Peginterferon Lambda-1a for treatment of outpatients with uncomplicated COVID-19: a randomized placebo-controlled trial

por Prasanna Jagannathan, Jason R. Andrews, Hector Bonilla, Haley Hedlin, Karen B. Jacobson, Vidhya Balasubramanian, Natasha Purington, Savita Kamble, Christiaan R. de Vries, Orlando Quintero, Kent Feng, Catherine Ley, Dean Winslow, Jennifer Newberry, Karlie Edwards, Colin Hislop, Ingrid Choong, Yvonne Maldonado, Jeffrey Glenn, Ami Bhatt, Catherine Blish, Taia Wang, Chaitan Khosla, Benjamin A. Pinsky, Manisha Desai, Julie Parsonnet, Upinder Singh
Publicado 2021

A multi-platform flow device for microbial (co-) cultivation and microscopic analysis.

por Matthijn C Hesselman, Dorett I Odoni, Brendan M Ryback, Suzette de Groot, Ruben G A van Heck, Jaap Keijsers, Pim Kolkman, David Nieuwenhuijse, Youri M van Nuland, Erik Sebus, Rob Spee, Hugo de Vries, Marten T Wapenaar, Colin J Ingham, Karin Schroën, Vítor A P Martins dos Santos, Sebastiaan K Spaans, Floor Hugenholtz, Mark W J van Passel
Publicado 2012

Regulatory sites for splicing in human basal ganglia are enriched for disease-relevant information

por Sebastian Guelfi, Karishma D’Sa, Juan A. Botía, Jana Vandrovcova, Regina H. Reynolds, David Zhang, Daniah Trabzuni, Leonardo Collado-Torres, Andrew Thomason, Pedro Quijada Leyton, Sarah A. Gagliano Taliun, Mike A. Nalls, International Parkinson’s Disease Genomics Consortium (IPDGC), UK Brain Expression Consortium (UKBEC), Kerrin S. Small, Colin Smith, Adaikalavan Ramasamy, John Hardy, Michael E. Weale, Mina Ryten
Publicado 2020

Multi-tissue interactions in an integrated three-tissue organ-on-a-chip platform

por Aleksander Skardal, Sean V. Murphy, Mahesh Devarasetty, Ivy Mead, Hyun-Wook Kang, Young-Joon Seol, Yu Shrike Zhang, Su-Ryon Shin, Liang Zhao, Julio Aleman, Adam R. Hall, Thomas D. Shupe, Andre Kleensang, Mehmet R. Dokmeci, Sang Jin Lee, John D. Jackson, James J. Yoo, Thomas Hartung, Ali Khademhosseini, Shay Soker, Colin E. Bishop, Anthony Atala
Publicado 2017

Evolutionary signals of selection on cognition from the great tit genome and methylome

por Veronika N. Laine, Toni I. Gossmann, Kyle M. Schachtschneider, Colin J. Garroway, Ole Madsen, Koen J. F. Verhoeven, Victor de Jager, Hendrik-Jan Megens, Wesley C. Warren, Patrick Minx, Richard P. M. A. Crooijmans, Pádraic Corcoran, The Great Tit HapMap Consortium, Ben C. Sheldon, Jon Slate, Kai Zeng, Kees van Oers, Marcel E. Visser, Martien A. M. Groenen
Publicado 2016

A randomized trial evaluating virus-specific effects of a combination probiotic in children with acute gastroenteritis

por Stephen B. Freedman, Jianling Xie, Alberto Nettel-Aguirre, Xiao-Li Pang, Linda Chui, Sarah Williamson-Urquhart, David Schnadower, Suzanne Schuh, Philip M. Sherman, Bonita E. Lee, Serge Gouin, Ken J. Farion, Naveen Poonai, Katrina F. Hurley, Yuanyuan Qiu, Binal Ghandi, Colin Lloyd, Yaron Finkelstein, the Pediatric Emergency Research Canada Probiotic (PERC) Regimen for Outpatient Gastroenteritis Utility of Treatment (PROGUT) Trial Group
Publicado 2020

Year-Round Movements of Sooty Terns (Onychoprion fuscatus) Nesting Within One of the Atlantic’s Largest Marine Protected Areas

por S. James Reynolds, S. James Reynolds, Colin P. Wearn, B. John Hughes, B. John Hughes, Roger C. Dickey, Lucy J. H. Garrett, Lucy J. H. Garrett, Sean Walls, Fay T. Hughes, Nicola Weber, Nicola Weber, Sam B. Weber, Sam B. Weber, Eliza H. K. Leat, Eliza H. K. Leat, Kenickie Andrews, Kenickie Andrews, Jaime A. Ramos, Vitor H. Paiva
Publicado 2021

