Mostrando 681 - 700 Resultados de 1,137 Para Buscar '"CRISPR"', tiempo de consulta: 0.06s Limitar resultados
  1. 681
    Overcoming evolved resistance to population-suppressing homing-based gene drives
    “...Abstract The recent development of a CRISPR-Cas9-based homing system for the suppression...”
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  2. 682
    Prophage-Mediated Disruption of Genetic Competence in <named-content content-type="genus-species">Staphylococcus pseudintermedius</named-content>
    “...), and CRISPR/Cas systems differs significantly among MRSP clones. The isolates with GyrA+GrlA mutations...”
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  3. 683
    Efficient biallelic knock-in in mouse embryonic stem cells by in vivo-linearization of donor and transient inhibition of DNA polymerase θ/DNA-PK
    por Daisuke Arai, Yoichi Nakao
    Publicado 2021
    “...Abstract CRISPR/Cas9-mediated homology-directed repair (HDR) is used for error-free targeted knock...”
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  4. 684
    Targeting of SET/I2PP2A oncoprotein inhibits Gli1 transcription revealing a new modulator of Hedgehog signaling
    “... and localized in the ciliated organs. In the present work, we show that CRISPR/Cas9-mediated knockdown of setb...”
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  5. 685
    Efficient genome editing of an extreme thermophile, Thermus thermophilus, using a thermostable Cas9 variant
    “... substrates are often thermolabile. We sought to develop a thermostable CRISPR-Cas9 based system for genome...”
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  6. 686
    Evaluation of mutation rates, mosaicism and off target mutations when injecting Cas9 mRNA or protein for genome editing of bovine embryos
    “...Abstract The CRISPR/Cas9 genome editing tool has the potential to improve the livestock breeding...”
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  7. 687
    Characterization of HA-tagged α9 and α10 nAChRs in the mouse cochlea
    “... of these proteins have been hampered by the absence of reliable antibodies. To overcome this obstacle, CRISPR-Cas9...”
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  8. 688
    ssAAVs containing cassettes encoding SaCas9 and guides targeting hepatitis B virus inactivate replication of the virus in cultured cells
    “... on CRISPR/Cas9, provide the means for permanently disabling cccDNA. However, efficient delivery of antiviral...”
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  9. 689
    Diversity of Acinetobacter baumannii in four French military hospitals, as assessed by multiple locus variable number of tandem repeats analysis.
    “... clones which members were found in the different hospitals. Analysis of two CRISPR-cas systems helped...”
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  10. 690
    The susceptibility of Pseudomonas aeruginosa strains from cystic fibrosis patients to bacteriophages.
    “... CRISPR-Cas system (Clustered Regularly Interspaced Short Palindromic Repeats and Crisper associated genes...”
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  11. 691
    Split drive killer-rescue provides a novel threshold-dependent gene drive
    “... be engineered using a combination of toxin-antidote and CRISPR components, each of which are already being...”
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  12. 692
    Targeted insertion of an anti-CD2 monoclonal antibody transgene into the GGTA1 locus in pigs using FokI-dCas9
    “... of donated human organs and tissues. CRISPR/Cas9 has facilitated the silencing of genes in donor pigs...”
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  13. 693
    Midnolin is a novel regulator of parkin expression and is associated with Parkinson’s Disease
    “... cells created using CRISPR/Cas9 technology displayed significantly impaired neurite outgrowth...”
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  14. 694
    Thymosin beta-4 regulates activation of hepatic stellate cells via hedgehog signaling
    “... by the decreased expression of both smoothened and GLI2. A TB4 CRISPR also blocked the activation of primary HSCs...”
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  15. 695
    Inhibition of androgen receptor promotes CXC-chemokine receptor 7-mediated prostate cancer cell survival
    “... (CRISPR) directed Cas9 nuclease-mediated gene editing of CXCR7 revealed that prostate cancer cells depend...”
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  16. 696
    An epigenetic GPI anchor defect impairs TLR4 signaling in the B cell transdifferentiation model for primary human monocytes BLaER1
    “... cells are commonly used for loss-of-function studies, such as with CRISPR-Cas9 editing. A recently...”
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  17. 697
    Gene therapy in PIDs, hemoglobin, ocular, neurodegenerative, and hemophilia B disorders
    “..., as proven in preclinical studies. Recently, the clustered regularly interspaced palindromic repeats (CRISPR...”
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  18. 698
    Improved bacterial leaf blight disease resistance in the major elite Vietnamese rice cultivar TBR225 via editing of the OsSWEET14 promoter.
    “..., PthXo3 or TalF TALEs DNA target sequences of the OsSWEET14 promoter were obtained using the CRISPR/Cas9...”
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  19. 699
    An autoimmune disease risk variant: A trans master regulatory effect mediated by IRF1 under immune stimulation?
    “... and causes widespread transcriptional effects. Genome editing by CRISPR had suggestive recapitulation...”
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  20. 700
    Different Roles of Mitochondrial Calcium Uniporter Complex Subunits in Growth and Infectivity of <italic toggle="yes">Trypanosoma cruzi</italic>
    “... (CRISPR)/Cas9 led to a marked decrease in mitochondrial Ca2+ uptake without affecting the membrane...”
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