progress report

por Ceri Battle, Anthony Bastin, Bronwen Connolly, Carl Waldmann, Joanne McPeake, Margaret Phillips, Martin Davies, Andrew Slack, Andrew Ferguson, Elizabeth Wilson, Greg Barton, Suzanne Bench, Dorothy Wade, Sarah Linford, Gordon Sturmey, Danielle Bear, Rhian Milton-Cole, Claire Adams, Jon Silversides, Penny Firshmann, Melanie Gager, Jack Parry-Jones, Helen Sanger
Publicado 2021

Combined inhibition of CXCL12 and PD-1 in MSS colorectal and pancreatic cancer: modulation of the microenvironment and clinical effects

por Dirk Jäger, Niels Halama, Jürgen Krauß, Nicolas Hohmann, Dirk Eulberg, Matthias Baumann, Anja Williams, Meggy Suarez-Carmona, Jutta Schreiber, Ulrike Pruefer, Anna Frömming, Diana Beyer, Jarf Ulf Jungelius, Aram Mangasarian
Publicado 2021

Protocol for the Stimulating β3-Adrenergic Receptors for Peripheral Artery Disease (STAR-PAD) trial: a double-blinded, randomised, placebo-controlled study evaluating the effects o...

por Clara Chow, Anthony C Keech, Laurent Billot, Sanjay Patel, Kristen J Bubb, Stuart M Grieve, Gemma A Figtree, Jonathan Golledge, Jason A Harmer, Meghan Finemore, Sarah Joy Aitken, Zara S Ali, Rebecca Mister, Michael P Gray, Naomi Hamburg, Vikram Puttaswamy
Publicado 2021

One chance to get it right: improving clinical handovers for better symptom control at the end of life

por Grace Ting, Katrin Sigurdardottir, Wojciech Leppert, Katarzyna Wolszczak, Vilma Tripodoro, Gabriel Goldraij, Martin Weber, Christina Gerlach, Lair Zambon, John Ellershaw, Catriona Mayland, Catriona Rachel Mayland, Dagny Faksvåg Haugen, Vilma Adriana Tripodoro, Melisa Aloisio, Sandra Analía Castro, Marit Irene Hansen, Eduardo Garcia Yanneo, Juliana Nalin Passarini, Ivete Bredda Saad
Publicado 2021

Healing Right Way: study protocol for a stepped wedge cluster randomised controlled trial to enhance rehabilitation services and improve quality of life in Aboriginal Australians a...

por Dominique A Cadilhac, Ivan Lin, Graeme J Hankey, Leon Flicker, Juli Coffin, Deborah Hersh, Erin Godecke, Natalie Ciccone, Meaghan McAllister, Tapan Rai, Colleen Hayward, Neil Drew, Deborah Woods
Publicado 2021

Beta-cell failure rather than insulin resistance is the major cause of abnormal glucose tolerance in Africans: insight from the Africans in America study

por Thomas Hormenu, Christopher W DuBose, Lilian S Mabundo, Joon Ha, Arthur Sherman, Anne E Sumner, M C Sage Ishimwe, Annemarie Wentzel, Elyssa M Shoup, Nana H Osei-Tutu, Arielle C Patterson, Hadi Bagheri
Publicado 2021

Determinants of losses in the latent tuberculosis infection cascade of care in Brazil

por Timothy Sterling, Alexandra Brito Souza, María B Arriaga, Gustavo Amorim, Mariana Araújo-Pereira, Betânia M F Nogueira, Artur T L Queiroz, Marina C Figueiredo, Michael S Rocha, Aline Benjamin, Adriana S R Moreira, Jamile G Oliveira, Valeria Rolla, Betina Durovni, José R Lapa e Silva, Afrânio L Kritski, Solange Cavalcante, Bruno B Andrade, Marcelo Cordeiro-Santos
Publicado 2021

Individually tailored self-management app-based intervention (selfBACK) versus a self-management web-based intervention (e-Help) or usual care in people with low back and neck pain...

