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  1. 18181
    Super-resolution imaging reveals the evolution of higher-order chromatin folding in early carcinogenesis
    “...Aberrant chromatin structure is often found in cancer. Here, the authors optimise super-resolution...”
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  2. 18182
    Critical role of the HDAC6–cortactin axis in human megakaryocyte maturation leading to a proplatelet-formation defect
    “...Histone deacetylase (HDAC) inhibitors, a class of cancer therapeutics, cause thrombocytopenia via...”
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  3. 18183
    Molecularly targeted photothermal ablation improves tumor specificity and immune modulation in a rat model of hepatocellular carcinoma
    “...-relevant rat model of liver cancer. They further show that MTPA modulates the intratumoral immune profile...”
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  4. 18184
    mTORC1 couples cyst(e)ine availability with GPX4 protein synthesis and ferroptosis regulation
    “... and show that cancer cells are sensitized to ferroptosis by mTORC1 inhibition....”
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  5. 18185
    Wnt1 silences chemokine genes in dendritic cells and induces adaptive immune resistance in lung adenocarcinoma
    “... both on the cancer and immune cells....”
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  6. 18186
    Inference of transcription factor binding from cell-free DNA enables tumor subtype prediction and early detection
    “...Deregulation of transcription factors is frequently observed in cancer. Here, the authors develop a...”
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  7. 18187
    A region-resolved mucosa proteome of the human stomach
    “... as well as mucosa proteomes of tumor and tumor nearby tissue from gastric cancer patients....”
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  8. 18188
    Anti-LRP5/6 VHHs promote differentiation of Wnt-hypersensitive intestinal stem cells
    “...Enhanced Wnt receptor activity is a major cause of cancer development. Here the authors identify...”
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  9. 18189
    Intratumoral IL-12 delivery empowers CAR-T cell immunotherapy in a pre-clinical model of glioblastoma
    “...Glioblastoma multiform (GBM) is a common and aggressive type of primary brain cancer that currently...”
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  10. 18190
    AIM1 is an actin-binding protein that suppresses cell migration and micrometastatic dissemination
    “... and cell migration in prostate epithelial cells, acting as a metastatic suppressor in cancer cells....”
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  11. 18191
    Discovery of a dual Ras and ARF6 inhibitor from a GPCR endocytosis screen
    “...While Ras is a promising target for cancer therapy, development of inhibitors targeting Ras...”
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  12. 18192
    A user guide for the online exploration and visualization of PCAWG data
    “...The Pan-Cancer Analysis of Whole Genomes project generated a vast array of data. In this article...”
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  13. 18193
    Rational design of a triple-type human papillomavirus vaccine by compromising viral-type specificity
    “...More than 18 human papillomaviruses (HPV) are associated with cervical cancer, and ideally vaccines...”
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  14. 18194
    Two parallel pathways connect glutamine metabolism and mTORC1 activity to regulate glutamoptosis
    “... have two regulatory connections with relevance to cancer therapeutics design....”
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  15. 18195
    Glycogen synthase kinase 3 controls migration of the neural crest lineage in mouse and Xenopus
    “...Defects in neural crest development cause neurocristopathies and cancer, but what regulates...”
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  16. 18196
    Tumour-on-chip microfluidic platform for assessment of drug pharmacokinetics and treatment response
    “... microfluidics to study drug effects at physiological exposures preclinically. They test colorectal cancer...”
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  17. 18197
    Serine-linked PARP1 auto-modification controls PARP inhibitor response
    “... to cancer cells. Here the authors identify three serine residues within PARP1 as key sites whose efficient...”
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  18. 18198
    Advances in diagnostic interventional pulmonology
    por Nassar Al-Zubaidi, Ayman O Soubani
    Publicado 2015
    “... in diagnosis and staging of lung cancer without the need for more invasive procedures. This report describes...”
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  19. 18199
    Tumor-derived NKG2D ligand sMIC reprograms NK cells to an inflammatory phenotype through CBM signalosome activation
    “... in order to enhance current NK cell-based cancer immunotherapies....”
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  20. 18200
    Specific stereochemistry of OP-1074 disrupts estrogen receptor alpha helix 12 and confers pure antiestrogenic activity
    “...Estrogen receptor alpha (ERα) plays critical roles in the etiology and treatment of breast cancer...”
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