Anisotropic forces from spatially constrained focal adhesions mediate contact guidance directed cell migration

por Arja Ray, Oscar Lee, Zaw Win, Rachel M. Edwards, Patrick W. Alford, Deok-Ho Kim, Paolo P. Provenzano
Publicado 2017

A pan-cancer genome-wide analysis reveals tumour dependencies by induction of nonsense-mediated decay

por Zhiyuan Hu, Christopher Yau, Ahmed Ashour Ahmed
Publicado 2017

Lipid-mediated Wnt protein stabilization enables serum-free culture of human organ stem cells

por Nesrin Tüysüz, Louis van Bloois, Stieneke van den Brink, Harry Begthel, Monique M. A. Verstegen, Luis J. Cruz, Lijian Hui, Luc J. W. van der Laan, Jeroen de Jonge, Robert Vries, Eric Braakman, Enrico Mastrobattista, Jan J. Cornelissen, Hans Clevers, Derk ten Berge
Publicado 2017

SHOC2 phosphatase-dependent RAF dimerization mediates resistance to MEK inhibition in RAS-mutant cancers

por Greg G. Jones, Isabel Boned del Río, Sibel Sari, Aysen Sekerim, Lucy C. Young, Nicole Hartig, Itziar Areso Zubiaur, Mona A. El-Bahrawy, Rob E. Hynds, Winnie Lei, Miriam Molina-Arcas, Julian Downward, Pablo Rodriguez-Viciana
Publicado 2019

Lipid analogs reveal features critical for hemolysis and diminish granadaene mediated Group B Streptococcus infection

por Blair Armistead, Pilar Herrero-Foncubierta, Michelle Coleman, Phoenicia Quach, Christopher Whidbey, Jose Justicia, Ruben Tapia, Raquel Casares, Alba Millán, Ali Haidour, Javier Rodriguez Granger, Jay Vornhagen, Verónica Santana-Ufret, Sean Merillat, Kristina Adams Waldorf, Juan Manuel Cuerva, Lakshmi Rajagopal
Publicado 2020

Single AAV-mediated mutation replacement genome editing in limited number of photoreceptors restores vision in mice

por Koji M. Nishiguchi, Kosuke Fujita, Fuyuki Miya, Shota Katayama, Toru Nakazawa
Publicado 2020

Ketohexokinase-A acts as a nuclear protein kinase that mediates fructose-induced metastasis in breast cancer

por Jiyoung Kim, Jengmin Kang, Ye-Lim Kang, Jongmin Woo, Youngsoo Kim, June Huh, Jong-Wan Park
Publicado 2020

The RNA helicase DHX34 functions as a scaffold for SMG1-mediated UPF1 phosphorylation

por Roberto Melero, Nele Hug, Andrés López-Perrote, Akio Yamashita, Javier F. Cáceres, Oscar Llorca
Publicado 2016

The Aryl hydrocarbon receptor mediates tobacco-induced PD-L1 expression and is associated with response to immunotherapy

por Gui-Zhen Wang, Li Zhang, Xin-Chun Zhao, San-Hui Gao, Li-Wei Qu, Hong Yu, Wen-Feng Fang, Yong-Chun Zhou, Fan Liang, Chen Zhang, Yun-Chao Huang, Zhihua Liu, Yang-Xin Fu, Guang-Biao Zhou
Publicado 2019

In vivo proximity proteomics of nascent synapses reveals a novel regulator of cytoskeleton-mediated synaptic maturation

por Erin F. Spence, Shataakshi Dube, Akiyoshi Uezu, Margaret Locke, Erik J. Soderblom, Scott H. Soderling
Publicado 2019

ID3 regulates the MDC1-mediated DNA damage response in order to maintain genome stability

por Jung-Hee Lee, Seon-Joo Park, Gurusamy Hariharasudhan, Min-Ji Kim, Sung Mi Jung, Seo-Yeon Jeong, In-Youb Chang, Cheolhee Kim, Eunae Kim, Jihyeon Yu, Sangsu Bae, Ho Jin You
Publicado 2017

Primary cilia mediate early life programming of adiposity through lysosomal regulation in the developing mouse hypothalamus

por Chan Hee Lee, Do Kyeong Song, Chae Beom Park, Jeewon Choi, Gil Myoung Kang, Sung Hoon Shin, Ijoo Kwon, Soyoung Park, Seongjun Kim, Ji Ye Kim, Hong Dugu, Jae Woo Park, Jong Han Choi, Se Hee Min, Jong-Woo Sohn, Min-Seon Kim
Publicado 2020

Spin-current-mediated rapid magnon localisation and coalescence after ultrafast optical pumping of ferrimagnetic alloys

por E. Iacocca, T.-M. Liu, A. H. Reid, Z. Fu, S. Ruta, P. W. Granitzka, E. Jal, S. Bonetti, A. X. Gray, C. E. Graves, R. Kukreja, Z. Chen, D. J. Higley, T. Chase, L. Le Guyader, K. Hirsch, H. Ohldag, W. F. Schlotter, G. L. Dakovski, G. Coslovich, M. C. Hoffmann, S. Carron, A. Tsukamoto, A. Kirilyuk, A. V. Kimel, Th. Rasing, J. Stöhr, R. F. L. Evans, T. Ostler, R. W. Chantrell, M. A. Hoefer, T. J. Silva, H. A. Dürr
Publicado 2019

Influenza A virus M2 protein triggers mitochondrial DNA-mediated antiviral immune responses

por Miyu Moriyama, Takumi Koshiba, Takeshi Ichinohe
Publicado 2019

Alveolar macrophages are critical for broadly-reactive antibody-mediated protection against influenza A virus in mice

por Wenqian He, Chi-Jene Chen, Caitlin E. Mullarkey, Jennifer R. Hamilton, Christine K. Wong, Paul E. Leon, Melissa B. Uccellini, Veronika Chromikova, Carole Henry, Kevin W. Hoffman, Jean K. Lim, Patrick C. Wilson, Matthew S. Miller, Florian Krammer, Peter Palese, Gene S. Tan
Publicado 2017

Adrenergic-mediated loss of splenic marginal zone B cells contributes to infection susceptibility after stroke

por Laura McCulloch, Craig J. Smith, Barry W. McColl
Publicado 2017

Rapid α-oligomer formation mediated by the Aβ C terminus initiates an amyloid assembly pathway

por Pinaki Misra, Ravindra Kodali, Saketh Chemuru, Karunakar Kar, Ronald Wetzel
Publicado 2016

hCINAP regulates the DNA-damage response and mediates the resistance of acute myelocytic leukemia cells to therapy

por Ruidan Xu, Shuyu Yu, Dan Zhu, Xinping Huang, Yuqi Xu, Yimin Lao, Yonglu Tian, Jinfang Zhang, Zefang Tang, Zemin Zhang, Jing Yi, Hong-Hu Zhu, Xiaofeng Zheng
Publicado 2019

IGF-1 mediated Neurogenesis Involves a Novel RIT1/Akt/Sox2 Cascade

por Sajad Mir, Weikang Cai, Shaun W. Carlson, Kathryn E. Saatman, Douglas A. Andres
Publicado 2017

Intranasal insulin enhances brain functional connectivity mediating the relationship between adiposity and subjective feeling of hunger

por Stephanie Kullmann, Martin Heni, Ralf Veit, Klaus Scheffler, Jürgen Machann, Hans-Ulrich Häring, Andreas Fritsche, Hubert Preissl
Publicado 2017