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  1. 18141
    The leukemic oncogene EVI1 hijacks a MYC super-enhancer by CTCF-facilitated loops
    “...Chromosome rearrangements can be a cause of altered oncogene expression in cancer, such as a 3q26...”
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  2. 18142
    Chronic stress in mice remodels lymph vasculature to promote tumour cell dissemination
    “...Adverse life events have been associated with reduced survival in cancer patients. Here...”
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  3. 18143
    Lineage-specific roles of the cytoplasmic polyadenylation factor CPEB4 in the regulation of melanoma drivers
    “...Cytoplasmic polyadenylated transcripts have been poorly characterized, particularly in cancer. Here...”
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  4. 18144
    miR-625-3p regulates oxaliplatin resistance by targeting MAP2K6-p38 signalling in human colorectal adenocarcinoma cells
    “...Oxaliplatin resistance in colorectal cancers is a major clinical problem, and predictive markers...”
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  5. 18145
    Multiple low dose therapy as an effective strategy to treat EGFR inhibitor-resistant NSCLC tumours
    “...A drug used at the maximum tolerated dose can exert a strong selective pressure on cancer cells...”
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  6. 18146
    The lysophospholipase D enzyme Gdpd3 is required to maintain chronic myelogenous leukaemia stem cells
    “...How lipid metabolism can affect cancer recurrence is still unclear. Here, the authors show...”
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  7. 18147
    Control of diabetic hyperglycaemia and insulin resistance through TSC22D4
    “... of cancer cachexia. Here, the authors show TSC22D4 inhibition improves insulin sensitivity in several mouse...”
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  8. 18148
    Sialyl Lewisx-P-selectin cascade mediates tumor–mesothelial adhesion in ascitic fluid shear flow
    “... metastasis. Here, the authors show that metastatic cancer stem cells tether more and roll slower than the non...”
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  9. 18149
    LINC complex-Lis1 interplay controls MT1-MMP matrix digest-on-demand response for confined tumor cell migration
    “...The ability of cancer cells to migrate through small, constricted areas is limited by nuclear...”
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  10. 18150
    MYC functions as a switch for natural killer cell-mediated immune surveillance of lymphoid malignancies
    “...Oncogene addiction is considered as a cancer cell-autonomous phenomenon, but can also influence...”
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  11. 18151
    Bioengineered bacteria-derived outer membrane vesicles as a versatile antigen display platform for tumor vaccination via Plug-and-Display technology
    “...-tumor immune responses in preclinical cancer models....”
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  12. 18152
    A masked initiation region in retinoblastoma protein regulates its proteasomal degradation
    “... ubiquitination in cervical cancer cells, however proteasomal degradation requires cleavage of Rb after Lys 810...”
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  13. 18153
    Interplay between hypoxia and androgen controls a metabolic switch conferring resistance to androgen/AR-targeted therapy
    “...Prostate cancer often develops resistance to androgen receptor (AR) targeting drugs. Here...”
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  14. 18154
    Reprogramming the immunological microenvironment through radiation and targeting Axl
    “... to radiation in breast cancer cells can be due to Axl expression that suppresses antigen presentation though...”
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  15. 18155
    Effective combinatorial immunotherapy for penile squamous cell carcinoma
    “...Penile squamous cell carcinoma (PSCC) is a cancer that is associated with significant mortality...”
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  16. 18156
    Callyspongiolide kills cells by inducing mitochondrial dysfunction via cellular iron depletion
    por Jaeyoung Ha, Seung Bum Park
    Publicado 2021
    “... lung cancer cells, Ha and Park employed TS-FITGE technique, a label-free target identification method...”
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  17. 18157
    Therapeutic modulation of phagocytosis in glioblastoma can activate both innate and adaptive antitumour immunity
    “...Professional antigen presenting cells (APCs) are deterred from phagocytosing cancer cells...”
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  18. 18158
    Ap4 is rate limiting for intestinal tumor formation by controlling the homeostasis of intestinal stem cells
    “.... Here, the authors show in a mouse model of inherited colorectal cancer that deletion of AP4 decreased...”
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  19. 18159
    Human breast tumor-infiltrating CD8+ T cells retain polyfunctionality despite PD-1 expression
    “... of T cells exhaustion. Here the authors show that CD8T cells isolated from breast cancer patients...”
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  20. 18160
    c-Src phosphorylation and activation of hexokinase promotes tumorigenesis and metastasis
    “..., the authors show that c-Src induces the metabolic reprogramming of cancer cells by phosphorylating hexokinases...”
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