Mostrando 721 - 740 Resultados de 1,137 Para Buscar '"CRISPR"', tiempo de consulta: 0.12s Limitar resultados
  1. 721
    S100A8 expression in oviduct mucosal epithelial cells is regulated by estrogen and affects mucosal immune homeostasis
    “... the clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 method...”
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  2. 722
    Transposable elements that have recently been mobile in the human genome
    “... correlations between germline and somatic TE mobility. Using CRISPR/Cas9 deletion, we show that an RMS-derived...”
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  3. 723
    Decoupling tRNA promoter and processing activities enables specific Pol-II Cas9 guide RNA expression
    “...The utility of CRISPR-based technologies could be enhanced with the ability to control the spatial...”
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  4. 724
    Gene essentiality landscape and druggable oncogenic dependencies in herpesviral primary effusion lymphoma
    “...) is lacking. Here the authors performed in vitro CRISPR/Cas9 knock-out screens to identify 210 PEL-specific...”
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  5. 725
    Conditional control of RNA-guided nucleic acid cleavage and gene editing
    “...Constituitively active CRISPR systems have the risk of adverse off-target effects. Here the authors...”
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  6. 726
    LncRNA AK023948 is a positive regulator of AKT
    “... setup a gain of function CRISPR-based screen and identify a lncRNA that positively regulates AKT...”
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  7. 727
    Targeted recombination between homologous chromosomes for precise breeding in tomato
    “... of crop plants. Here, Filler Hayutet al. show that CRISPR-Cas9 can be used to induce DNA double strand...”
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  8. 728
    A CRISPRi screen in E. coli reveals sequence-specific toxicity of dCas9
    “...CRISPR interference (CRISPRi) is a method for targeted silencing of transcription that requires...”
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  9. 729
    A Cas9 with PAM recognition for adenine dinucleotides
    “...Protospacer adjacent motif (PAM) requirements limit the target range of CRISPR endonucleases. Here...”
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  10. 730
    Small molecule regulated sgRNAs enable control of genome editing in E. coli by Cas9
    “...Bacteria lack the same suite of CRISPR tools that have been developed for mammalian cells. Here...”
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  11. 731
    Trithorax dependent changes in chromatin landscape at enhancer and promoter regions drive female puberty
    “... of the arcuate nucleus. Here, by CRISPR-Cas9-directed epigenome editing and RNAi, the authors show...”
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  12. 732
    Genome editing in butterflies reveals that spalt promotes and Distal-less represses eyespot colour patterns
    por Linlin Zhang, Robert D. Reed
    Publicado 2016
    “... eyespots. Here, Zhang and Reed use CRISPR/Cas9 genome editing to show that while spalt is a positive...”
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  13. 733
    Engineered reproductively isolated species drive reversible population replacement
    “... the authors use CRISPR to engineer multiple barriers in D. melanogaster and model their spread....”
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  14. 734
    Trio deep-sequencing does not reveal unexpected off-target and on-target mutations in Cas9-edited rhesus monkeys
    “...The off-target effects and on-target mutations of CRISPR editing in higher non-human primates...”
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  15. 735
    Transforming insect population control with precision guided sterile males with demonstration in flies
    “... CRISPR-based technology and SIT to develop a precision guided SIT (pgSIT), and demonstrate its proof...”
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  16. 736
    Efficient generation of mouse models of human diseases via ABE- and BE-mediated base editing
    “...CRISPR-based base editors allow for single nucleotide genome editing in a range of organisms. Here...”
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  17. 737
    Genome editing abrogates angiogenesis in vivo
    “...Abnormal angiogenesis causes many ocular diseases. Here the authors employ CRISPR/Cas9 gene editing...”
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  18. 738
    Ex vivo editing of human hematopoietic stem cells for erythroid expression of therapeutic proteins
    “... safe and highly transcribed locus. Here the authors ex vivo edit HPSCs using CRISPR-Cas9 to integrate...”
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  19. 739
    Synthetic chimeric nucleases function for efficient genome editing
    “...CRISPR-Cas systems have well characterized, modular structures. Here the authors use...”
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  20. 740
    CopyCatchers are versatile active genetic elements that detect and quantify inter-homolog somatic gene conversion
    “...CRISPR-based genetic elements can copy themselves across host genomes. Here the authors introduce...”
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