Excess burden of age-associated comorbidities among people living with HIV in British Columbia, Canada: a population-based cohort study

por Taylor McLinden, Julio S G Montaner, Robert S Hogg, Ni Gusti Ayu Nanditha, Adrianna Paiero, Hiwot M Tafessu, Martin St-Jean, Jacek Kopec, Viviane D Lima
Publicado 2021

Impact of pregnancy and risk factors for ventricular arrhythmias in women with tetralogy of Fallot

por Mette E Estensen, Helge Skulstad, Thor Edvardsen, Oyvind H Lie, Kristina Haugaa, Alessia Quattrone, Eirik Nestaas, Charlotte de Lange, Kirsti Try, Harald L Lindberg
Publicado 2021

Are patients’ goals in treatment associated with expected treatment outcomes? Findings from a mixed-methods study on outpatient pharmacological treatment for opioid use disorder

por Brittany B Dennis, Andrew Worster, Launette Rieb, David C Marsh, Tea Rosic, Leen Naji, Darren B Chai
Publicado 2021

Nurse-led PrEP-RN clinic: a prospective cohort study exploring task-Shifting HIV prevention to public health nurses

por Patrick O'Byrne, Amanda Vandyk, Lauren Orser, Marlene Haines
Publicado 2021

Patency of arterial repairs from wartime extremity vascular injuries

por Lauren J Haney, Esther Bae, Mary Jo V Pugh, Laurel A Copeland, Chen-Pin Wang, Daniel J MacCarthy, Megan E Amuan, Paula K Shireman
Publicado 2020

Tumor-draining lymph node is important for a robust abscopal effect stimulated by radiotherapy

por David Lawson, Zachary S Buchwald, Tahseen H Nasti, Judong Lee, Christiane S Eberhardt, Se Jin Im, Walter Curran, Rafi Ahmed, Mohammad K Khan, Andreas Wieland
Publicado 2020

CHILD-BRIGHT READYorNot Brain-Based Disabilities Trial: protocol of a randomised controlled trial (RCT) investigating the effectiveness of a patient-facing e-health intervention de...

por Sarah Gander, Sarah Zaidi, Andrew Mackie, Roger Stoddard, Myla E Moretti, Lonnie Zwaigenbaum, Wendy J Ungar, Khush Amaria, Adrienne Kovacs, Ronen Rozenblum, Barbara Galuppi, Linda Nguyen, Sonya Strohm, Nadilein Mahlberg, Alicia Via-Dufresne Ley, Ariane Marelli, Donna Thomson, JoAnne Mosel, Connie Putterman, Kinga Pozniak, Nathan Tasker, Julia Hanes, Kyle Chambers, Jessica Havens, Claire Dawe-McCord, Dana Arafeh, Hana Alazem, John Andersen, Kerry Boyd, Caitlin Cassidy, Jamie Churchill, CJ Curran, Anne Fournier, Anna McCormick, Ronit Mesterman, Maryam Oskoui, Janet Rennick, Jordan Sheriko, Kathy Speechley, Kelly Wynne, Fabiola Breault, Yomna Elshamy, Rocio Gutierrez, Hashaam Hasan, Rhiannon Hicks, André Pépin, Rochelle Sorzano, Jennifer Zwicker
Publicado 2021

Clinical impact of COVID-19 on patients with cancer treated with immune checkpoint inhibition

por Dirk Schadendorf, Lisa Zimmer, Serigne Lo, Caroline Robert, John Haanen, Ines Pires da Silva, Paolo Antonio Ascierto, Reinhard Dummer, Michael Manos, Joanna Mangana, Richard D Carvajal, Georgina V Long, Alon Vaisman, Christian Posch, Paola Queirolo, Axel Hauschild, Christian U Blank, Maria Grazia Vitale, Carlo Alberto Tondini, Arielle Elkrief, Karijn P M Suijkerbuijk, Mario Mandala, Alexander M Menzies, Aljosja Rogiers, Chiara Tentori, Joseph M Grimes, Megan H Trager, Sharon Nahm, Peter Bowling, Neha Papneja, April A N Rose, Jessica S W Borgers, Severine Roy, Thiago Pimentel Muniz, Tim Cooksley, Jeremy Lupu, Samuel D Saibil, Matteo S Carlino, Michael Erdmann, Laura Pala, Wilson H Miller Jr, Osama E Rahma, Paul C Lorigan
Publicado 2021

