A New Induction Method for the Controlled Differentiation of Human-Induced Pluripotent Stem Cells Using Frozen Sections

por Susumu Tadokoro, Reiko Tokuyama-Toda, Seiko Tatehara, Shinji Ide, Hirochika Umeki, Keiko Miyoshi, Takafumi Noma, Kazuhito Satomura
Publicado 2021

iPSC-Derived Gaucher Macrophages Display Growth Impairment and Activation of Inflammation-Related Cell Death

por Daria Messelodi, Salvatore Nicola Bertuccio, Valentina Indio, Silvia Strocchi, Alberto Taddia, Salvatore Serravalle, Jessica Bandini, Annalisa Astolfi, Andrea Pession
Publicado 2021

Characterization of the molecular mechanisms underlying azithromycin‐induced cardiotoxicity using human‐induced pluripotent stem cell‐derived cardiomyocytes

por Xiaochen Wang, Ziwei Pan, Jue Wang, Hongkun Wang, Hangping Fan, Tingyu Gong, Qiming Sun, Ye Feng, Ping Liang
Publicado 2021

The Perspectives of Early Diagnosis of Schizophrenia Through the Detection of Epigenomics-Based Biomarkers in iPSC-Derived Neurons

por Davin Lee, Jinsoo Seo, Hae chan Jeong, Hyosang Lee, Sung Bae Lee
Publicado 2021

Mesenchymal Stem Cell Induced Foxp3(+) Tregs Suppress Effector T Cells and Protect against Retinal Ischemic Injury

por Mona Agrawal, Pratheepa Kumari Rasiah, Amandeep Bajwa, Johnson Rajasingh, Rajashekhar Gangaraju
Publicado 2021

Generation of an iPSC line (SMCPGi001-A) from a patient with Bain type X-linked mental retardation syndrome carrying HNRNPH2 gene mutation

por Xiuwei Ma, Lina Zhu, Wangyang Chen, Min Sheng, Fujun Peng, Ming Liang, Yuxiang Zhao, Yongxia Wang, Zhichun Feng
Publicado 2021

iPSC-Derived Microglia as a Model to Study Inflammation in Idiopathic Parkinson’s Disease

por Katja Badanjak, Patrycja Mulica, Semra Smajic, Sylvie Delcambre, Leon-Charles Tranchevent, Nico Diederich, Thomas Rauen, Jens C. Schwamborn, Enrico Glaab, Sally A. Cowley, Paul M. A. Antony, Paul M. A. Antony, Sandro L. Pereira, Carmen Venegas, Anne Grünewald, Anne Grünewald
Publicado 2021

Energy Metabolism and Intracellular pH Alteration in Neural Spheroids Carrying Down Syndrome

por Alena Kashirina, Alena Gavrina, Emil Kryukov, Vadim Elagin, Yuliya Kolesova, Alexander Artyuhov, Ekaterina Momotyuk, Vepa Abdyyev, Natalia Meshcheryakova, Elena Zagaynova, Erdem Dashinimaev, Aleksandra Kashina
Publicado 2021

CRISPR-targeted genome editing of human induced pluripotent stem cell-derived hepatocytes for the treatment of Wilson’s disease

por Rui Wei, Jiayin Yang, Chi-Wa Cheng, Wai-In Ho, Na Li, Yang Hu, Xueyu Hong, Jian Fu, Bo Yang, Yuqing Liu, Lixiang Jiang, Wing-Hon Lai, Ka-Wing Au, Wai-Ling Tsang, Yiu-Lam Tse, Kwong-Man Ng, Miguel A. Esteban, Hung-Fat Tse
Publicado 2022

CXCR2 increases in ALS cortical neurons and its inhibition prevents motor neuron degeneration in vitro and improves neuromuscular function in SOD1G93A mice

por Valentina La Cognata, Elisabetta Golini, Rosario Iemmolo, Sara Balletta, Giovanna Morello, Carla De Rosa, Ambra Villari, Sara Marinelli, Valentina Vacca, Gabriele Bonaventura, Paola Dell'Albani, Eleonora Aronica, Fabio Mammano, Silvia Mandillo, Sebastiano Cavallaro
Publicado 2021

