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22801por Miao Tian, Xiumei Wang, Jihong Sun, Wenlong Lin, Lumin Chen, Shengduo Liu, Ximei Wu, Liyun Shi, Pinglong Xu, Xiujun Cai, Xiaojian Wang“...The alternative mechanisms of innate immunity in tumorigenesis of colorectal cancers are unclear...”
Publicado 2020
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22802por Ruilong Liu, Wenfeng Li, Bangbao Tao, Xiongjun Wang, Zhuo Yang, Yajuan Zhang, Chenyao Wang, Rongzhi Liu, Hong Gao, Ji Liang, Weiwei Yang“...6-phosphogluconate dehydrogenase is commonly upregulated in cancers. Here, the authors show...”
Publicado 2019
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22803“... with cancerous and invasive lesions. Prevalence of cancerous lesion was 0.22%. Abnormal histologic results were...”
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22804por Zhenfang Du, Benjamin P. Brown, Soyeon Kim, Donna Ferguson, Dean C. Pavlick, Gowtham Jayakumaran, Ryma Benayed, Jean-Nicolas Gallant, Yun-Kai Zhang, Yingjun Yan, Monica Red-Brewer, Siraj M. Ali, Alexa B. Schrock, Ahmet Zehir, Marc Ladanyi, Adam W. Smith, Jens Meiler, Christine M. Lovly“... occurs in other ErbB receptors in multiple cancers, and characterize the mechanism and inhibition of EGFR...”
Publicado 2021
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22805por Octavio A. Romero, Andrea Vilarrubi, Juan J. Alburquerque-Bejar, Antonio Gomez, Alvaro Andrades, Deborah Trastulli, Eva Pros, Fernando Setien, Sara Verdura, Lourdes Farré, Juan F. Martín-Tejera, Paula Llabata, Ana Oaknin, Maria Saigi, Josep M. Piulats, Xavier Matias-Guiu, Pedro P. Medina, August Vidal, Alberto Villanueva, Montse Sanchez-Cespedes“...SMARCA4 is commonly inactivated in lung and ovarian cancers. Here the authors show that SMARCA4...”
Publicado 2021
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22806por Sandrine Guillard, Paulina Kolasinska-Zwierz, Judit Debreczeni, Jason Breed, Jing Zhang, Nicolas Bery, Rose Marwood, Jon Tart, Ross Overman, Pawel Stocki, Bina Mistry, Christopher Phillips, Terence Rabbitts, Ronald Jackson, Ralph Minter“...Ras is mutated in many cancers, but so far no drug targeting Ras is in clinical use despite great...”
Publicado 2017
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22807por Wenjing Li, Xiaoyang Gu, Chunhong Liu, Yanyan Shi, Pan Wang, Na Zhang, Rui Wu, Liang Leng, Bingteng Xie, Chen Song, Mo Li“...Mutations in the BARD1 gene have been identified as risk factors in breast and ovarian cancers...”
Publicado 2021
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22808por Zhaleh Safikhani, Petr Smirnov, Kelsie L. Thu, Jennifer Silvester, Nehme El-Hachem, Rene Quevedo, Mathieu Lupien, Tak W. Mak, David Cescon, Benjamin Haibe-Kains“...Altered mRNA splicing features in many cancers, but it has not been linked to drug response. Here...”
Publicado 2017
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22809por Ling-Wen Ding, Qiao-Yang Sun, Jarem J. Edwards, Lucia Torres Fernández, Xue-Bin Ran, Si-Qin Zhou, Richard A. Scolyer, James S. Wilmott, John F. Thompson, Ngan Doan, Jonathan W. Said, Nachiyappan Venkatachalam, Jin-Fen Xiao, Xin-Yi Loh, Maren Pein, Liang Xu, David W. Mullins, Henry Yang, De-Chen Lin, H. Phillip Koeffler“...LNK is a tumor suppressor in hematopoietic cancers, but its function in melanoma is unclear. Here...”
Publicado 2019
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22810Moss enables high sensitivity single-nucleotide variant calling from multiple bulk DNA tumor samples“... that can leverage multiple samples to improve somatic variant calling in different cancers....”