por Tom Ivar Lund Nilsen, Paul Jarle Mork, Solveig Osborg Ose, Silje Lill Kaspersen, Gunn Hege Marchand, Anne Lovise Nordstoga, Anna Marcuzzi, Kerstin Bach, Gro Falkener Bertheussen, Ilya Ashikhmin, Nora Østbø Boldermo, Else-Norun Kvarner, Lene Aasdahl, Ellen Marie Bardal, Janne-Birgitte Børke, Sigmund Gismervik
Publicado 2021

Evaluating associations of joint swelling, joint stiffness and joint pain with physical activity in first-degree relatives of patients with rheumatoid arthritis: Studies of the Aet...

por Michael H Weisman, Joachim H Ix, Jill M Norris, James R ODell, Ted R Mikuls, Kevin D Deane, V Michael Holers, M Kristen Demoruelle, Jane H Buckner, Richard M Keating, Jan M Hughes-Austin, Samuel R Ward
Publicado 2021

SYMptom monitoring with Patient-Reported Outcomes using a web application among patients with Lung cancer in the Netherlands (SYMPRO-Lung): study protocol for a stepped-wedge rando...

por Bregje D Onwuteaka-Philipsen, Lonneke van de Poll-Franse, Neil K Aaronson, Iris Walraven, Harm-Jan Bogaard, Jacqueline G Hugtenburg, Nicole E Billingy, Vashti N M F Tromp, Evalien Veldhuijzen, Jose Belderbos, Esther Feldman, Corina J G van den Hurk, Annemarie Becker-Commissaris, Rianne J A Hoek
Publicado 2021

European knowledge alliance for innovative measures in prevention of work-related musculoskeletal pain disorders (Prevent4Work Project): protocol for an international mixed-methods...

por Thorvaldur Skuli Palsson, Allan Riis, Pablo Herrero, Pablo Bellosta-Lopez, Victor Domenech-Garcia, Francesco Langella, Steffan Wittrup Christensen, Pedro Berjano, Priscila de Brito Silva, Palle Schlott Jensen, Alice Baroncini, Julia Blasco-Abadía, Carolina Jiménez-Sánchez, Sandra Calvo, Diego Jaén-Carrillo, Morten Hoegh
Publicado 2021

Impact on Mental, Physical and Cognitive functioning of a Critical care sTay during the COVID-19 pandemic (IMPACCT COVID-19): protocol for a prospective, multicentre, mixed-methods...

por Felipe González-Seguel, Agustín Camus-Molina, Jaime Leppe, Ana Cristina Castro-Avila, Catalina Merino-Osorio, Ana Castro-Ávila, Camilo Cáceres Parra, Eduardo González Tapia, Felipe Muñoz-Muñoz, Fernanda Baus Auil, Javiera Aguilera Scarpati, Joaquín Olave, Macarena Leiva-Corvalán, Pilar Castro, Yerko Villagra Jofré
Publicado 2021

Suboptimal diabetic control and psychological burden after the triple disaster in Japan: the Fukushima Health Management Survey

por Mitsuaki Hosoya, Masanori Nagao, Atsushi Takahashi, Hiromasa Ohira, Tetsuya Ohira, Michio Shimabukuro, Seiji Yasumura, Masaharu Maeda, Mayumi Harigane, Yuriko Suzuki, Hirooki Yabe, Hironori Nakano, Kenji Kamiya, Akira Sakai, Hiroyuki Hirai, Kanako Okazaki, Fumikazu Hayashi, Junichiro James Kazama, Hitoshi Ohto
Publicado 2021

Treatment of early-stage breast cancer with percutaneous thermal ablation, an open-label randomised phase 2 screening trial: rationale and design of the THERMAC trial

por Erwin Birnie, Cornelis Verhoef, Reno Debets, Taco M A L Klem, Adriaan Moelker, Elles M F van de Voort, Gerson M Struik, Linetta B Koppert, Glenn Yo, Maura J P V Macco, Renata H J A Sinke, Martine Franckena
Publicado 2021

Relationship between food insecurity and smoking status among women living with and at risk for HIV in the USA: a cohort study

por Edward A Frongillo, Adaora A Adimora, Sheri D Weiser, Janet M Turan, Mardge Cohen, Elise D Riley, Daniel Merenstein, Lila A Sheira, Judith Hahn, Kartika Palar, Tracey E Wilson, Eryka L Wentz, Ighovwerha Ofotokun, Lisa Metsch, Phyllis C Tien
Publicado 2021