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3por Giedrius Gasiunas, Joshua K. Young, Tautvydas Karvelis, Darius Kazlauskas, Tomas Urbaitis, Monika Jasnauskaite, Mantvyda M. Grusyte, Sushmitha Paulraj, Po-Hao Wang, Zhenglin Hou, Shane K. Dooley, Mark Cigan, Clara Alarcon, N. Doane Chilcoat, Greta Bigelyte, Jennifer L. Curcuru, Megumu Mabuchi, Zhiyi Sun, Ryan T. Fuchs, Ezra Schildkraut, Peter R. Weigele, William E. Jack, G. Brett Robb, Česlovas Venclovas, Virginijus SiksnysEnlace del recurso
Publicado 2020
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4por Jungjoon K. Lee, Euihwan Jeong, Joonsun Lee, Minhee Jung, Eunji Shin, Young-hoon Kim, Kangin Lee, Inyoung Jung, Daesik Kim, Seokjoong Kim, Jin-Soo Kim“...Undesired off-target effects can hamper the use of CRISPR-Cas9 in therapeutic applications. Here...”
Publicado 2018
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5“... RNA (gRNA) and CRISPR-associated (Cas-9) proteins are the two essential components in CRISPR/Cas-9...”
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7“.... Here, we report efficient generation of F0 knock-in lampreys by CRISPR-Cas9-mediated genome editing. A...”
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8por Kendall R. Sanson, Ruth E. Hanna, Mudra Hegde, Katherine F. Donovan, Christine Strand, Meagan E. Sullender, Emma W. Vaimberg, Amy Goodale, David E. Root, Federica Piccioni, John G. DoenchEnlace del recurso
Publicado 2018
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9por Cong Huai, Gan Li, Ruijie Yao, Yingyi Zhang, Mi Cao, Liangliang Kong, Chenqiang Jia, Hui Yuan, Hongyan Chen, Daru Lu, Qiang Huang“...CRISPR-Cas9 is widely used for genome engineering but structural data for the DNA cleavage step...”
Publicado 2017
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10“...CRISPR-Cas9 has been used to generate a range of genetic modifications including gene knock-outs...”
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11por Alexandra L. Bryson, Young Hwang, Scott Sherrill-Mix, Gary D. Wu, James D. Lewis, Lindsay Black, Tyson A. Clark, Frederic D. Bushman“... phage DNA modifications may also block attack by CRISPR-Cas9. We investigated phage T4 as a model system...”
Publicado 2015
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13por Risa Ueta, Chihiro Abe, Takahito Watanabe, Shigeo S. Sugano, Ryosuke Ishihara, Hiroshi Ezura, Yuriko Osakabe, Keishi Osakabe“... to generate parthenocarpic tomato plants using the CRISPR/Cas9 system. We optimized the CRISPR/Cas9 system...”
Publicado 2017
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14por Jun Wu, Marcela Vilarino, Keiichiro Suzuki, Daiji Okamura, Yanina Soledad Bogliotti, Insung Park, Joan Rowe, Bret McNabb, Pablo Juan Ross, Juan Carlos Izpisua Belmonte“...-Cas9 mediated zygote genome editing enables high efficient production of knockout animals suitable...”
Publicado 2017
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16por Andrey Mikheikin, Anita Olsen, Kevin Leslie, Freddie Russell-Pavier, Andrew Yacoot, Loren Picco, Oliver Payton, Amir Toor, Alden Chesney, James K. Gimzewski, Bud Mishra, Jason Reed“... assembly. Here, the authors use CRISPR-Cas9 and high-speed atomic force microscopy to ‘nanomap’ single...”
Publicado 2017
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17“..., the authors show that the CRISPR-Cas9 nuclease induces both expansions and contractions of the repeat region...”
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20“... sequential transformation method for CRISPR/Cas9-mediated gene targeting in Arabidopsis and demonstrate its...”
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