The development and structure of the mesentery

por Kevin G. Byrnes, Dara Walsh, Leon G. Walsh, Domhnall M. Coffey, Muhammad F. Ullah, Rosa Mirapeix, Jill Hikspoors, Wouter Lamers, Yi Wu, Xiao-Qin Zhang, Shao-Xiang Zhang, Pieter Brama, Colum P. Dunne, Ian S. O’Brien, Colin B. Peirce, Martin J. Shelly, Tim G. Scanlon, Mary E. Luther, Hugh D. Brady, Peter Dockery, Kieran W. McDermott, J. Calvin Coffey
Publicado 2021

Cardiovascular and Renal Risk Factors and Complications Associated With COVID-19

por Rhian M. Touyz, MBBCh, PhD, Marcus O.E. Boyd, Tomasz Guzik, MD, PhD, Sandosh Padmanabhan, MD, PhD, Linsay McCallum, MBChB, Christian Delles, MD, Patrick B. Mark, MBChB, PhD, John R. Petrie, MBChB, PhD, Francisco Rios, PhD, Augusto C. Montezano, PhD, Robert Sykes, MBChB, BMedSci, Colin Berry, MBChB, PhD
Publicado 2021

2,4-dienoyl-CoA reductase regulates lipid homeostasis in treatment-resistant prostate cancer

por Arnaud Blomme, Catriona A. Ford, Ernest Mui, Rachana Patel, Chara Ntala, Lauren E. Jamieson, Mélanie Planque, Grace H. McGregor, Paul Peixoto, Eric Hervouet, Colin Nixon, Mark Salji, Luke Gaughan, Elke Markert, Peter Repiscak, David Sumpton, Giovanny Rodriguez Blanco, Sergio Lilla, Jurre J. Kamphorst, Duncan Graham, Karen Faulds, Gillian M. MacKay, Sarah-Maria Fendt, Sara Zanivan, Hing Y. Leung
Publicado 2020

A workflow to process 3D+time microscopy images of developing organisms and reconstruct their cell lineage

por Emmanuel Faure, Thierry Savy, Barbara Rizzi, Camilo Melani, Olga Stašová, Dimitri Fabrèges, Róbert Špir, Mark Hammons, Róbert Čúnderlík, Gaëlle Recher, Benoît Lombardot, Louise Duloquin, Ingrid Colin, Jozef Kollár, Sophie Desnoulez, Pierre Affaticati, Benoît Maury, Adeline Boyreau, Jean-Yves Nief, Pascal Calvat, Philippe Vernier, Monique Frain, Georges Lutfalla, Yannick Kergosien, Pierre Suret, Mariana Remešíková, René Doursat, Alessandro Sarti, Karol Mikula, Nadine Peyriéras, Paul Bourgine
Publicado 2016

Comprehensive population-wide analysis of Lynch syndrome in Iceland reveals founder mutations in MSH6 and PMS2

por Sigurdis Haraldsdottir, Thorunn Rafnar, Wendy L. Frankel, Sylvia Einarsdottir, Asgeir Sigurdsson, Heather Hampel, Petur Snaebjornsson, Gisli Masson, Daniel Weng, Reynir Arngrimsson, Birte Kehr, Ahmet Yilmaz, Stefan Haraldsson, Patrick Sulem, Tryggvi Stefansson, Peter G. Shields, Fridbjorn Sigurdsson, Tanios Bekaii-Saab, Pall H. Moller, Margret Steinarsdottir, Kristin Alexiusdottir, Megan Hitchins, Colin C. Pritchard, Albert de la Chapelle, Jon G. Jonasson, Richard M. Goldberg, Kari Stefansson
Publicado 2017

Antarctic sea ice region as a source of biogenic organic nitrogen in aerosols

por Manuel Dall’Osto, Jurgita Ovadnevaite, Marco Paglione, David C. S. Beddows, Darius Ceburnis, Charlotte Cree, Pau Cortés, Marina Zamanillo, Sdena O. Nunes, Gonzalo L. Pérez, Eva Ortega-Retuerta, Mikhail Emelianov, Dolors Vaqué, Cèlia Marrasé, Marta Estrada, M. Montserrat Sala, Montserrat Vidal, Mark F. Fitzsimons, Rachael Beale, Ruth Airs, Matteo Rinaldi, Stefano Decesari, Maria Cristina Facchini, Roy M. Harrison, Colin O’Dowd, Rafel Simó
Publicado 2017

Decreased body mass index in the preclinical stage of autosomal dominant Alzheimer’s disease

por Stephan Müller, Oliver Preische, Hamid R. Sohrabi, Susanne Gräber, Mathias Jucker, Janko Dietzsch, John M. Ringman, Ralph N. Martins, Eric McDade, Peter R. Schofield, Bernardino Ghetti, Martin Rossor, Neill R. Graff-Radford, Johannes Levin, Douglas Galasko, Kimberly A. Quaid, Stephen Salloway, Chengjie Xiong, Tammie Benzinger, Virginia Buckles, Colin L. Masters, Reisa Sperling, Randall J. Bateman, John C. Morris, Christoph Laske
Publicado 2017