IL-21 arming potentiates the anti-tumor activity of an oncolytic vaccinia virus in monotherapy and combination therapy

por Xiaoyan Zhang, Chen Zhao, Tianyue Chen, Xiangqing Ding, Qibin Liao, Nan Gao, Jianqing Xu
Publicado 2021

Cardiovascular risk prediction using physical performance measures in COPD: results from a multicentre observational study

por Divya Mohan, Carmel M McEniery, John R Cockcroft, William MacNee, Jonathan Fuld, Marie Fisk, Joseph Cheriyan, Ruth Tal-Singer, Ian B Wilkinson, Jilles M Fermont, Hana Müllerova, Angela M Wood, Charlotte E Bolton, Kaisa M Mäki-Petäjä, Ali B Al-Hadithi
Publicado 2020

SARS-CoV-2 infection and adverse events in patients with cancer receiving immune checkpoint inhibitors: an observational prospective study

por Paolo Antonio Ascierto, Eliana Rulli, Anna Cecilia Bettini, Maria Grazia Vitale, Carlo Alberto Tondini, Matilde De Luca, Barbara Merelli, Mario Mandala, Sharon Nahm, Paul Lorigan, Andrea Bianchetti, Lucia Bonomi, Giorgia Negrini, Andrea Di Croce
Publicado 2021

MUC1-C integrates activation of the IFN-γ pathway with suppression of the tumor immune microenvironment in triple-negative breast cancer

por Kwok-Kin Wong, Song Liu, Qiang Hu, Mark Long, Donald Kufe, Nami Yamashita, Atsushi Fushimi, Masaaki Yamamoto, Tsuyoshi Hata, Masayuki Hagiwara, Atrayee Bhattacharya
Publicado 2021

Estrogen receptor beta signaling in CD8+ T cells boosts T cell receptor activation and antitumor immunity through a phosphotyrosine switch

por Jing Yang, Rong Li, Bin Yuan, Curtis A Clark, Bogang Wu, Justin M Drerup, Tianbao Li, Victor X Jin, Yanfen Hu, Tyler J Curiel
Publicado 2021

Tisagenlecleucel infusion in patients with relapsed/refractory ALL and concurrent serious infection

por Weijie Li, Keith J August, Erin M Hall, Dwight E Yin, Rakesh K Goyal, Atif A Ahmed, Grace S Mitchell, Shawn D St. Peter, Terrie G Flatt, Ibrahim A Ahmed, Richard J Hendrickson, G Doug Myers
Publicado 2021

Impact of C-reactive protein flare-response on oncological outcomes in patients with metastatic renal cell carcinoma treated with nivolumab

por Toshiki Kijima, Shohei Fukuda, Kazutaka Saito, Yosuke Yasuda, Soichiro Yoshida, Minato Yokoyama, Junichiro Ishioka, Yoh Matsuoka, Yukio Kageyama, Yasuhisa Fujii
Publicado 2021

Examining the impacts of the COVID-19 pandemic on family mental health in Canada: findings from a national cross-sectional study

por Anne C Gadermann, Kimberly C Thomson, Chris G Richardson, Monique Gagné, Corey McAuliffe, Saima Hirani, Emily Jenkins
Publicado 2021

Blocking IL-17A enhances tumor response to anti-PD-1 immunotherapy in microsatellite stable colorectal cancer

por Chao Liu, Yang Yao, Jiaqi Shi, Ruiqi Liu, Bojun Wang, Jie Lian, Haoxiu Sun, Chunhui Zhang, Lin Fang, Xin Guan, Shuling Han, Fei Zhan, Shengnan Luo, Yuanfei Yao, Tongsen Zheng, Yanqiao Zhang
Publicado 2021

Guselkumab, an inhibitor of the IL-23p19 subunit, provides sustained improvement in signs and symptoms of active psoriatic arthritis: 1 year results of a phase III randomised study...

por Atul Deodhar, Shihong Sheng, Philip S Helliwell, Soumya D Chakravarty, Elizabeth C Hsia, Enrique R Soriano, Chetan S Karyekar, Wolf-Henning Boehncke, Prasheen Agarwal, Alexa P Kollmeier, Federico Zazzetti, Ramanand A Subramanian, Xie L Xu, Qing C Zuraw, Yusang Jiang, Bei Zhou, Yanli Zhuang, May Shawi
Publicado 2021