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  1. 5401
    Analysis of somatic mutations across the kinome reveals loss-of-function mutations in multiple cancer types
    por Runjun D. Kumar, Ron Bose
    Publicado 2017
    “...Abstract In this study we use somatic cancer mutations to identify important functional residues...”
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  2. 5402
    Evidence for the importance of post-transcriptional regulatory changes in ovarian cancer progression and the contribution of miRNAs
    “... expression over cancer development but the functional significance of these changes often rests upon...”
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  3. 5403
    Single-cell profiling of tumor heterogeneity and the microenvironment in advanced non-small cell lung cancer
    “... in non-small cell lung cancer (NSCLC). Here, the authors profile 42 late-stage NSCLC patients with single...”
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  4. 5404
    Targeting nucleotide metabolism enhances the efficacy of anthracyclines and anti-metabolites in triple-negative breast cancer
    Materias: “...Neoplasms. Tumors. Oncology. Including cancer and carcinogens...”
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  5. 5405
    Edelfosine nanoemulsions inhibit tumor growth of triple negative breast cancer in zebrafish xenograft model
    “...Abstract Triple negative breast cancer (TNBC) is known for being very aggressive, heterogeneous...”
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  6. 5406
    Author Correction: Crizotinib-induced immunogenic cell death in non-small cell lung cancer
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  7. 5407
    Valerian and valeric acid inhibit growth of breast cancer cells possibly by mediating epigenetic modifications
    “... that the circadian-related herb valerian can inhibit breast cancer cell growth and explored epigenetic changes...”
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  8. 5408
    Local mutational diversity drives intratumoral immune heterogeneity in non-small cell lung cancer
    “... cancer patients' biopsies and find high spatial immune heterogeneity with local mutational burden...”
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  9. 5409
    Acetylation of KLF5 maintains EMT and tumorigenicity to cause chemoresistant bone metastasis in prostate cancer
    “...The therapies for bone metastatic prostate cancer are limited and the underlying mechanisms...”
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  10. 5410
    mTOR, metabolism, and the immune response in HPV-positive head and neck squamous cell cancer
    por Joseph D. Coppock, John H. Lee
    Publicado 2016
    “... therapeutic utility of mTOR inhibitors in the treatment of these cancers. Numerous clinical studies have begun...”
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  11. 5411
    Prognostic value of a 25-gene assay in patients with gastric cancer after curative resection
    “... and chemotherapy benefit prediction compared with conventional staging in Gastric cancer (GC). Twenty-three...”
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  12. 5412
    A functionally significant SNP in TP53 and breast cancer risk in African-American women
    Materias: “...Neoplasms. Tumors. Oncology. Including cancer and carcinogens...”
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  13. 5413
    Expressional analysis of disease-relevant signalling-pathways in primary tumours and metastasis of head and neck cancers
    “...-induced transcriptional modulation, and the recruitment of cancer associated fibroblasts, ultimately...”
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  14. 5414
    Blockade of Axl signaling ameliorates HPV16E6-mediated tumorigenecity of cervical cancer
    “... cancers. Axl expression was markedly higher in human papilloma virus type 16E6 (HPV16E6)-overexpressing...”
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  15. 5415
    [2] Neoadjuvant intravesical chemotherapy to treat extended large non-muscle-invasive bladder cancer
    “... in the treatment of large exophytic bladder tumours. About 75% of bladder cancers are superficial at diagnosis...”
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  16. 5416
    Regulation of CHK1 by mTOR contributes to the evasion of DNA damage barrier of cancer cells
    “... of mTORC1 signaling by DNA damage is abrogated in many cancer cells, thus mTORC1 signaling remains active...”
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  17. 5417
    Aptamer-mediated survivin RNAi enables 5-fluorouracil to eliminate colorectal cancer stem cells
    “...Abstract The development of chemoresistance and inability in elimination of cancer stem cells...”
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  18. 5418
    VGLL4 Selectively Represses YAP-Dependent Gene Induction and Tumorigenic Phenotypes in Breast Cancer
    “... proposed to regulate key signaling networks involved in cancer development and progression. However...”
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  19. 5419
    Generation of sphingosine-1-phosphate is enhanced in biliary tract cancer patients and is associated with lymphatic metastasis
    “...Abstract Lymphatic metastasis is known to contribute to worse prognosis of biliary tract cancer...”
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  20. 5420
    Aurora kinase A (AURKA) interaction with Wnt and Ras-MAPK signalling pathways in colorectal cancer
    “... knockdown in two colorectal cancer (CRC) cell lines with 20q gain and AURKA overexpression. Next, using...”
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