Bordetella adenylate cyclase toxin mobilizes its beta2 integrin receptor into lipid rafts to accomplish translocation across target cell membrane in two steps.

por Ladislav Bumba, Jiri Masin, Radovan Fiser, Peter Sebo
Publicado 2010

Glycoprotein N-linked glycans play a critical role in arenavirus pathogenicity.

por Takaaki Koma, Cheng Huang, Adrian Coscia, Steven Hallam, John T Manning, Junki Maruyama, Aida G Walker, Milagros Miller, Jeanon N Smith, Michael Patterson, Jonathan Abraham, Slobodan Paessler
Publicado 2021

Vaccinia virus proteins A52 and B14 Share a Bcl-2-like fold but have evolved to inhibit NF-kappaB rather than apoptosis.

por Stephen C Graham, Mohammad W Bahar, Samantha Cooray, Ron A-J Chen, Daniel M Whalen, Nicola G A Abrescia, David Alderton, Raymond J Owens, David I Stuart, Geoffrey L Smith, Jonathan M Grimes
Publicado 2008

Hepatitis C virus induces oxidation and degradation of apolipoprotein B to enhance lipid accumulation and promote viral production.

por Bei Wang, Yue Zhu, Congci Yu, Chongyang Zhang, Qing Tang, He Huang, Zhendong Zhao
Publicado 2021

Leprosy and the adaptation of human toll-like receptor 1.

por Sunny H Wong, Sailesh Gochhait, Dheeraj Malhotra, Fredrik H Pettersson, Yik Y Teo, Chiea C Khor, Anna Rautanen, Stephen J Chapman, Tara C Mills, Amit Srivastava, Aleksey Rudko, Maxim B Freidin, Valery P Puzyrev, Shafat Ali, Shweta Aggarwal, Rupali Chopra, Belum S N Reddy, Vijay K Garg, Suchismita Roy, Sarah Meisner, Sunil K Hazra, Bibhuti Saha, Sian Floyd, Brendan J Keating, Cecilia Kim, Benjamin P Fairfax, Julian C Knight, Philip C Hill, Richard A Adegbola, Hakon Hakonarson, Paul E M Fine, Ramasamy M Pitchappan, Rameshwar N K Bamezai, Adrian V S Hill, Fredrik O Vannberg
Publicado 2010

Activation of Akt signaling reduces the prevalence and intensity of malaria parasite infection and lifespan in Anopheles stephensi mosquitoes.

por Vanessa Corby-Harris, Anna Drexler, Laurel Watkins de Jong, Yevgeniya Antonova, Nazzy Pakpour, Rolf Ziegler, Frank Ramberg, Edwin E Lewis, Jessica M Brown, Shirley Luckhart, Michael A Riehle
Publicado 2010

Equine rhinitis A virus and its low pH empty particle: clues towards an aphthovirus entry mechanism?

por Tobias J Tuthill, Karl Harlos, Thomas S Walter, Nick J Knowles, Elisabetta Groppelli, David J Rowlands, David I Stuart, Elizabeth E Fry
Publicado 2009

CXCL1: A new diagnostic biomarker for human tuberculosis discovered using Diversity Outbred mice.

por Deniz Koyuncu, Muhammad Khalid Khan Niazi, Thomas Tavolara, Claudia Abeijon, Melanie L Ginese, Yanghui Liao, Carolyn Mark, Aubrey Specht, Adam C Gower, Blanca I Restrepo, Daniel M Gatti, Igor Kramnik, Metin Gurcan, Bülent Yener, Gillian Beamer
Publicado 2021

Role of PKR and Type I IFNs in viral control during primary and secondary infection.

por Yumi Nakayama, Erin H Plisch, Jeremy Sullivan, Chester Thomas, Charles J Czuprynski, Bryan R G Williams, M Suresh
Publicado 2010

Low-dose IL-2 therapy invigorates CD8+ T cells for viral control in systemic lupus erythematosus.

