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221por Kadi Lõhmussaar, Oded Kopper, Jeroen Korving, Harry Begthel, Celien P. H. Vreuls, Johan H. van Es, Hans Clevers“... murine oviductal and OSE tissues that allow cancer modeling via CRISPR-Cas9 genome editing, and report a...”
Publicado 2020
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222por Lazaros Lataniotis, Andreas Albrecht, Fatma O. Kok, Clinton A. L. Monfries, Lorena Benedetti, Nathan D. Lawson, Simon M. Hughes, Kathleen Steinhofel, Manuel Mayr, Anna Zampetaki“... the use of CRISPR/Cas9 as a powerful tool to delineate the function and regulation of miRNA families...”
Publicado 2017
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223por Carlos G. Sanchez, Christopher M. Acker, Audrey Gray, Malini Varadarajan, Cheng Song, Nadire R. Cochran, Steven Paula, Alicia Lindeman, Shaojian An, Gregory McAllister, John Alford, John Reece-Hoyes, Carsten Russ, Lucas Craig, Ketthsy Capre, Christian Doherty, Gregory R. Hoffman, Sarah J. Luchansky, Manuela Polydoro, Ricardo Dolmetsch, Fiona Elwood“...Using an unbiased genome-wide CRISPR screen approach, Sanchez et al. identified modulators...”
Publicado 2021
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224por Bo Li, Sara M. Clohisey, Bing Shao Chia, Bo Wang, Ang Cui, Thomas Eisenhaure, Lawrence D. Schweitzer, Paul Hoover, Nicholas J. Parkinson, Aharon Nachshon, Nikki Smith, Tim Regan, David Farr, Michael U. Gutmann, Syed Irfan Bukhari, Andrew Law, Maya Sangesland, Irit Gat-Viks, Paul Digard, Shobha Vasudevan, Daniel Lingwood, David H. Dockrell, John G. Doench, J. Kenneth Baillie, Nir Hacohen“...Here, Li et al. perform a genome-wide CRISPR screen to identify host dependency factors...”
Publicado 2020
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225Structure and mechanism of a Type III CRISPR defence DNA nuclease activated by cyclic oligoadenylatepor Stephen A. McMahon, Wenlong Zhu, Shirley Graham, Robert Rambo, Malcolm F. White, Tracey M. Gloster“...Antiviral defence type III CRISPR systems produce cyclic oligoadenylates (cOA) as second messengers...”
Publicado 2020
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226por Benjamin C. Buchmuller, Konrad Herbst, Matthias Meurer, Daniel Kirrmaier, Ehud Sass, Emmanuel D. Levy, Michael Knop“... of the chosen strain. Here the authors present CASTLING which uses CRISPR-Cas12a and oligonucleotide pools...”
Publicado 2019
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227por Miguel A. Moreno-Mateos, Juan P. Fernandez, Romain Rouet, Charles E. Vejnar, Maura A. Lane, Emily Mis, Mustafa K. Khokha, Jennifer A. Doudna, Antonio J. Giraldez“...Cpf1 is a promising addition to the CRISPR toolkit but displays wide variability of activity...”
Publicado 2017
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228“... with targetedin vitroCRISPR-Cas9 fragmentation to enable massively parallel analysis in the thousands....”
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229por Peiwu Qin, Mahmut Parlak, Cem Kuscu, Jigar Bandaria, Mustafa Mir, Karol Szlachta, Ritambhara Singh, Xavier Darzacq, Ahmet Yildiz, Mazhar Adli“...CRISPR-Cas9 has been used to image repetitive loci in live cells to explore genome organization...”
Publicado 2017
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230por Rafael Pinilla-Redondo, Saadlee Shehreen, Nicole D. Marino, Robert D. Fagerlund, Chris M. Brown, Søren J. Sørensen, Peter C. Fineran, Joseph Bondy-Denomy“...Mobile genetic elements have evolved anti-CRISPR (Acr) proteins to bypass the immunity provided...”
Publicado 2020
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231por Xi Xiang, Giulia I. Corsi, Christian Anthon, Kunli Qu, Xiaoguang Pan, Xue Liang, Peng Han, Zhanying Dong, Lijun Liu, Jiayan Zhong, Tao Ma, Jinbao Wang, Xiuqing Zhang, Hui Jiang, Fengping Xu, Xin Liu, Xun Xu, Jian Wang, Huanming Yang, Lars Bolund, George M. Church, Lin Lin, Jan Gorodkin, Yonglun LuoEnlace del recurso
Publicado 2021
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232por Joanna Young, Caia Dominicus, Jeanette Wagener, Simon Butterworth, Xingda Ye, Gavin Kelly, Merav Ordan, Becky Saunders, Rachael Instrell, Michael Howell, Aengus Stewart, Moritz Treeck“...Targeted CRISPR libraries expand the use of genetic screens across experimental conditions. Here...”
Publicado 2019
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233por Francis P. Pankowicz, Mercedes Barzi, Xavier Legras, Leroy Hubert, Tian Mi, Julie A. Tomolonis, Milan Ravishankar, Qin Sun, Diane Yang, Malgorzata Borowiak, Pavel Sumazin, Sarah H. Elsea, Beatrice Bissig-Choisat, Karl-Dimiter Bissig“... of toxic metabolites in the liver. Here the authors use CRISPR/Cas9 to 'cure' the disease in mice...”
Publicado 2016
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234
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235“...Abstract CRISPR/Cas9-mediated genome editing is an important and versatile technology in modern...”
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236por Krzysztof Chylinski, Maria Hubmann, Ruth E. Hanna, Connor Yanchus, Georg Michlits, Esther C. H. Uijttewaal, John Doench, Daniel Schramek, Ulrich Elling“... develop CRISPR-Switch, a Cre recombinase ON/OFF-controlled sgRNA cassette that allows consecutive editing...”
Publicado 2019
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237por Yuning Song, Yuxin Xu, Jichao Deng, Mao Chen, Yi Lu, Yong Wang, Haobin Yao, Lina Zhou, Zhiquan Liu, Liangxue Lai, Zhanjun Li“... are known to cause recessive albinism in humans and other species. In this study, to test whether the CRISPR...”
Publicado 2017
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238por Victor Aprilyanto, Redi Aditama, Zulfikar Achmad Tanjung, Condro Utomo, Tony Liwang“..., is a major problem which limits the applications of CRISPR/Cas9 genome editing system. CRISPR Off...”
Publicado 2021
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239
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240por Duverney Chaverra-Rodriguez, Vanessa M. Macias, Grant L. Hughes, Sujit Pujhari, Yasutsugu Suzuki, David R. Peterson, Donghun Kim, Sage McKeand, Jason L. RasgonEnlace del recurso
Publicado 2018
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