LSD1-mediated enhancer silencing attenuates retinoic acid signalling during pancreatic endocrine cell development

por Nicholas K. Vinckier, Nisha A. Patel, Ryan J. Geusz, Allen Wang, Jinzhao Wang, Ileana Matta, Austin R. Harrington, Matthew Wortham, Nichole Wetton, Jianxun Wang, Ulupi S. Jhala, Michael G. Rosenfeld, Christopher W. Benner, Hung-Ping Shih, Maike Sander
Publicado 2020

Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription

por Riina Kaukonen, Anja Mai, Maria Georgiadou, Markku Saari, Nicola De Franceschi, Timo Betz, Harri Sihto, Sami Ventelä, Laura Elo, Eija Jokitalo, Jukka Westermarck, Pirkko-Liisa Kellokumpu-Lehtinen, Heikki Joensuu, Reidar Grenman, Johanna Ivaska
Publicado 2016

The impact of alliance justice capability on the performance of strategic alliances in the Indian IT sector: the mediating role of inter-firm commitment

por Mayank Dhaundiyal, Joseph Coughlan
Publicado 2020

Examining the mediating-moderating role of psychological contract breach and abusive supervision on employee well-being in banking sector

por Saba Gulzar, Nadia Ayub, Zuhair Abbas
Publicado 2021

Regulation of CAR T cell-mediated cytokine release syndrome-like toxicity using low molecular weight adapters

por Yong Gu Lee, Haiyan Chu, Yingjuan Lu, Christopher P. Leamon, Madduri Srinivasarao, Karson S. Putt, Philip S. Low
Publicado 2019

CLIC4 regulates apical exocytosis and renal tube luminogenesis through retromer- and actin-mediated endocytic trafficking

por Szu-Yi Chou, Kuo-Shun Hsu, Wataru Otsu, Ya-Chu Hsu, Yun-Cin Luo, Celine Yeh, Syed S. Shehab, Jie Chen, Vincent Shieh, Guo-an He, Michael B. Marean, Diane Felsen, Aihao Ding, Dix P. Poppas, Jen-Zen Chuang, Ching-Hwa Sung
Publicado 2016

Cholesterol and ORP1L-mediated ER contact sites control autophagosome transport and fusion with the endocytic pathway

por Ruud H. Wijdeven, Hans Janssen, Leila Nahidiazar, Lennert Janssen, Kees Jalink, Ilana Berlin, Jacques Neefjes
Publicado 2016

Conserved protein Pir2ARS2 mediates gene repression through cryptic introns in lncRNAs

por Gobi Thillainadesan, Hua Xiao, Sahana Holla, Jothy Dhakshnamoorthy, Lisa M. Miller Jenkins, David Wheeler, Shiv I. S. Grewal
Publicado 2020

An integrated multi-omics approach identifies the landscape of interferon-α-mediated responses of human pancreatic beta cells

por Maikel L. Colli, Mireia Ramos-Rodríguez, Ernesto S. Nakayasu, Maria I. Alvelos, Miguel Lopes, Jessica L. E. Hill, Jean-Valery Turatsinze, Alexandra Coomans de Brachène, Mark A. Russell, Helena Raurell-Vila, Angela Castela, Jonàs Juan-Mateu, Bobbie-Jo M. Webb-Robertson, Lars Krogvold, Knut Dahl-Jorgensen, Lorella Marselli, Piero Marchetti, Sarah J. Richardson, Noel G. Morgan, Thomas O. Metz, Lorenzo Pasquali, Décio L. Eizirik
Publicado 2020

Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death

por Corey Rogers, Teresa Fernandes-Alnemri, Lindsey Mayes, Diana Alnemri, Gino Cingolani, Emad S. Alnemri
Publicado 2017

PIF1 family DNA helicases suppress R-loop mediated genome instability at tRNA genes

por Phong Lan Thao Tran, Thomas J. Pohl, Chi-Fu Chen, Angela Chan, Sebastian Pott, Virginia A. Zakian
Publicado 2017

Abnormal mGluR-mediated synaptic plasticity and autism-like behaviours in Gprasp2 mutant mice

por Mohamed Edfawy, Joana R. Guedes, Marta I. Pereira, Mariana Laranjo, Mário J. Carvalho, Xian Gao, Pedro A. Ferreira, Gladys Caldeira, Lara O. Franco, Dongqing Wang, Ana Luisa Cardoso, Guoping Feng, Ana Luisa Carvalho, João Peça
Publicado 2019

Gray Matter Density of the Dorsomedial Prefrontal Cortex Mediates the Relationship Between Catastrophizing and Anxiety in Somatic Symptom Disorder

por Pan X, Ding W, Sun X, Ji C, Zhou Q, Yan C, Zhou Y, Luo Y
Publicado 2021

Stochastic search and joint fine-mapping increases accuracy and identifies previously unreported associations in immune-mediated diseases

por Jennifer L. Asimit, Daniel B. Rainbow, Mary D. Fortune, Nastasiya F. Grinberg, Linda S. Wicker, Chris Wallace
Publicado 2019

DMRT1-mediated reprogramming drives development of cancer resembling human germ cell tumors with features of totipotency

por Jumpei Taguchi, Hirofumi Shibata, Mio Kabata, Masaki Kato, Kei Fukuda, Akito Tanaka, Sho Ohta, Tomoyo Ukai, Kanae Mitsunaga, Yosuke Yamada, So I Nagaoka, Sho Yamazawa, Kotaro Ohnishi, Knut Woltjen, Tetsuo Ushiku, Manabu Ozawa, Mitinori Saitou, Yoichi Shinkai, Takuya Yamamoto, Yasuhiro Yamada
Publicado 2021

Dissecting the role of H3K27 acetylation and methylation in PRC2 mediated control of cellular identity

por Elisa Lavarone, Caterina M. Barbieri, Diego Pasini
Publicado 2019

An imbalance between specialized pro-resolving lipid mediators and pro-inflammatory leukotrienes promotes instability of atherosclerotic plaques

por Gabrielle Fredman, Jason Hellmann, Jonathan D. Proto, George Kuriakose, Romain A. Colas, Bernhard Dorweiler, E. Sander Connolly, Robert Solomon, David M. Jones, Eric J. Heyer, Matthew Spite, Ira Tabas
Publicado 2016

IL-33 drives group 2 innate lymphoid cell-mediated protection during Clostridium difficile infection

por Alyse L. Frisbee, Mahmoud M. Saleh, Mary K. Young, Jhansi L. Leslie, Morgan E. Simpson, Mayuresh M. Abhyankar, Carrie A. Cowardin, Jennie Z. Ma, Patcharin Pramoonjago, Stephen D. Turner, Alice P. Liou, Erica L. Buonomo, William A. Petri
Publicado 2019

Nrp2 is sufficient to instruct circuit formation of mitral-cells to mediate odour-induced attractive social responses

por Kasumi Inokuchi, Fumiaki Imamura, Haruki Takeuchi, Ryang Kim, Hiroyuki Okuno, Hirofumi Nishizumi, Haruhiko Bito, Takefumi Kikusui, Hitoshi Sakano
Publicado 2017

Amotl1 mediates sequestration of the Hippo effector Yap1 downstream of Fat4 to restrict heart growth

por Chiara V. Ragni, Nicolas Diguet, Jean-François Le Garrec, Marta Novotova, Tatiana P. Resende, Sorin Pop, Nicolas Charon, Laurent Guillemot, Lisa Kitasato, Caroline Badouel, Alexandre Dufour, Jean-Christophe Olivo-Marin, Alain Trouvé, Helen McNeill, Sigolène M Meilhac
Publicado 2017