ABCC9-related Intellectual disability Myopathy Syndrome is a KATP channelopathy with loss-of-function mutations in ABCC9

por Marie F. Smeland, Conor McClenaghan, Helen I. Roessler, Sanne Savelberg, Geir Åsmund Myge Hansen, Helene Hjellnes, Kjell Arne Arntzen, Kai Ivar Müller, Andreas Rosenberger Dybesland, Theresa Harter, Monica Sala-Rabanal, Chris H. Emfinger, Yan Huang, Soma S. Singareddy, Jamie Gunn, David F. Wozniak, Attila Kovacs, Maarten Massink, Federico Tessadori, Sarah M. Kamel, Jeroen Bakkers, Maria S. Remedi, Marijke Van Ghelue, Colin G. Nichols, Gijs van Haaften
Publicado 2019

The protective role of DOT1L in UV-induced melanomagenesis

por Bo Zhu, Shuyang Chen, Hongshen Wang, Chengqian Yin, Changpeng Han, Cong Peng, Zhaoqian Liu, Lixin Wan, Xiaoyang Zhang, Jie Zhang, Christine G. Lian, Peilin Ma, Zhi-xiang Xu, Sharon Prince, Tao Wang, Xiumei Gao, Yujiang Shi, Dali Liu, Min Liu, Wenyi Wei, Zhi Wei, Jingxuan Pan, Yongjun Wang, Zhenyu Xuan, Jay Hess, Nicholas K. Hayward, Colin R. Goding, Xiang Chen, Jun Zhou, Rutao Cui
Publicado 2018

Vps34 PI 3-kinase inactivation enhances insulin sensitivity through reprogramming of mitochondrial metabolism

por Benoit Bilanges, Samira Alliouachene, Wayne Pearce, Daniele Morelli, Gyorgy Szabadkai, Yuen-Li Chung, Gaëtan Chicanne, Colin Valet, Julia M. Hill, Peter J. Voshol, Lucy Collinson, Christopher Peddie, Khaled Ali, Essam Ghazaly, Vinothini Rajeeve, Georgios Trichas, Shankar Srinivas, Claire Chaussade, Rachel S. Salamon, Jonathan M. Backer, Cheryl L. Scudamore, Maria A. Whitehead, Erin P. Keaney, Leon O. Murphy, Robert K. Semple, Bernard Payrastre, Sharon A. Tooze, Bart Vanhaesebroeck
Publicado 2017

Structure of PDE3A-SLFN12 complex reveals requirements for activation of SLFN12 RNase

por Colin W. Garvie, Xiaoyun Wu, Malvina Papanastasiou, Sooncheol Lee, James Fuller, Gavin R. Schnitzler, Steven W. Horner, Andrew Baker, Terry Zhang, James P. Mullahoo, Lindsay Westlake, Stephanie H. Hoyt, Marcus Toetzl, Matthew J. Ranaghan, Luc de Waal, Joseph McGaunn, Bethany Kaplan, Federica Piccioni, Xiaoping Yang, Martin Lange, Adrian Tersteegen, Donald Raymond, Timothy A. Lewis, Steven A. Carr, Andrew D. Cherniack, Christopher T. Lemke, Matthew Meyerson, Heidi Greulich
Publicado 2021

Concordant peripheral lipidome signatures in two large clinical studies of Alzheimer’s disease

por Kevin Huynh, Wei Ling Florence Lim, Corey Giles, Kaushala S. Jayawardana, Agus Salim, Natalie A. Mellett, Adam Alexander T. Smith, Gavriel Olshansky, Brian G. Drew, Pratishtha Chatterjee, Ian Martins, Simon M. Laws, Ashley I. Bush, Christopher C. Rowe, Victor L. Villemagne, David Ames, Colin L. Masters, Matthias Arnold, Kwangsik Nho, Andrew J. Saykin, Rebecca Baillie, Xianlin Han, Rima Kaddurah-Daouk, Ralph N. Martins, Peter J. Meikle
Publicado 2020

Publisher Correction: 78,000-year-old record of Middle and Later Stone Age innovation in an East African tropical forest

por Ceri Shipton, Patrick Roberts, Will Archer, Simon J. Armitage, Caesar Bita, James Blinkhorn, Colin Courtney-Mustaphi, Alison Crowther, Richard Curtis, Francesco d’ Errico, Katerina Douka, Patrick Faulkner, Huw S. Groucutt, Richard Helm, Andy I. R. Herries, Severinus Jembe, Nikos Kourampas, Julia Lee-Thorp, Rob Marchant, Julio Mercader, Africa Pitarch Marti, Mary E. Prendergast, Ben Rowson, Amini Tengeza, Ruth Tibesasa, Tom S. White, Michael D. Petraglia, Nicole Boivin
Publicado 2018