por Pengcheng Zhou, Jiali Chen, Jing He, Ting Zheng, Joseph Yunis, Victor Makota, Yannick O Alexandre, Fang Gong, Xia Zhang, Wuxiang Xie, Yuhui Li, Miao Shao, Yanshan Zhu, Jane E Sinclair, Miao Miao, Yaping Chen, Kirsty R Short, Scott N Mueller, Xiaolin Sun, Di Yu, Zhanguo Li
Publicado 2021

Trypanosoma brucei triggers a broad immune response in the adipose tissue.

por Henrique Machado, Tiago Bizarra-Rebelo, Mariana Costa-Sequeira, Sandra Trindade, Tânia Carvalho, Filipa Rijo-Ferreira, Barbara Rentroia-Pacheco, Karine Serre, Luisa M Figueiredo
Publicado 2021

Intracellular proton conductance of the hepatitis C virus p7 protein and its contribution to infectious virus production.

por Ann L Wozniak, Stephen Griffin, David Rowlands, Mark Harris, MinKyung Yi, Stanley M Lemon, Steven A Weinman
Publicado 2010

Myeloid neddylation targets IRF7 and promotes host innate immunity against RNA viruses.

por Min Zhao, Yaolin Zhang, Xiqin Yang, Jiayang Jin, Zhuo Shen, Xiaoyao Feng, Tao Zou, Lijiao Deng, Daohai Cheng, Xueting Zhang, Cheng Qin, Chunxiao Niu, Zhenjie Ye, Xueying Zhang, Jia He, Chunmei Hou, Ge Li, Gencheng Han, Qianqian Cheng, Qingyang Wang, Lin Wei, Jie Dong, Jiyan Zhang
Publicado 2021

Parasitic nematode fatty acid- and retinol-binding proteins compromise host immunity by interfering with host lipid signaling pathways.

por Sophia C Parks, Susan Nguyen, Shyon Nasrolahi, Chaitra Bhat, Damian Juncaj, Dihong Lu, Raghavendran Ramaswamy, Harpal Dhillon, Hideji Fujiwara, Anna Buchman, Omar S Akbari, Naoki Yamanaka, Martin J Boulanger, Adler R Dillman
Publicado 2021

Comparison of transcriptional profiles of Treponema pallidum during experimental infection of rabbits and in vitro culture: Highly similar, yet different.

por Bridget D De Lay, Todd A Cameron, Nicholas R De Lay, Steven J Norris, Diane G Edmondson
Publicado 2021

Elevated cytokines and chemokines in peripheral blood of patients with SARS-CoV-2 pneumonia treated with high-titer convalescent plasma.

por Stacey L Fanning, Robert Korngold, Zheng Yang, Kira Goldgirsh, Steven Park, Joshua Zenreich, Melissa Baker, Phyllis McKiernan, Ming Tan, Bingsong Zhang, Michele L Donato, David S Perlin
Publicado 2021

Cell-to-cell transmission of HSV1 in human keratinocytes in the absence of the major entry receptor, nectin1.

por Joanne Kite, Tiffany Russell, Juliet Jones, Gillian Elliott
Publicado 2021

Phagocytes produce prostaglandin E2 in response to cytosolic Listeria monocytogenes.

por Courtney E McDougal, Zachary T Morrow, Tighe Christopher, Seonyoung Kim, Drake Carter, David M Stevenson, Daniel Amador-Noguez, Mark J Miller, John-Demian Sauer
Publicado 2021

Heparan sulfate proteoglycans serve as alternative receptors for low affinity LCMV variants.

por André Volland, Michael Lohmüller, Emmanuel Heilmann, Janine Kimpel, Sebastian Herzog, Dorothee von Laer
Publicado 2021

Nasal therapy-The missing link in optimising strategies to improve prevention and treatment of COVID-19.

por Norman A Ratcliffe, Helena C Castro, Izabel C Paixão, Victor G O Evangelho, Patricia Azambuja, Cicero B Mello
Publicado 2021