In vivo pharmacokinetic enhancement of monomeric Fc and monovalent bispecific designs through structural guidance

por Lu Shan, Nydia Van Dyk, Nantaporn Haskins, Kimberly M. Cook, Kim L. Rosenthal, Ronit Mazor, Sonia Dragulin-Otto, Yu Jiang, Herren Wu, William F. Dall’Acqua, Martin J. Borrok, Melissa M. Damschroder, Vaheh Oganesyan
Publicado 2021

Membrane anchoring facilitates colocalization of enzymes in plant cytochrome P450 redox systems

por Tomas Laursen, Hiu Yue Monatrice Lam, Kasper Kildegaard Sørensen, Pengfei Tian, Cecilie Cetti Hansen, Jay T. Groves, Knud Jørgen Jensen, Sune M. Christensen
Publicado 2021

Frontoparietal network resilience is associated with protection against cognitive decline in Parkinson’s disease

por Arianna D. Cascone, Stephanie Langella, Miriam Sklerov, Eran Dayan
Publicado 2021

Connectivity of EEG synchronization networks increases for Parkinson’s disease patients with freezing of gait

por Eitan E. Asher, Meir Plotnik, Moritz Günther, Shay Moshel, Orr Levy, Shlomo Havlin, Jan W. Kantelhardt, Ronny P. Bartsch
Publicado 2021

Pulmonary immune cell trafficking promotes host defense against alcohol-associated Klebsiella pneumonia

por Derrick R. Samuelson, Min Gu, Judd E. Shellito, Patricia E. Molina, Christopher M. Taylor, Meng Luo, David A. Welsh
Publicado 2021

Functionnectome as a framework to analyse the contribution of brain circuits to fMRI

por Victor Nozais, Stephanie J. Forkel, Chris Foulon, Laurent Petit, Michel Thiebaut de Schotten
Publicado 2021

Altered theta rhythm and hippocampal-cortical interactions underlie working memory deficits in a hyperglycemia risk factor model of Alzheimer’s disease

por Ryan. A. Wirt, Lauren. A. Crew, Andrew. A. Ortiz, Adam. M. McNeela, Emmanuel Flores, Jefferson. W. Kinney, James M. Hyman
Publicado 2021

Campylobacter jejuni genotypes are associated with post-infection irritable bowel syndrome in humans

por Stephanie Peters, Ben Pascoe, Zuowei Wu, Sion C. Bayliss, Ximin Zeng, Adam Edwinson, Sakteesh Veerabadhran-Gurunathan, Selina Jawahir, Jessica K. Calland, Evangelos Mourkas, Robin Patel, Terra Wiens, Marijke Decuir, David Boxrud, Kirk Smith, Craig T. Parker, Gianrico Farrugia, Qijing Zhang, Samuel K. Sheppard, Madhusudan Grover
Publicado 2021

Modulation of Toll-like receptor 1 intracellular domain structure and activity by Zn2+ ions

por Vladislav A. Lushpa, Marina V. Goncharuk, Cong Lin, Arthur O. Zalevsky, Irina A. Talyzina, Aleksandra P. Luginina, Daniil D. Vakhrameev, Mikhail B. Shevtsov, Sergey A. Goncharuk, Alexander S. Arseniev, Valentin I. Borshchevskiy, Xiaohui Wang, Konstantin S. Mineev
Publicado 2021

The structure of a dimeric form of SARS-CoV-2 polymerase

por Florian A. Jochheim, Dimitry Tegunov, Hauke S. Hillen, Jana Schmitzová, Goran Kokic, Christian Dienemann, Patrick Cramer
Publicado 2021

Ultrastructural analysis in yeast reveals a meiosis-specific actin-containing nuclear bundle

por Tomoko Takagi, Masako Osumi, Akira Shinohara
Publicado 2021

Interactions between temperature and energy supply drive microbial communities in hydrothermal sediment

por Lorenzo Lagostina, Søs Frandsen, Barbara J. MacGregor, Clemens Glombitza, Longhui Deng, Annika Fiskal, Jiaqi Li, Mechthild Doll, Sonja Geilert, Mark Schmidt, Florian Scholz, Stefano Michele Bernasconi, Bo Barker Jørgensen, Christian Hensen, Andreas Teske, Mark Alexander Lever
Publicado 2021

Retraction Note: A biomimetic assay platform for the interrogation of antigen-dependent anti-tumor T-cell function

por Jeremy To, Doug Quackenbush, Emily Rowell, Lilin Li, Connor Reed, Frederick Lo, Shane R. Horman
Publicado 2021

Association between polygenic propensity for psychiatric disorders and nutrient intake

por Avina K. Hunjan, Christopher Hübel, Yuhao Lin, Thalia C. Eley, Gerome Breen
Publicado 2021

Author Correction: CHIMs are versatile cholesterol analogs mimicking and visualizing cholesterol behavior in lipid bilayers and cells

por Anna L. L. Matos, Fabian Keller, Tristan Wegner, Carla Elizabeth Cadena del Castillo, David Grill, Sergej Kudruk, Anne Spang, Frank Glorius, Andreas Heuer, Volker Gerke
Publicado 2021

Neutrophil azurophilic granule glycoproteins are distinctively decorated by atypical pauci- and phosphomannose glycans

por Karli R. Reiding, Yu-Hsien Lin, Floris P. J. van Alphen, Alexander B. Meijer, Albert J. R. Heck
Publicado 2021

Phase separation of Epstein-Barr virus EBNA2 protein reorganizes chromatin topology for epigenetic regulation

por Yiting Yang, Xidong Ye, Ranran Dai, Zhaoqiang Li, Yan Zhang, Wei Xue, Yongchang Zhu, Delong Feng, Litao Qin, Xin Wang, Bo Lei, Shixiu Liao, Bingtao Hao
Publicado 2021

The endosomal Q-SNARE, Syntaxin 7, defines a rapidly replenishing synaptic vesicle recycling pool in hippocampal neurons

por Yasunori Mori, Koh-ichiro Takenaka, Yugo Fukazawa, Shigeo Takamori
Publicado 2021

Comprehensive in situ mapping of human cortical transcriptomic cell types

por Christoffer Mattsson Langseth, Daniel Gyllborg, Jeremy A. Miller, Jennie L. Close, Brian Long, Ed S. Lein, Markus M. Hilscher, Mats Nilsson
Publicado 2021

14-3-3 proteins inactivate DAPK2 by promoting its dimerization and protecting key regulatory phosphosites

por Matej Horvath, Olivia Petrvalska, Petr Herman, Veronika Obsilova, Tomas Obsil
Publicado 2021