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  1. 4481
    Immune-checkpoint protein VISTA critically regulates the IL-23/IL-17 inflammatory axis
    “... signaling in Vsir −/− dendritic cells (DCs) led to the hyper-activation of Erk1/2 and Jnk1/2, and augmented...”
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  2. 4482
    SMART Markers: collecting patient-generated health data as a standardized property of health information technology
    “... for patient-led data submission excludes valuable data from digital devices that can potentially aid...”
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  3. 4483
    Salmonella nomenclature in the genomic era: a time for change
    “... scheme has led to the definition of over 2500 serovars which are well understood, have standing...”
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  4. 4484
    Systematic learning in water governance: insights from five local adaptive management projects for water quality innovation
    “..., of which four led to innovations in the small-scale management of waterways in northern Germany. We trace...”
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  5. 4485
    Scalable and accurate deep learning with electronic health records
    “... patient’s entire raw electronic health record (EHR). A team led by Alvin Rajkomar and Eyal Oren from Google...”
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  6. 4486
    Vitamin D receptor upregulates lncRNA TOPORS-AS1 which inhibits the Wnt/β-catenin pathway and associates with favorable prognosis of ovarian cancer
    “... with ovarian cancer outcomes. Our search led to the discovery of lncRNA TOPORS Antisense RNA 1 (TOPORS-AS1...”
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  7. 4487
    Novel Therapies for Metastatic Non-Small Cell Lung Cancer with MET Exon 14 Alterations: A Spotlight on Capmatinib
    por Tan AC, Loh TJ, Kwang XL, Tan GS, Lim KH, Tan DSW
    Publicado 2021
    “...-treated settings and have led to regulatory approvals. This review will focus on practical diagnostic...”
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  8. 4488
    Combination of a T cell activating therapy and anti-phosphatidylserine enhances anti-tumour immune responses in a HPV16 E7-expressing C3 tumour model
    “... compared to untreated controls. All treatments containing DPX-R9F led to T cell activation as assessed...”
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  9. 4489
    Spent coffee ground characterization, pelletization test and emissions assessment in the combustion process
    “...Abstract Industrial development and increased energy requirements have led to high consumption...”
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  10. 4490
    Signatures of white-matter microstructure degradation during aging and its association with cognitive status
    “... integrity in aging. This led to the formulation of a “disconnection hypothesis” in the aging-brain, which...”
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  11. 4491
    Topographical mapping of the mechanical characteristics of the human neurocranium considering the role of individual layers
    “... of diploë attached to outer and inner tables led to a significant reduction in bending strength (with diploë...”
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  12. 4492
    Consumer behavior and customer relationship management in mental health services
    por Lena Bucatariu, Babu George
    Publicado 2020
    “... included about 250 peer-reviewed articles on the topic under consideration. We find that doctor-led service...”
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  13. 4493
    Short-Term Efficacy of Calcium Fructoborate on Subjects with Knee Discomfort: a Comparative, Double-Blind, Placebo-Controlled Clinical Study [Corrigendum]
    “... helped in the data analysis and data compilation. Tania Reyes-Izquierdo led the manuscript writing...”
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  14. 4494
    The serotonin reuptake inhibitor Fluoxetine inhibits SARS-CoV-2 in human lung tissue
    “... inhibitors of SARS-CoV-2, has led to the discovery of Remdesivir. We decided to follow this path and screened...”
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  15. 4495
    Conformational Analysis of Diterpene Lactone Andrographolide towards Reestablishment of Its Absolute Configuration via Theoretical and Experimental ECD and VCD Methods
    “... with 6-31G(d,p) basis set. Long-range exciton coupling of 2-naphthoyl chromophores at C-14 and C-19 led...”
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  16. 4496
    High frequency SD-OCT follow-up leading to up to biweekly intravitreal ranibizumab treatment in neovascular age-related macular degeneration
    “...–6), biweekly (month 7–12)) throughout the first year, which consequently led to intravitreal...”
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  17. 4497
    NADPH oxidase 4 is required for the generation of macrophage migration inhibitory factor and host defense against Toxoplasma gondii infection
    “...-activated protein kinase and nuclear factor-κB signaling in macrophages. Interestingly, MIF knockdown led...”
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  18. 4498
    Regulation of tumour related genes by dynamic epigenetic alteration at enhancer regions in gastric epithelial cells infected by Epstein-Barr virus
    “... activation and repression. Enhancer dysfunction led to the activation of pathways related to cancer hallmarks...”
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  19. 4499
    Exercise leads to unfavourable cardiac remodelling and enhanced metabolic homeostasis in obese mice with cardiac and skeletal muscle autophagy deficiency
    “... glucose clearance and exercise capacity in lean adult mice. High-fat diet in sedentary mice led...”
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  20. 4500
    Constitutional variants are not associated with HER2-positive breast cancer: results from the SIGNAL/PHARE clinical cohort
    “... any hereditary factors linked to HER2 expression among women with breast cancer. A team in France led...”
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