Showing 1 - 20 results of 50 for search '"Diseases."', query time: 0.04s Refine Results
  1. 1
    An excerpt of Budd-Chiari syndrome: Consensus guidance of the Asian Pacific Association for the Study of the Liver (APASL)
    by WANG Xueying
    Published 2021
    Subjects: “...Diseases of the digestive system. Gastroenterology...”
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  2. 2
    ObjectiveTo establish a nomogram for predicting the risk of post-hepatectomy complications (PHC) in hepatic echinococcosis by analyzing the risk factors for PHC in two types of hepatic echinococcosis, and to investigate its value in clinical practice. MethodsA retrospective analysis was performed for the clinical data of 263 patients with two types of hepatic echinococcosis who underwent hepatectomy in Qinghai University Affiliated Hospital from January 2015 to August 2020, and among these patients, 93 were enrolled as PHC group and 170 were enrolled as control group. The Mann-Whitney U test was used for comparison of non-normally distributed continuous data between two groups, and the independent samples t-test was used for comparison of normally distributed continuous data between two groups; the chi-square test and the Fisher’s exact test were used for comparison of categorical data between two groups. Univariate and multivariate logistic regression analyses were used to screen out independent risk factors for PHC, and a nomogram risk prediction model was established based on the weight of each independent risk factor. The Bootstrap resampling method was used for internal verification of the model; the receiver operating characteristic (ROC) curve was plotted to evaluate the discriminatory ability of the model; calibration curve and the Hosmer-Lemeshow test were used to evaluate the consistency of the model; decision curve analysis (DCA) was performed to verify the clinical effectiveness of the model. ResultsAlbumin-bilirubin (ALBI) score (odds ratio ［OR］=3.694, 95% confidence interval ［CI］: 1.860-7336, P＜0.05), time of operation (OR=2.848, 95%CI: 1.384-5.859, P＜0.05), intraoperative blood loss (OR=4.832, 95%CI: 2.384-9.793, P＜0.05), and hydatid diameter (OR=3.073, 95%CI: 1.528-6.177, P＜0.05) were independent risk factors for PHC in two types of hepatic echinococcosis. A nomogram risk prediction model was established based on the weight of the above four independent risk factors, and the model had an area under the ROC curve of 0.877 (95%CI: 0.831-0.923). The model had a consistency index of 0.871 after internal verification using the Bootstrap resampling method, suggesting that the model had good discriminatory ability. The fitting of the observed value and the actual value of the calibration curve and the Hosmer-Lemeshow test (P=0.905) showed that the predicted value of the nomogram risk prediction model had good consistency with the actual observed value. When the threshold probability was 35.6%, DCA showed a net clinical benefit of 22%, and the model had good clinical applicability within the threshold probability ranging from 8% to 89%. ConclusionALBI score, time of operation, intraoperative blood loss, and hydatid diameter are independent risk factors for PHC in patients with two types of hepatic echinococcosis, and the nomogram risk prediction model established based on these factors has good accuracy, consistency, and clinical practicability.
    by LI Hongye
    Published 2021
    Subjects: “...Diseases of the digestive system. Gastroenterology...”
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  3. 3
    Antiviral therapy for chronic hepatitis B in the indeterminate phase is urgent
    by JIANG Jun
    Published 2021
    Subjects: “...Diseases of the digestive system. Gastroenterology...”
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  4. 4
    Establishment and evaluation of a nomogram for predicting post-hepatectomy complications in two types of hepatic echinococcosis
    by GUO Bing
    Published 2021
    Subjects: “...Diseases of the digestive system. Gastroenterology...”
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  5. 5
    Patients with chronic hepatitis B virus infection in the indeterminate phase may benefit from antiviral therapy
    by XU Jinghang
    Published 2021
    Subjects: “...Diseases of the digestive system. Gastroenterology...”
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  6. 6
    Association between liver fibrosis progression and endothelin-1/nitric oxide in patients with nonalcoholic fatty liver disease
    by LI Pinhua
    Published 2021
    Subjects: “...Diseases of the digestive system. Gastroenterology...”
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  7. 7
    Value of albumin-bilirubin grade in predicting liver function changes and prognosis of hepatocellular carcinoma patients undergoing transarterial chemoembolization: A Meta-analysis
    by YU Weiming
    Published 2021
    Subjects: “...Diseases of the digestive system. Gastroenterology...”
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  8. 8
    Pathological features and pathological diagnosis of drug-induced liver injury
    by YANG Yongfeng
    Published 2021
    Subjects: “...Diseases of the digestive system. Gastroenterology...”
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  9. 9
    Effect of atractylone on the viability and apoptosis of hepatoma HepG2 cells and related mechanism
    by YANG Xueli
    Published 2021
    Subjects: “...Diseases of the digestive system. Gastroenterology...”
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  10. 10
    Clinical features and prognosis of primary myelofibrosis with hepatic vascular disease and/or portal hypertension
    by WANG Jing
    Published 2021
    Subjects: “...Diseases of the digestive system. Gastroenterology...”
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  11. 11
    A preliminary study on percutaneous transhepatic drainage combined with sequential percutaneous nephroscopy in treatment of refractory liver abscess
    by DUAN Changhu
    Published 2021
    Subjects: “...Diseases of the digestive system. Gastroenterology...”
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  12. 12
    Effectiveness and safety of two-step percutaneous transhepatic choledochoscopic lithotomy in treatment of complex hepatolithiasis
    by DUAN Changhu
    Published 2021
    Subjects: “...Diseases of the digestive system. Gastroenterology...”
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  13. 13
    Patients in the indeterminate phase of chronic hepatitis B virus infection should receive active antiviral therapy
    by WANG Jingyue
    Published 2021
    Subjects: “...Diseases of the digestive system. Gastroenterology...”
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  14. 14
    Clinical manifestations and typing of drug-induced liver injury
    by YANG Wanna
    Published 2021
    Subjects: “...Diseases of the digestive system. Gastroenterology...”
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  15. 15
    Construction of a new patient-derived xenograft model of human liver cancer in mice with normal immunity
    by TANG Huixin
    Published 2021
    Subjects: “...Diseases of the digestive system. Gastroenterology...”
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  16. 16
    Risk factors for rebleeding after endoscopic selective variceal devascularization in patients with hepatitis B cirrhosis and acute variceal bleeding
    by MA Jiali
    Published 2021
    Subjects: “...Diseases of the digestive system. Gastroenterology...”
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  17. 17
    An excerpt of diagnosis, evaluation, and management of ascites and hepatorenal syndrome: 2021 Practice Guidance by the American Association for the Study of Liver Diseases
    by HU Jiaxuan
    Published 2021
    Subjects: “...Diseases of the digestive system. Gastroenterology...”
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  18. 18
    Epidemiology of drug-induced liver injury
    by LI Xiaoyun
    Published 2021
    Subjects: “...Diseases of the digestive system. Gastroenterology...”
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  19. 19
    A serum metabolomics study on the intervention of nonalcoholic fatty liver disease by equicaloric low-carbohydrate high-protein diet combined with aerobic exercise
    by LI Meiying
    Published 2021
    Subjects: “...Diseases of the digestive system. Gastroenterology...”
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  20. 20
    Clinical features of drug-induced liver failure and related diagnosis and treatment strategies
    by LAI Rongtao
    Published 2021
    Subjects: “...Diseases of the digestive system. Gastroenterology...”
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