Mostrando 981 - 1,000 Resultados de 1,137 Para Buscar '"CRISPR"', tiempo de consulta: 0.06s Limitar resultados
  1. 981
    Essential role of mitochondrial Stat3 in p38MAPK mediated apoptosis under oxidative stress
    “...2O2 or hypoxia using siRNA and CRISPR/Cas9 genome-editing. We found dysregulation of mitochondrial...”
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  2. 982
    IRE1α and IGF signaling predict resistance to an endoplasmic reticulum stress-inducing drug in glioblastoma cells
    “... identified two additional genes selectively overexpressed among non-responders, IGFBP3 and IGFBP5. CRISPR...”
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  3. 983
    Autophagy regulates the stemness of cervical cancer stem cells
    por Yang Y, Yu L, Li J, Yuan YH, Wang XL, Yan SR, Li DS, Ding Y
    Publicado 2017
    “... regulate the expression level of PA proteins in cervical CSCs. In addition, CRISPR/Cas 9-mediated Beclin 1...”
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  4. 984
    Tomato and cotton G protein beta subunit mutants display constitutive autoimmune responses
    “... of functional differences between monocots and dicots. Using CRISPR/Cas9, we produced one hemizygous tomato line...”
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  5. 985
    Wnt-inducible Lrp6-APEX2 interacting proteins identify ESCRT machinery and Trk-fused gene as components of the Wnt signaling pathway
    “... in the proximity of Lrp6. TFG depletion with siRNA, or knock-out with CRISPR/Cas9, significantly reduced Wnt/β...”
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  6. 986
    Screen and Verification for Transgene Integration Sites in Pigs
    “... potential non-coding RNAs. After CRISPR/Cas9-mediated site-specific integration on Pifs501, we detected high...”
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  7. 987
    Downregulation of E-cadherin in pluripotent stem cells triggers partial EMT
    “.... In this work, using a CRISPR interference system in human embryonic stem cells, we describe a molecular...”
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  8. 988
    Disruption of the odorant coreceptor Orco impairs foraging and host finding behaviors in the New World screwworm fly
    “..., and behavioral aspects of the screwworm biology. We used CRISPR/Cas9 to disrupt ChomOrco and evaluate...”
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  9. 989
    A piggyBac-based platform for genome editing and clonal rhesus macaque iPSC line derivation
    “... conditions even after removal of the transgene resulting in transgene-free iPSCs; (3) Development of a CRISPR...”
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  10. 990
    A novel tissue specific alternative splicing variant mitigates phenotypes in Ets2 frame-shift mutant models
    “... mutant models with a frame-shift mutation in exon 8 using the CRISPR/Cas9 method. Homozygous mutants...”
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  11. 991
    Constitutive depletion of Slc34a2/NaPi-IIb in rats causes perinatal mortality
    “... describe the generation of a rat model with Crispr/Cas-driven constitutive depletion of Slc34a2. Slc34a2...”
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  12. 992
    ADAD1 and ADAD2, testis-specific adenosine deaminase domain-containing proteins, are required for male fertility
    “... on male germ cell RNA editing, CRISPR-induced alleles of each were generated in mouse. Mutation of either...”
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  13. 993
    Peculiarities of the Transformation of Asteraceae Family Species: The Cases of Sunflower and Lettuce
    “... editing using the CRISPR system. On the other hand, sunflower (Helianthus annuus L.) is a species...”
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  14. 994
    Genome analysis of environmental and clinical P. aeruginosa isolates from sequence type-1146.
    “...37 (24 genes), P47 (16 genes) and P49 (21 genes). CRISPR elements were found in all isolates and SD9...”
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  15. 995
    Simple and efficient methods for enrichment and isolation of endonuclease modified cells.
    “... such as CRISPR, provide a straightforward and cost effective option for targeted gene knockout (KO). Yet...”
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  16. 996
    Gene Therapy for Cardiovascular Disease: Basic Research and Clinical Prospects
    “... that functioned through protein–nucleic acids complexes—CRISPR/Cas9 system. This holds another promise...”
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  17. 997
    Dual inhibition of TMPRSS2 and Cathepsin Bprevents SARS-CoV-2 infection in iPS cells
    “...) in SARS-CoV-2 infection using the CRISPR interference system and ACE2-expressing human induced pluripotent...”
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  18. 998
    Core circadian clock transcription factor BMAL1 regulates mammary epithelial cell growth, differentiation, and milk component synthesis.
    “... knocked out (BMAL1-KO) using CRISPR-CAS was created. BMAL1-KO cultures had lower cell densities over...”
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  19. 999
    Deletion of a putative promoter-proximal Tnfsf11 regulatory region in mice does not alter bone mass or Tnfsf11 expression in vivo.
    “..., relative to Tnfsf11 exon 1, from mice using CRISPR-based gene editing. MicroCT analysis of the femur...”
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  20. 1000
    Expression and activation of the steroidogenic enzyme CYP11A1 is associated with IL-13 production in T cells from peanut allergic children.
    “... of CYP11A1 on cytokine production was tested using a CYP11A1 CRISPR/Cas9 KO plasmid or an inhibitor...”
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