Muscle-specific CRISPR/Cas9 dystrophin gene editing ameliorates pathophysiology in a mouse model for Duchenne muscular dystrophy

por Niclas E. Bengtsson, John K. Hall, Guy L. Odom, Michael P. Phelps, Colin R. Andrus, R. David Hawkins, Stephen D. Hauschka, Joel R. Chamberlain, Jeffrey S. Chamberlain
Publicado 2017

Loss of Asxl2 leads to myeloid malignancies in mice

por Jianping Li, Fuhong He, Peng Zhang, Shi Chen, Hui Shi, Yanling Sun, Ying Guo, Hui Yang, Na Man, Sarah Greenblatt, Zhaomin Li, Zhengyu Guo, Yuan Zhou, Lan Wang, Lluis Morey, Sion Williams, Xi Chen, Qun-Tian Wang, Stephen D. Nimer, Peng Yu, Qian-Fei Wang, Mingjiang Xu, Feng-Chun Yang
Publicado 2017

Pre-fusion RSV F strongly boosts pre-fusion specific neutralizing responses in cattle pre-exposed to bovine RSV

por Ann-Muriel Steff, James Monroe, Kristian Friedrich, Sumana Chandramouli, Thi Lien-Anh Nguyen, Sai Tian, Sarah Vandepaer, Jean-François Toussaint, Andrea Carfi
Publicado 2017

MTHFD1 controls DNA methylation in Arabidopsis

por Martin Groth, Guillaume Moissiard, Markus Wirtz, Haifeng Wang, Carolina Garcia-Salinas, Perla A. Ramos-Parra, Sylvain Bischof, Suhua Feng, Shawn J. Cokus, Amala John, Danielle C. Smith, Jixian Zhai, Christopher J. Hale, Jeff A. Long, Ruediger Hell, Rocío I. Díaz de la Garza, Steven E. Jacobsen
Publicado 2016

Inflammatory monocytes promote pre-engraftment syndrome and tocilizumab can therapeutically limit pathology in patients

por Linlin Jin, Zimin Sun, Huilan Liu, Xiaoyu Zhu, Yonggang Zhou, Binqing Fu, Xiaohu Zheng, Kaidi Song, Baolin Tang, Yun Wu, Jiang Zhu, Rui Sun, Zhigang Tian, Haiming Wei
Publicado 2021

Temporal inhibition of autophagy reveals segmental reversal of ageing with increased cancer risk

por Liam D. Cassidy, Andrew R. J. Young, Christopher N. J. Young, Elizabeth J. Soilleux, Edward Fielder, Bettina M. Weigand, Anthony Lagnado, Rebecca Brais, Nicholas T. Ktistakis, Kimberley A. Wiggins, Katerina Pyrillou, Murray C. H. Clarke, Diana Jurk, Joao F. Passos, Masashi Narita
Publicado 2020

Mps1 kinase-dependent Sgo2 centromere localisation mediates cohesin protection in mouse oocyte meiosis I

por Warif El Yakoubi, Eulalie Buffin, Damien Cladière, Yulia Gryaznova, Inés Berenguer, Sandra A. Touati, Rocío Gómez, José A. Suja, Jan M. van Deursen, Katja Wassmann
Publicado 2017

Urinary tract colonization is enhanced by a plasmid that regulates uropathogenic Acinetobacter baumannii chromosomal genes

por Gisela Di Venanzio, Ana L. Flores-Mireles, Juan J. Calix, M. Florencia Haurat, Nichollas E. Scott, Lauren D. Palmer, Robert F. Potter, Michael E. Hibbing, Laura Friedman, Bin Wang, Gautam Dantas, Eric P. Skaar, Scott J. Hultgren, Mario F. Feldman
Publicado 2019

Stroma remodeling and reduced cell division define durable response to PD-1 blockade in melanoma

por Elena Galvani, Piyushkumar A. Mundra, Sara Valpione, Pablo Garcia-Martinez, Matthew Smith, Jonathan Greenall, Rohit Thakur, Beth Helmink, Miles C. Andrews, Louis Boon, Christopher Chester, Gabriela Gremel, Kate Hogan, Amit Mandal, Kang Zeng, Antonia Banyard, Garry Ashton, Martin Cook, Paul Lorigan, Jennifer A. Wargo, Nathalie Dhomen, Richard Marais
Publicado 2020

BCL-XL directly modulates RAS signalling to favour cancer cell stemness

por Sophie de Carné Trécesson, Frédérique Souazé, Agnès Basseville, Anne-Charlotte Bernard, Jessie Pécot, Jonathan Lopez, Margaux Bessou, Kristopher A. Sarosiek, Anthony Letai, Sophie Barillé-Nion, Isabelle Valo, Olivier Coqueret, Catherine Guette, Mario Campone, Fabien Gautier, Philippe Paul Juin
Publicado 2017