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22811
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22812por Sophie Altamirano, Zhongming Li, Man Shun Fu, Minna Ding, Sophie R. Fulton, J. Marina Yoder, Vy Tran, Kirsten Nielsen“... Dysregulation of the cell cycle underlies many human genetic diseases and cancers, yet numerous...”
Publicado 2021
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22813por Megan M. Monsanto, Bingyan J. Wang, Zach R. Ehrenberg, Oscar Echeagaray, Kevin S. White, Roberto Alvarez, Kristina Fisher, Sharon Sengphanith, Alvin Muliono, Natalie A. Gude, Mark A. Sussman“... rivals most cancers. Here, the authors describe an approach to control and pattern 3 distinct human...”
Publicado 2020
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22814por Megan J. Bywater, Deborah L. Burkhart, Jasmin Straube, Arianna Sabò, Vera Pendino, James E. Hudson, Gregory A. Quaife-Ryan, Enzo R. Porrello, James Rae, Robert G. Parton, Theresia R. Kress, Bruno Amati, Trevor D. Littlewood, Gerard I. Evan, Catherine H. Wilson“...Levels of the transcription factor Myc are deregulated in a range of different cancers. Here...”
Publicado 2020
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22815por Shuheng Lin, Ana Negulescu, Sirisha Bulusu, Benjamin Gibert, Jean-Guy Delcros, Benjamin Ducarouge, Nicolas Rama, Nicolas Gadot, Isabelle Treilleux, Pierre Saintigny, Olivier Meurette, Patrick Mehlen“...Notch signalling is deregulated in several cancers; therefore, strategies targeting this pathway...”
Publicado 2017
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22816por Daniel P. Duarte, Allan J. Lamontanara, Giuseppina La Sala, Sukyo Jeong, Yoo-Kyoung Sohn, Alejandro Panjkovich, Sandrine Georgeon, Tim Kükenshöner, Maria J. Marcaida, Florence Pojer, Marco De Vivo, Dmitri Svergun, Hak-Sung Kim, Matteo Dal Peraro, Oliver Hantschel“...Constitutive Btk signaling drives several B-cell cancers. Here the authors demonstrate key...”
Publicado 2020
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22817por Vivek Bhaskaran, Michal O. Nowicki, Mahmoud Idriss, Miguel A. Jimenez, Gianmarco Lugli, Josie L. Hayes, Ahmad Bakur Mahmoud, Rachel E. Zane, Carmela Passaro, Keith L. Ligon, Daphne Haas-Kogan, Agnieszka Bronisz, Jakub Godlewski, Sean E. Lawler, E. Antonio Chiocca, Pierpaolo Peruzzi“...The delivery of single therapeutic microRNAs in brain cancers is challenging. Here, the authors...”
Publicado 2019
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22818por Ingeborg Menzl, Tinghu Zhang, Angelika Berger-Becvar, Reinhard Grausenburger, Gerwin Heller, Michaela Prchal-Murphy, Leo Edlinger, Vanessa M. Knab, Iris Z. Uras, Eva Grundschober, Karin Bauer, Mareike Roth, Anna Skucha, Yao Liu, John M. Hatcher, Yanke Liang, Nicholas P. Kwiatkowski, Daniela Fux, Andrea Hoelbl-Kovacic, Stefan Kubicek, Junia V. Melo, Peter Valent, Thomas Weichhart, Florian Grebien, Johannes Zuber, Nathanael S. Gray, Veronika Sexl“...Cyclin-dependent kinases are deregulated in blood cancers. Here, the authors show that CDK8...”
Publicado 2019
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22819por Shruti Sharma, Antonio Carmona, Agnieszka Skowronek, Fangyan Yu, Mark O. Collins, Sindhu Naik, Claire M. Murzeau, Pei-Li Tseng, Kai S. Erdmann“... on the cell surface in many cancers. Here, Sharma et al. show that endosome associated trafficking regulator...”
Publicado 2019
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22820por M. D. Lynch, C. N. S. Lynch, E. Craythorne, K. Liakath-Ali, R. Mallipeddi, J. N. Barker, F. M. Watt“...Deep sequencing technologies allow for the investigation of clonal evolution in human cancers. Here...”
Publicado 2017
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