Mostrando 441 - 460 Resultados de 1,137 Para Buscar '"CRISPR"', tiempo de consulta: 0.06s Limitar resultados
  1. 441
    Enhanced CRISPR-based DNA demethylation by Casilio-ME-mediated RNA-guided coupling of methylcytosine oxidation and DNA repair pathways
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  2. 442
    Mutations introduced in susceptibility genes through CRISPR/Cas9 genome editing confer increased late blight resistance in potatoes
    “... in potatoes, including two DMR6 potato homologues. Using a CRISPR/Cas9 system, which conferred co-expression...”
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  3. 443
    Multiplexed CRISPR-Cas9 system in a single adeno-associated virus to simultaneously knock out redundant clock genes
    “... multiple clock genes in a streamlined and efficient manner, we developed a CRISPR-Cas9-based single adeno...”
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  4. 444
    Sensitive detection of a bacterial pathogen using allosteric probe-initiated catalysis and CRISPR-Cas13a amplification reaction
    “.... present a detection system, involving a combination of nucleic acid-based allosteric probes and CRISPR-Cas...”
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  5. 445
    Structure of Csx1-cOA4 complex reveals the basis of RNA decay in Type III-B CRISPR-Cas
    “...Type III CRISPR-Cas RNases from the Csm and Csx families are activated by cyclic oligoadenylates...”
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  6. 446
    First Year Course-Based Undergraduate Research Experience (CURE) Using the CRISPR/Cas9 Genome Engineering Technology in Zebrafish
    por Jay M. Bhatt, Anil Kumar Challa
    Publicado 2018
    “... the CRISPR-Cas9 gene editing system to disrupt specific genes in the zebrafish. The course was offered...”
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  7. 447
    A Novel Isogenic Human Cell-Based System for MEN1 Syndrome Generated by CRISPR/Cas9 Genome Editing
    Materias: “...CRISPR/Cas9 genome editing...”
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  8. 448
    A Genome-Wide CRISPR/Cas9 Screen Reveals that Riboflavin Regulates Hydrogen Peroxide Entry into HAP1 Cells
    “...-induced cytotoxicity is an iron-dependent process in HAP1 cells and conducted a CRISPR/Cas9-based survival...”
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  9. 449
    Function of the CRISPR-Cas System of the Human Pathogen <named-content content-type="genus-species">Clostridium difficile</named-content>
    “... in bacteriophage-rich gut communities. CRISPR (clustered regularly interspaced short palindromic repeats)-Cas...”
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  10. 450
    CRISPR-Cas9-Mediated Genome Editing in <named-content content-type="genus-species">Leishmania donovani</named-content>
    por Wen-Wei Zhang, Greg Matlashewski
    Publicado 2015
    “...ABSTRACT The prokaryotic CRISPR (clustered regularly interspaced short palindromic repeat)-Cas9...”
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  11. 451
    Muscle-specific CRISPR/Cas9 dystrophin gene editing ameliorates pathophysiology in a mouse model for Duchenne muscular dystrophy
    “...CRISPR/Cas9-mediated gene editing is an emerging strategy to treat Duchenne muscular dystrophy...”
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  12. 452
    High-throughput screen reveals sRNAs regulating crRNA biogenesis by targeting CRISPR leader to repress Rho termination
    “.... Here the authors identify PhrS sRNA in Pseudomonas as a positive regulator of CRISPR, and show PhrS...”
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  13. 453
    Genome-wide CRISPR/Cas9 screening in human iPS derived cardiomyocytes uncovers novel mediators of doxorubicin cardiotoxicity
    “.... Application of CRISPR/Cas9-based approaches for genome-scale functional screening in iPS-derived cells...”
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  14. 454
    Type I-F CRISPR-Cas resistance against virulent phages results in abortive infection and provides population-level immunity
    “...Bacteria use CRISPR-Cas systems to protect themselves against viral infections. Here, Watson et al...”
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  15. 455
    CRISPR/Cas9-mediated PD-1 disruption enhances anti-tumor efficacy of human chimeric antigen receptor T cells
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  16. 456
    Optimized CRISPR/Cas9-mediated in vivo genome engineering applicable to monitoring dynamics of endogenous proteins in the mouse neural tissues
    por Takahiko Matsuda, Izumi Oinuma
    Publicado 2019
    “... and engineering of the endogenous proteins of interest. By combining the CRISPR/Cas9 genome editing technology...”
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  17. 457
    A CRISPR/Cas9 guidance RNA screen platform for HIV provirus disruption and HIV/AIDS gene therapy in astrocytes
    por Zaohua Huang, Madahavan Nair
    Publicado 2017
    “... the multiple HIV reservoirs in the human body, including astrocytes in the human brain. CRISPR/Cas9 system...”
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  18. 458
    In vivo genome-wide CRISPR screen reveals breast cancer vulnerabilities and synergistic mTOR/Hippo targeted combination therapy
    “... CRISPR screen in TNBCs, the authors identify tumorigenic functions for components of the mTORC1/2 complex...”
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  19. 459
    Generation of a DKK2 homozygous knockout human embryonic stem cell line using the CRISPR/Cas9 system
    “... embryonic stem cell (hESC) line through the CRISPR/Cas9 genome-editing technology. This cell line, which...”
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  20. 460
    CRISPR/Cas9 generated knockout mice lacking phenylalanine hydroxylase protein as a novel preclinical model for human phenylketonuria
    “...) (Hom) mouse model, which was developed in the C57BL/6 J strain using CRISPR/Cas9 where codon 7 (GAG...”
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