Virulent coliphages in 1-year-old children fecal samples are fewer, but more infectious than temperate coliphages

por Aurélie Mathieu, Moïra Dion, Ling Deng, Denise Tremblay, Elisabeth Moncaut, Shiraz A. Shah, Jakob Stokholm, Karen A. Krogfelt, Susanne Schjørring, Hans Bisgaard, Dennis S. Nielsen, Sylvain Moineau, Marie-Agnès Petit
Publicado 2020

Melanoblast transcriptome analysis reveals pathways promoting melanoma metastasis

por Kerrie L. Marie, Antonella Sassano, Howard H. Yang, Aleksandra M. Michalowski, Helen T. Michael, Theresa Guo, Yien Che Tsai, Allan M. Weissman, Maxwell P. Lee, Lisa M. Jenkins, M. Raza Zaidi, Eva Pérez-Guijarro, Chi-Ping Day, Kris Ylaya, Stephen M. Hewitt, Nimit L. Patel, Heinz Arnheiter, Sean Davis, Paul S. Meltzer, Glenn Merlino, Pravin J. Mishra
Publicado 2020

Endothelial cell clonal expansion in the development of cerebral cavernous malformations

por Matteo Malinverno, Claudio Maderna, Abdallah Abu Taha, Monica Corada, Fabrizio Orsenigo, Mariaelena Valentino, Federica Pisati, Carmela Fusco, Paolo Graziano, Monica Giannotta, Qing Cissy Yu, Yi Arial Zeng, Maria Grazia Lampugnani, Peetra U. Magnusson, Elisabetta Dejana
Publicado 2019

Liver-target nanotechnology facilitates berberine to ameliorate cardio-metabolic diseases

por Hui-Hui Guo, Chen-Lin Feng, Wen-Xuan Zhang, Zhi-Gang Luo, Hong-Juan Zhang, Ting-Ting Zhang, Chen Ma, Yun Zhan, Rui Li, Song Wu, Zeper Abliz, Cong Li, Xiao-Lin Li, Xiao-Lei Ma, Lu-Lu Wang, Wen-Sheng Zheng, Yan-Xing Han, Jian-Dong Jiang
Publicado 2019

TurboID-based proximity labeling reveals that UBR7 is a regulator of N NLR immune receptor-mediated immunity

por Yongliang Zhang, Gaoyuan Song, Neeraj K. Lal, Ugrappa Nagalakshmi, Yuanyuan Li, Wenjie Zheng, Pin-jui Huang, Tess C. Branon, Alice Y. Ting, Justin W. Walley, Savithramma P. Dinesh-Kumar
Publicado 2019

Hyperactivation of HER2-SHCBP1-PLK1 axis promotes tumor cell mitosis and impairs trastuzumab sensitivity to gastric cancer

por Wengui Shi, Gengyuan Zhang, Zhijian Ma, Lianshun Li, Miaomiao Liu, Long Qin, Zeyuan Yu, Lei Zhao, Yang Liu, Xue Zhang, Junjie Qin, Huili Ye, Xiangyan Jiang, Huinian Zhou, Hui Sun, Zuoyi Jiao
Publicado 2021

Sterol O-acyltransferase 2 chaperoned by apolipoprotein J facilitates hepatic lipid accumulation following viral and nutrient stresses

por Hung-Yu Sun, Tzu-Ying Chen, Yu-Ching Tan, Chun-Hsiang Wang, Kung-Chia Young
Publicado 2021

Hepatitis B virus persistence in mice reveals IL-21 and IL-33 as regulators of viral clearance

por Zhongliang Shen, Huijuan Yang, Sisi Yang, Wei Wang, Xiaoxian Cui, Xian Zhou, Wei Liu, Shaokun Pan, Yanfeng Liu, Junqi Zhang, Jiming Zhang, Youhua Xie, Jing Liu
Publicado 2017

Selective hematopoietic stem cell ablation using CD117-antibody-drug-conjugates enables safe and effective transplantation with immunity preservation

por Agnieszka Czechowicz, Rahul Palchaudhuri, Amelia Scheck, Yu Hu, Jonathan Hoggatt, Borja Saez, Wendy W. Pang, Michael K. Mansour, Tiffany A. Tate, Yan Yi Chan, Emily Walck, Gerlinde Wernig, Judith A. Shizuru, Florian Winau, David T. Scadden, Derrick J. Rossi
Publicado 2019

The detection dogs test is more sensitive than real-time PCR in screening for SARS-CoV-2

por Mohammed Hag-Ali, Abdul Salam AlShamsi, Linda Boeijen, Yasser Mahmmod, Rashid Manzoor, Harry Rutten, Marshal M. Mweu, Mohamed El-Tholoth, Abdullatif Alteraifi AlShamsi
Publicado 2021