Real-Time Monitoring of Levetiracetam Effect on the Electrophysiology of an Heterogenous Human iPSC-Derived Neuronal Cell Culture Using Microelectrode Array Technology

por Andrea Di Credico, Giulia Gaggi, Pascal Izzicupo, Laura Ferri, Laura Bonanni, Giovanni Iannetti, Angela Di Baldassarre, Barbara Ghinassi
Publicado 2021

Functional Recellularization of Acellular Rat Liver Scaffold by Induced Pluripotent Stem Cells: Molecular Evidence for Wnt/B-Catenin Upregulation

por Nesrine Ebrahim, Omnia A. M. Badr, Mohamed M. Yousef, Amira Hassouna, Dina Sabry, Ayman Samir Farid, Ola Mostafa, Hajir A. Al Saihati, Yasmin Seleem, Eman Abd El Aziz, Ahmed Hassan Khalil, Ahmed Nawar, Ahmed A. Shoulah, Mohammad Aljasir, Amira Zaki Mohamed, Mohamed El-Sherbiny, Nehal M. Elsherbiny, Mohamed Ahmed Eladl, Nicholas Robert Forsyth, Rabab F. Salim
Publicado 2021

Genome-wide differential expression profiling of lncRNAs and mRNAs in human induced pluripotent stem cell-derived endothelial cells exposed to e-cigarette extract

por Hoai Huong Thi Le, Chen-wei Liu, Philip Denaro, Jordan Jousma, Ning-Yi Shao, Irfan Rahman, Won Hee Lee
Publicado 2021

Human Erbb2-induced Erk activity robustly stimulates cycling and functional remodeling of rat and human cardiomyocytes

por Nicholas Strash, Sophia DeLuca, Geovanni L Janer Carattini, Soon Chul Heo, Ryne Gorsuch, Nenad Bursac
Publicado 2021

Isoform-Specific Effects of Apolipoprotein E on Hydrogen Peroxide-Induced Apoptosis in Human Induced Pluripotent Stem Cell (iPSC)-Derived Cortical Neurons

por Huiling Gao, Wei Zheng, Cheng Li, He Xu
Publicado 2021

Long-Term Transplant Effects of iPSC-RPE Monolayer in Immunodeficient RCS Rats

por Deepthi S. Rajendran Nair, Danhong Zhu, Ruchi Sharma, Juan Carlos Martinez Camarillo, Kapil Bharti, David R. Hinton, Mark S. Humayun, Biju B. Thomas
Publicado 2021

Functional dynamic genetic effects on gene regulation are specific to particular cell types and environmental conditions

por Anthony S Findley, Alan Monziani, Allison L Richards, Katherine Rhodes, Michelle C Ward, Cynthia A Kalita, Adnan Alazizi, Ali Pazokitoroudi, Sriram Sankararaman, Xiaoquan Wen, David E Lanfear, Roger Pique-Regi, Yoav Gilad, Francesca Luca
Publicado 2021

Schizophrenia; Recent Cognitive and Treatment Approaches Using Induced Pluripotent Stem Cells

por Nassim Rastgar
Publicado 2020

Orai1–STIM1 Regulates Increased Ca²⁺ Mobilization, Leading to Contractile Duchenne Muscular Dystrophy Phenotypes in Patient-Derived Induced Pluripotent Stem Cells

por Tomoya Uchimura, Hidetoshi Sakurai
Publicado 2021

Enhanced chromatin accessibility contributes to X chromosome dosage compensation in mammals

por Irene Talon, Adrian Janiszewski, Bart Theeuwes, Thomas Lefevre, Juan Song, Greet Bervoets, Lotte Vanheer, Natalie De Geest, Suresh Poovathingal, Ryan Allsop, Jean-Christophe Marine, Florian Rambow, Thierry Voet, Vincent Pasque
Publicado 2021