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  1. 18001
    Single-cell barcode analysis provides a rapid readout of cellular signaling pathways in clinical specimens
    “... oligonucleotide-fluorophore conjugates, enabling multiplexed analysis of cancer pathways....”
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  2. 18002
    SWI/SNF catalytic subunits’ switch drives resistance to EZH2 inhibitors in ARID1A-mutated cells
    “...The mechanism of resistance to EZH2 inhibitors in cancers with inactivating SWI/SNF mutations...”
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  3. 18003
    Solution structures of multiple G-quadruplex complexes induced by a platinum(II)-based tripod reveal dynamic binding
    “...DNA G-quadruplexes occur in oncologically relevant regions, thus are interesting targets for cancer...”
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  4. 18004
    Imaging tumour cell heterogeneity following cell transplantation into optically clear immune-deficient zebrafish
    “... imaging to track and to assess functional diversity of individual cancer cells in vivo....”
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  5. 18005
    CD36 inhibits β-catenin/c-myc-mediated glycolysis through ubiquitination of GPC4 to repress colorectal tumorigenesis
    “... depending on tumour type. Here, the authors address CD36 function in colorectal cancer and show it acts as a...”
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  6. 18006
    Interdependent IL-7 and IFN-γ signalling in T-cell controls tumour eradication by combined α-CTLA-4+α-PD-1 therapy
    “... trials. Here, the authors report that mechanistically in bladder cancer such effect depends upon...”
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  7. 18007
    UTX is an escape from X-inactivation tumor-suppressor in B cell lymphoma
    “... to the cancer gender bias. Here the authors, using a mouse model of B cell lymphoma, show that UTX is a dosage...”
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  8. 18008
    BRCA1-associated structural variations are a consequence of polymerase theta-mediated end-joining
    “...Cancer mutational signatures have been associated with defects in genome maintenance pathways. Here...”
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  9. 18009
    Predicting treatment response from longitudinal images using multi-task deep learning
    “... and response prediction from longitudinal images in a multi-center study on rectal cancer....”
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  10. 18010
    Synthetic molecular recognition nanosensor paint for microalbuminuria
    “...Microalbuminuria, a clinical marker associated with cancer and hypertension, defined by low albumin...”
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  11. 18011
    A bidentate Polycomb Repressive-Deubiquitinase complex is required for efficient activity on nucleosomes
    “... PR-DUB complex, providing new insight into its regulation and how cancer-associated mutations disrupt...”
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  12. 18012
    Chronic expression of p16INK4a in the epidermis induces Wnt-mediated hyperplasia and promotes tumor initiation
    “... to develop cancer. Here, the authors show that chronic p16 expression in the mouse epidermis causes...”
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  13. 18013
    AGO-bound mature miRNAs are oligouridylated by TUTs and subsequently degraded by DIS3L2
    “...-microRNAs in AGO PAZ mutant expressing- or cancer cells....”
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  14. 18014
    Quantification of ongoing APOBEC3A activity in tumor cells by monitoring RNA editing at hotspots
    “...The DNA cytosine deaminases APOBEC3A and APOBEC3B have emerged from cancer genomics studies...”
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  15. 18015
    Proteome activity landscapes of tumor cell lines determine drug responses
    “...Proteome activity has a major role in cancer progression and response to drugs. Here, the authors...”
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  16. 18016
    3D tumor spheroid microarray for high-throughput, high-content natural killer cell-mediated cytotoxicity
    “... combination therapies against established cancer cell lines, focusing especially on NK cell-mediated...”
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  17. 18017
    Artificially engineered antiferromagnetic nanoprobes for ultra-sensitive histopathological level magnetic resonance imaging
    “... cancer metastasis. Here, the authors develop an ultra-sensitive antiferromagnetic nanoparticle probe...”
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  18. 18018
    Intragenic recruitment of NF-κB drives splicing modifications upon activation by the oncogene Tax of HTLV-1
    “..., and cancer. Here, the authors show that the NF-κB factor RELA regulates splicing of target genes...”
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  19. 18019
    Diagnosis of fusion genes using targeted RNA sequencing
    “...Rapid and accurate detection of fusion genes is important in cancer diagnostics. Here, the authors...”
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  20. 18020
    BRE/BRCC45 regulates CDC25A stability by recruiting USP7 in response to DNA damage
    “...Loss of BRCA2 leads to cancer formation. Here, the authors use an insertional mutagenesis approach...”
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