Mostrando 861 - 880 Resultados de 1,137 Para Buscar '"CRISPR"', tiempo de consulta: 0.07s Limitar resultados
  1. 861
    The broad role of Nkx3.2 in the development of the zebrafish axial skeleton.
    “... is not fully described. We generated a mutant allele of nkx3.2 in zebrafish with CRISPR/Cas9 and applied a...”
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  2. 862
    Phosphorylation of PUF-A/PUM3 on Y259 modulates PUF-A stability and cell proliferation.
    “... was knocked out by the Crispr/Cas9 method in human cervix epithelial HeLa cells. Loss of PUF-A in HeLa cells...”
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  3. 863
    Genetic dependency of Alzheimer’s disease-associated genes across cells and tissue types
    “... as therapeutic strategies, the consequence of such alterations remain largely unknown. Herein, we analyzed CRISPR...”
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  4. 864
    Knockout of zebrafish desmin genes does not cause skeletal muscle degeneration but alters calcium flux
    “...) mutant lines carrying loss-of-function mutations for each gene by using CRISPR/Cas9. Mutants are viable...”
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  5. 865
    Efficient viral delivery of Cas9 into human safe harbor
    “...Abstract Gene editing using CRISPR/Cas9 is a promising method to cure many human genetic diseases...”
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  6. 866
    Functional divergence in the genus Oenococcus as predicted by genome sequencing of the newly-described species, Oenococcus kitaharae.
    “... and a CRISPR locus) which are lacking in O. oeni. The two genomes also appear to differentially encode...”
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  7. 867
    Generation of LUMCi041-A-2: Equipping a PAX3 reporter iPSC line with doxycycline inducible H2B-mTurquoise2 for live cell imaging
    “... into the AAVS1 locus of PAX3-Venus iPSCs via CRISPR/Cas9. H2B-mTurquoise2 expression is absent but readily...”
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  8. 868
    Functional Studies of Plant Latex as a Rich Source of Bioactive Compounds: Focus on Proteins and Alkaloids
    “... pharmacological activities using modern techniques such as CRISPR/Cas9 gene editing. Despite the centuries-old...”
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  9. 869
    rs1944919 on chromosome 11q23.1 and its effector genes COLCA1/COLCA2 confer susceptibility to primary biliary cholangitis
    “... the CRISPR/Cas9 system and differed between rs1944919-G/G clones and -T/T clones. To our knowledge...”
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  10. 870
    The Cannabinoid Receptor Interacting Proteins 1 of zebrafish are not required for morphological development, viability or fertility
    “... elsewhere. For example, cnrip1b is expressed in forming skeletal muscle. CRISPR/Cas9 genome editing...”
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  11. 871
    Multiple gene substitution by Target-AID base-editing technology in tomato
    “... technology with the CRISPR-Cas 9 system fused with activation-induced cytidine deaminase (AID) resulted...”
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  12. 872
    Simple and large-scale chromosomal engineering of mouse zygotes via in vitro and in vivo electroporation
    “...Abstract The clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 system has...”
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  13. 873
    Acid ceramidase controls apoptosis and increases autophagy in human melanoma cells treated with doxorubicin
    “... and apoptosis. Here we investigated the impact of AC ablation via CRISPR-Cas9 gene editing on the response of A...”
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  14. 874
    An integrated platform for genome engineering and gene expression perturbation in Plasmodium falciparum
    “... several key functional genetics outcomes via CRISPR/Cas9 and other methods from a common, validated...”
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  15. 875
    Sulfation of a FLAG tag mediated by SLC35B2 and TPST2 affects antibody recognition.
    “... recombinant proteins of interest. In this study, we performed a CRISPR-based genetic screening to identify...”
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  16. 876
    Targeted knockout of the gene OsHOL1 removes methyl iodide emissions from rice plants
    “... to further increases of iodine emissions. In this work, we used the genome editing CRISPR/Cas9 technology...”
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  17. 877
    Anti-inflammatory role of Gpnmb in adipose tissue of mice
    “... cells. We generated a Gpnmb-knockout mouse line using Crispr-Cas9 to assess the role of Gpnmb in a diet...”
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  18. 878
    Translational repression of NMD targets by GIGYF2 and EIF4E2.
    “...-wide CRISPR flow cytometry screen to identify regulators of mRNAs with premature termination codons...”
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  19. 879
    H3K27M induces defective chromatin spread of PRC2-mediated repressive H3K27me2/me3 and is essential for glioma tumorigenesis
    “... and isogenic CRISPR-edited controls and show that H3K27M induces defective chromatin spread of PRC2-mediated...”
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  20. 880
    Active nuclear transcriptome analysis reveals inflammasome-dependent mechanism for early neutrophil response to Mycobacterium marinum
    “... (wu: fb15h11) and il1β. Crispr/Cas9-mediated knockout of caspase b, which acts by proteolytic...”
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