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  1. 15821
    Genome-wide association study identifies novel susceptibility loci for cutaneous squamous cell carcinoma
    “...Cutaneous squamous cell carcinoma is the second most common type of skin cancer. In this genome...”
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  2. 15822
    A novel Fer/FerT targeting compound selectively evokes metabolic stress and necrotic death in malignant cells
    “...The tyrosine-kinases Fer/FerT associate with the mitochondrial electron transport chain in cancer...”
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  3. 15823
    Comprehensive transcriptomic analysis of cell lines as models of primary tumors across 22 tumor types
    “...Cell lines are used ubiquitously in cancer research but how well they represent the tumor type...”
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  4. 15824
    N-glycosylation-defective splice variants of neuropilin-1 promote metastasis by activating endosomal signals
    “...O-glycosylation of neuropilin-1 is involved in cancer migration and invasion. Here, the authors...”
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  5. 15825
    Pregnancy reprograms the epigenome of mammary epithelial cells and blocks the development of premalignant lesions
    “... the pre-disposition to cancer. Here, the authors examine the epigenetic landscape of mammary epithelial...”
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  6. 15826
    The essential role of PRAK in tumor metastasis and its therapeutic potential
    “...Metastasis is one of the leading causes of cancer-related death. Here, the authors report a pro...”
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  7. 15827
    Unraveling a tumor type-specific regulatory core underlying E2F1-mediated epithelial-mesenchymal transition to predict receptor protein signatures
    “...Deregulation of E2F family transcription factors is associated with cancer progression...”
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  8. 15828
    Coagulation induced by C3aR-dependent NETosis drives protumorigenic neutrophils during small intestinal tumorigenesis
    “...It is unclear whether cancer-related hypercoagulation and neutrophilia contribute to tumorigenesis...”
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  9. 15829
    Reversal of pancreatic desmoplasia by re-educating stellate cells with a tumour microenvironment-activated nanosystem
    “...Stromal-tumour interactions play an important role in pancreatic cancer progression. Here...”
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  10. 15830
    Canine tumor mutational burden is correlated with TP53 mutation across tumor types and breeds
    “...Genomic studies of canine tumours have been done for individual cancer types or dog breeds. Here...”
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  11. 15831
    Biomaterial-based scaffold for in situ chemo-immunotherapy to treat poorly immunogenic tumors
    “...The immunosuppressive tumour microenvironment impairs immunotherapy in poorly immunogenic cancer...”
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  12. 15832
    LncSox4 promotes the self-renewal of liver tumour-initiating cells through Stat3-mediated Sox4 expression
    “...Liver tumour-initiating cells (TICs) may be responsible for liver cancer initiation and recurrence...”
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  13. 15833
    Subtype-specific secretomic characterization of pulmonary neuroendocrine tumor cells
    “...Secreted proteins present a rich resource of potential cancer biomarkers. Here, the authors use...”
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  14. 15834
    Parkin targets HIF-1α for ubiquitination and degradation to inhibit breast tumor progression
    “... to cancer suppression but the mechanisms are unclear. Here the authors show that Parkin regulates HIF-1α...”
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  15. 15835
    Identification of the S100 fused-type protein hornerin as a regulator of tumor vascularity
    “... of pancreatic cancer endothelium via phage display and identify hornerin as a critical protein whose expression...”
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  16. 15836
    The transcription factor STAT5 catalyzes Mannich ligation reactions yielding inhibitors of leukemic cell proliferation
    “...The oncogene STAT5 is involved in cancer cell proliferation. Here, the authors use STAT5 protein...”
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  17. 15837
    Common DNA methylation dynamics in endometriod adenocarcinoma and glioblastoma suggest universal epigenomic alterations in tumorigenesis
    “...Jennifer Karlow et al. characterize the DNA methylation changes in two unrelated cancer types...”
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  18. 15838
    Modeling the effects of EMT-immune dynamics on carcinoma disease progression
    “... interactions and their impact on epithelial cancer progression, which highlights a controllable region...”
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  19. 15839
    Pharmacologic inhibition of protein phosphatase-2A achieves durable immune-mediated antitumor activity when combined with PD-1 blockade
    “...Protein phosphatase 2A (PP2A) has been proposed as a target for cancer immunotherapy. Here...”
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  20. 15840
    STING-dependent paracriny shapes apoptotic priming of breast tumors in response to anti-mitotic treatment
    “...Antimitotic compounds, such as paclitaxel, induce cell death in cycling cancer cells only. Here...”
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