Norovirus evolution in immunodeficient mice reveals potentiated pathogenicity via a single nucleotide change in the viral capsid.

por Forrest C Walker, Ebrahim Hassan, Stefan T Peterson, Rachel Rodgers, Lawrence A Schriefer, Cassandra E Thompson, Yuhao Li, Gowri Kalugotla, Carla Blum-Johnston, Dylan Lawrence, Broc T McCune, Vincent R Graziano, Larissa Lushniak, Sanghyun Lee, Alexa N Roth, Stephanie M Karst, Timothy J Nice, Jonathan J Miner, Craig B Wilen, Megan T Baldridge
Publicado 2021

Novel regulators of PrPC biosynthesis revealed by genome-wide RNA interference.

por Daniel Heinzer, Merve Avar, Daniel Patrick Pease, Ashutosh Dhingra, Jiang-An Yin, Elke Schaper, Berre Doğançay, Marc Emmenegger, Anna Spinelli, Kevin Maggi, Andra Chincisan, Simon Mead, Simone Hornemann, Peter Heutink, Adriano Aguzzi
Publicado 2021

The regulation landscape of MAPK signaling cascade for thwarting Bacillus thuringiensis infection in an insect host.

por Zhaojiang Guo, Shi Kang, Qingjun Wu, Shaoli Wang, Neil Crickmore, Xuguo Zhou, Alejandra Bravo, Mario Soberón, Youjun Zhang
Publicado 2021

Editorial overview of Pearls Microbiome Series: E pluribus unum.

por Deborah A Hogan, Joseph Heitman, Mary Ann Jabra-Rizk, Laura J Knoll, John M Leong, Neal Silverman
Publicado 2021

A kinase-independent function of PAK is crucial for pathogen-mediated actin remodelling.

por Anthony Davidson, Joe Tyler, Peter Hume, Vikash Singh, Vassilis Koronakis
Publicado 2021

Luteolin as a potential host-directed immunotherapy adjunct to isoniazid treatment of tuberculosis.

por Dhiraj Kumar Singh, Sultan Tousif, Ashima Bhaskar, Annu Devi, Kriti Negi, Barnani Moitra, Anand Ranganathan, Ved Prakash Dwivedi, Gobardhan Das
Publicado 2021

Caenorhabditis elegans N-glycan core beta-galactoside confers sensitivity towards nematotoxic fungal galectin CGL2.

por Alex Butschi, Alexander Titz, Martin A Wälti, Vincent Olieric, Katharina Paschinger, Katharina Nöbauer, Xiaoqiang Guo, Peter H Seeberger, Iain B H Wilson, Markus Aebi, Michael O Hengartner, Markus Künzler
Publicado 2010

Rab11a mediates cell-cell spread and reassortment of influenza A virus genomes via tunneling nanotubes.

por Ketaki Ganti, Julianna Han, Balaji Manicassamy, Anice C Lowen
Publicado 2021

RNF111-facilitated neddylation potentiates cGAS-mediated antiviral innate immune response.

por Chenhui Li, Lele Zhang, Dong Qian, Mingxing Cheng, Haiyang Hu, Ze Hong, Ye Cui, Huansha Yu, Quanyi Wang, Juanjuan Zhu, Wei Meng, Jin-Fu Xu, Yi Sun, Peng Zhang, Chen Wang
Publicado 2021

CXCR6+CD4+ T cells promote mortality during Trypanosoma brucei infection.

por Gongguan Liu, Osama Abas, Ashley B Strickland, Yanli Chen, Meiqing Shi
Publicado 2021

Inhibition of the H3K27 demethylase UTX enhances the epigenetic silencing of HIV proviruses and induces HIV-1 DNA hypermethylation but fails to permanently block HIV reactivation.

por Kien Nguyen, Curtis Dobrowolski, Meenakshi Shukla, Won-Kyung Cho, Benjamin Luttge, Jonathan Karn
Publicado 2021

