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  1. 20101
    Improved eIF4E binding peptides by phage display guided design: plasticity of interacting surfaces yield collective effects.
    “...Eukaryotic initiation factor (eIF)4E is over-expressed in many types of cancer such as breast, head...”
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  2. 20102
    Characterizing the network of drugs and their affected metabolic subpathways.
    “... close drug-disease associations such as sex hormone drugs and cancer suggesting drug dual effects...”
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  3. 20103
    SFRP2 and slug contribute to cellular resistance to apoptosis in hypertrophic scars.
    “... cell apoptosis, in vitro and in vivo, and SFRP2 regulates the expression of Slug in cervical cancer...”
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  4. 20104
    An integrated in silico approach to design specific inhibitors targeting human poly(a)-specific ribonuclease.
    “... that PARN can be used as potent and promising anti-cancer target. In the present study, we attempt...”
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  5. 20105
    Role of Smad proteins in resistance to BMP-induced growth inhibition in B-cell lymphoma.
    “...Bone morphogenetic protein (BMP) expression and signaling are altered in a variety of cancers...”
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  6. 20106
    Selective histonedeacetylase inhibitor M344 intervenes in HIV-1 latency through increasing histone acetylation and activation of NF-kappaB.
    “... and achieve a cure. M344, a novel HDAC inhibitor, shows robust activity in a variety of cancer cells...”
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  7. 20107
    SIGNIFICANCE OF SINGLE-NUCLEOTIDE POLYMORPHISMS 2578C>A AND +936C>T IN THE VEGF GENE FOR EFFICIENCY EVALUAT ION OF ANTICANCER IMMUNOTHERAPY IN PAT IENTS WITH METASTAT IC SKIN MELANOMA
    “...Abstract. Increased VEGF levels in cancer patients may be associated with decreased number...”
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  8. 20108
    Cell survival signalling through PPARδ and arachidonic acid metabolites in neuroblastoma.
    “...Retinoic acid (RA) has paradoxical effects on cancer cells: promoting cell death, differentiation...”
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  9. 20109
    Protein kinase R modulates c-Fos and c-Jun signaling to promote proliferation of hepatocellular carcinoma with hepatitis C virus infection.
    “... with siRNA and a PKR expression plasmid, and cancer-related genes were assessed by real-time PCR and Western...”
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  10. 20110
    Dietary heme-mediated PPARα activation does not affect the heme-induced epithelial hyperproliferation and hyperplasia in mouse colon.
    “...Red meat consumption is associated with an increased colon cancer risk. Heme, present in red meat...”
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  11. 20111
    Interferon-α-conditioned human monocytes combine a Th1-orienting attitude with the induction of autologous Th17 responses: role of IL-23 and IL-12.
    “...IFN-α exerts multiple effects leading to immune protection against pathogens and cancer as well...”
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  12. 20112
    Frequent and simultaneous epigenetic inactivation of TP53 pathway genes in acute lymphoblastic leukemia.
    “... implicated in cancer in a group of ALL samples at diagnosis (n = 48). We found that 154 genes were methylated...”
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  13. 20113
    Lack of infection with XMRV or other MLV-related viruses in blood, post-mortem brains and paternal gametes of autistic individuals.
    “...) and in prostate cancer by several, though not all studies.<h4>Methodology/principal findings</h4>We assessed...”
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  14. 20114
    Adoptive transfer of siRNA Cblb-silenced CD8+ T lymphocytes augments tumor vaccine efficacy in a B16 melanoma model.
    “... as add-on adjuvant therapy to augment the efficacy of existing cancer immunotherapy regimens in clinical...”
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  15. 20115
    In vitro and in vivo antitumor activity of a novel pH-activated polymeric drug delivery system for doxorubicin.
    “... cancer models) and HepG2 (hepatocellular carcinoma model) cell lines. Following the in vitro results, we...”
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  16. 20116
    prox1b Activity is essential in zebrafish lymphangiogenesis.
    “..., inflammation and cancer metastasis, and may ultimately contribute to novel therapies....”
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  17. 20117
    Evolutionary history of tissue kallikreins.
    “... of prostate cancer. The KLK gene family encompasses the largest contiguous cluster of serine proteases...”
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  18. 20118
    Cyclin-dependent kinase 6 phosphorylates NF-κB P65 at serine 536 and contributes to the regulation of inflammatory gene expression.
    “... proliferation, inflammation and cancer. Using an unbiased approach we identified human CDK6 as a novel kinase...”
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  19. 20119
    Vincristine chemotherapy trials and pharmacokinetics in tasmanian devils with tasmanian devil facial tumor disease.
    “...Tasmanian Devil Facial Tumor Disease (DFTD) is a transmissible cancer threatening to cause...”
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  20. 20120
    A feedback inhibition between miRNA-127 and TGFβ/c-Jun cascade in HCC cell migration via MMP13.
    por Zhihong Yang, Yuxia Zhang, Li Wang
    Publicado 2013
    “...Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide and is increasing...”
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