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  1. 4601
    Development, Interlaboratory Evaluations, and Application of a Simple, High-Throughput <italic toggle="yes">Shigella</italic> Serum Bactericidal Assay
    “... of killing Shigella in a serotype-specific manner. Thus, to facilitate Shigella vaccine development, we have...”
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  2. 4602
    Functionally Related Genes Cluster into Genomic Regions That Coordinate Transcription at a Distance in <named-content content-type="genus-species">Saccharomyces cerevisiae</named-content>
    “... region. The transcription of neighboring genes is correlated in a genome-wide manner, which is a...”
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  3. 4603
    Identification of an Exceptionally Long Intron in the <italic toggle="yes">HAC1</italic> Gene of <italic toggle="yes">Candida parapsilosis</italic>
    “..., suggesting that the UPR was regulated in a different manner. Here we demonstrate that HAC1 plays an important...”
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  4. 4604
    Laboratory Evolution Experiments Help Identify a Predominant Region of Constitutive Stable DNA Replication Initiation
    “... replication during cSDR initiates in a stochastic manner through the length of the chromosome or at specific...”
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  5. 4605
    Preparation, Synergism, and Biocompatibility of in situ Liquid Crystals Loaded with Sinomenine and 5-Fluorouracil for Treatment of Liver Cancer
    por Cao J, Huang J, Gui S, Chu X
    Publicado 2021
    “... in a time- and concentration-dependent manner and had synergistic effects. Further, in vitro release...”
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  6. 4606
    Nanobubbles Containing sPD-1 and Ce6 Mediate Combination Immunotherapy and Suppress Hepatocellular Carcinoma in Mice
    por Tan Y, Yang S, Ma Y, Li J, Xie Q, Liu C, Zhao Y
    Publicado 2021
    “... oscillation, had a stable physical condition, and delivered sPD-1 and Ce6 in a targeted manner. NBs could...”
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  7. 4607
    Eight years of homicide evolution in Monterrey, Mexico: a network approach
    “... of accurate spatio-temporal homicide data results in incomplete descriptions. In order to describe the manner...”
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  8. 4608
    PolyRad – Protection Against Free Radical Damage
    “... and irradiated PolyRad inhibited the viability of HUVEC in a dose-dependent manner. Cell viability of melatonin...”
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  9. 4609
    Challenges in Diabetic Macular Edema Management: An Expert Consensus Report
    “...). Naïve patient was defined, in a strict manner, as a patient who, up to that moment, had never received...”
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  10. 4610
    Differential nanoreprotoxicity of silver nanoparticles in male somatic cells and spermatogonial stem cells
    “... and TM4 cells in a dose- and size-dependent manner by damaging cell membranes and inducing the generation...”
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  11. 4611
    Sustained delivery of a camptothecin prodrug &ndash; CZ48 by nanosuspensions with improved pharmacokinetics and enhanced anticancer activity
    por Dong D, Hsiao CH, Giovanella BC, Wang Y, Chow DSL, Li Z
    Publicado 2019
    “..., respectively.Results: CZ48 released from the nanosuspensions in a sustained manner in contrast to the rapid release...”
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  12. 4612
    Antimycobacterial susceptibility evaluation of rifampicin and isoniazid benz-hydrazone in biodegradable polymeric nanoparticles against Mycobacterium tuberculosis H37Rv strain
    “... in a slow and sustained manner over a period of 1 month and they are more stable in NPs formulation...”
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  13. 4613
    Chitosan gold nanoparticles induce cell death in HeLa and MCF-7 cells through reactive oxygen species production
    “...-AuNPs) exposure.Results: Our data showed that CH-AuNPs are cytotoxic in a dose-dependent manner...”
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  14. 4614
    An extract of the medicinal plant Artemisia annua modulates production of inflammatory markers in activated neutrophils
    “... in a dose-dependent manner. There was complete inhibition by the A. annua extract at 200, 100, and 50...”
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  15. 4615
    Titanium dioxide nanoparticles enhance production of superoxide anion and alter the antioxidant system in human osteoblast cells
    “...- and concentration-dependent manner; (3) ultrastructure changes; (4) decreased SOD and ALP activity; (5) decreased...”
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  16. 4616
    Berberine exerts an anticonvulsant effect and ameliorates memory impairment and oxidative stress in a pilocarpine-induced epilepsy model in&nbsp;the rat
    por Gao F, Gao Y, Liu YF, Wang L, Li YJ
    Publicado 2014
    “... seizure and the time to develop SE in a dose-dependent manner. Malondialdehyde levels were decreased...”
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  17. 4617
    Green synthesis of silver nanoparticles using Ganoderma neo-japonicum Imazeki: a potential cytotoxic agent against breast cancer cells
    “... leakage in a dose-dependent manner. Cells exposed to AgNPs showed increased reactive oxygen species...”
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  18. 4618
    Effect of gold nanoparticles treatment on the testosterone-induced benign prostatic hyperplasia in rats
    “... inhibit the progression of BPH in a size-dependent manner. while 20 nm AuNps ameliorate BPH by its...”
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  19. 4619
    Dimethyl 2,2&prime;-[2,2&prime;-(ethane-1,1-diyl)bis(1H-indole-3,2-diyl)]-diacetate: a small molecule capable of nano-scale assembly, inhibiting venous thrombosis and inducing no bleeding side effect
    por Wang Y, Chen H, Zhang X, Gui L, Wu J, Feng Q, Peng S, Zhao M
    Publicado 2018
    “...-dependent manner. The minimal effective dose of DEBIC was 1.7 &micro;mol/kg. Even the dose of 36 &micro;mol...”
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  20. 4620
    Oxidative stress-mediated antibacterial activity of graphene oxide and reduced graphene oxide in Pseudomonas aeruginosa
    “...-dependent manner. Exposure to GO and rGO induced significant production of superoxide radical anion compared...”
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