Cryptococcal cell morphology affects host cell interactions and pathogenicity.

por Laura H Okagaki, Anna K Strain, Judith N Nielsen, Caroline Charlier, Nicholas J Baltes, Fabrice Chrétien, Joseph Heitman, Françoise Dromer, Kirsten Nielsen
Publicado 2010

pUL21 is a viral phosphatase adaptor that promotes herpes simplex virus replication and spread.

por Tomasz H Benedyk, Julia Muenzner, Viv Connor, Yue Han, Katherine Brown, Kaveesha J Wijesinghe, Yunhui Zhuang, Susanna Colaco, Guido A Stoll, Owen S Tutt, Stanislava Svobodova, Dmitri I Svergun, Neil A Bryant, Janet E Deane, Andrew E Firth, Cy M Jeffries, Colin M Crump, Stephen C Graham
Publicado 2021

pUL21 regulation of pUs3 kinase activity influences the nature of nuclear envelope deformation by the HSV-2 nuclear egress complex.

por Jamil H Muradov, Renée L Finnen, Michael A Gulak, Thomas J M Hay, Bruce W Banfield
Publicado 2021

Teaching a new mouse old tricks: Humanized mice as an infection model for Variola virus.

por Christina L Hutson, Ashley V Kondas, Jana M Ritter, Zachary Reed, Sharon Dietz Ostergaard, Clint N Morgan, Nadia Gallardo-Romero, Cassandra Tansey, Matthew R Mauldin, Johanna S Salzer, Christine M Hughes, Cynthia S Goldsmith, Darin Carroll, Victoria A Olson
Publicado 2021

Suppression of inflammatory arthritis by the parasitic worm product ES-62 is associated with epigenetic changes in synovial fibroblasts.

por Marlene Corbet, Miguel A Pineda, Kun Yang, Anuradha Tarafdar, Sarah McGrath, Rinako Nakagawa, Felicity E Lumb, Colin J Suckling, William Harnett, Margaret M Harnett
Publicado 2021

Differential pathogenesis of closely related 2018 Nigerian outbreak clade III Lassa virus isolates.

por Derek R Stein, Bryce M Warner, Jonathan Audet, Geoff Soule, Vinayakumar Siragam, Patrycja Sroga, Bryan D Griffin, Anders Leung, Allen Grolla, Kevin Tierney, Alix Albietz, Darwyn Kobasa, Abdulmajid S Musa, Adama Ahmad, Afolabi M Akinpelu, Nwando Mba, Rebecca Rosenke, Dana P Scott, Greg Saturday, Chikwe Ihekweazu, David Safronetz
Publicado 2021

The pentose phosphate pathway constitutes a major metabolic hub in pathogenic Francisella.

por Héloise Rytter, Anne Jamet, Jason Ziveri, Elodie Ramond, Mathieu Coureuil, Pauline Lagouge-Roussey, Daniel Euphrasie, Fabiola Tros, Nicolas Goudin, Cerina Chhuon, Ivan Nemazanyy, Fabricio Edgar de Moraes, Carlos Labate, Ida Chiara Guerrera, Alain Charbit
Publicado 2021

T cell derived HIV-1 is present in the CSF in the face of suppressive antiretroviral therapy.

por Gila Lustig, Sandile Cele, Farina Karim, Anne Derache, Abigail Ngoepe, Khadija Khan, Bernadett I Gosnell, Mahomed-Yunus S Moosa, Ntombi Ntshuba, Suzaan Marais, Prakash M Jeena, Katya Govender, John Adamson, Henrik Kløverpris, Ravindra K Gupta, Rohen Harrichandparsad, Vinod B Patel, Alex Sigal
Publicado 2021

Entamoeba histolytica activation of caspase-1 degrades cullin that attenuates NF-κB dependent signaling from macrophages.

por Attinder Chadha, France Moreau, Shanshan Wang, Antoine Dufour, Kris Chadee
Publicado 2021