ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP

por Francesca Bufalieri, Paola Infante, Flavia Bernardi, Miriam Caimano, Paolo Romania, Marta Moretti, Ludovica Lospinoso Severini, Julie Talbot, Ombretta Melaiu, Mirella Tanori, Laura Di Magno, Diana Bellavia, Carlo Capalbo, Stéphanie Puget, Enrico De Smaele, Gianluca Canettieri, Daniele Guardavaccaro, Luca Busino, Angelo Peschiaroli, Simonetta Pazzaglia, Giuseppe Giannini, Gerry Melino, Franco Locatelli, Alberto Gulino, Olivier Ayrault, Doriana Fruci, Lucia Di Marcotullio
Publicado 2019

Human cytomegalovirus evades antibody-mediated immunity through endoplasmic reticulum-associated degradation of the FcRn receptor

por Xiaoyang Liu, Senthilkumar Palaniyandi, Iowis Zhu, Jin Tang, Weizhong Li, Xiaoling Wu, Susan Park Ochsner, C. David Pauza, Jeffrey I. Cohen, Xiaoping Zhu
Publicado 2019

A switch element in the autophagy E2 Atg3 mediates allosteric regulation across the lipidation cascade

por Yumei Zheng, Yu Qiu, Christy R. R. Grace, Xu Liu, Daniel J. Klionsky, Brenda A. Schulman
Publicado 2019

Publisher Correction: ERK-mediated phosphorylation regulates SOX10 sumoylation and targets expression in mutant BRAF melanoma

por Shujun Han, Yibo Ren, Wangxiao He, Huadong Liu, Zhe Zhi, Xinliang Zhu, Tielin Yang, Yu Rong, Bohan Ma, Timothy J. Purwin, Zhenlin Ouyang, Caixia Li, Xun Wang, Xueqiang Wang, Huizi Yang, Yan Zheng, Andrew E. Aplin, Jiankang Liu, Yongping Shao
Publicado 2018

Author Correction: RNA cytosine methylation and methyltransferases mediate chromatin organization and 5-azacytidine response and resistance in leukaemia

por Jason X. Cheng, Li Chen, Yuan Li, Adam Cloe, Ming Yue, Jiangbo Wei, Kenneth A. Watanabe, Jamile M. Shammo, John Anastasi, Qingxi J. Shen, Richard A. Larson, Chuan He, Michelle M. Le Beau, James W. Vardiman
Publicado 2018

A simple new method for aged seed utilization based on melatonin-mediated germination and antioxidant nutrient production

por Song Yu, Xuetian Zhu, Helin Yang, Lihe Yu, Yifei Zhang
Publicado 2021

Enhanced Antitumor Efficacy of Macrophage-Mediated Egg Yolk Lipid-Derived Delivery System Against Breast Cancer

por Lv Y, Jun Y, Tang Z, Li X, Tao M, Zhang Z, Liu L, Sun S, Wang Q, Luo C, Zhang L
Publicado 2020

Improving employees’ performance through internal marketing and organizational learning: Mediating role of organizational innovation in an emerging market

por Saheb Imani, Pantea Foroudi, Nader Seyyedamiri, Niloofar Dehghani
Publicado 2020

CaMKII-mediated Beclin 1 phosphorylation regulates autophagy that promotes degradation of Id and neuroblastoma cell differentiation

por Xuan Li, Xiao-Qi Wu, Rong Deng, Dan-Dan Li, Jun Tang, Wen-Dan Chen, Jing-Hong Chen, Jiao Ji, Lin Jiao, Shan Jiang, Fen Yang, Gong-Kan Feng, Ravichandran Senthilkumar, Fei Yue, Hai-Liang Zhang, Rui-Yan Wu, Yan Yu, Xue-Lian Xu, Jia Mai, Zhi-Ling Li, Xiao-Dan Peng, Yun Huang, Xiang Huang, Ning-Fang Ma, Qian Tao, Yi-Xin Zeng, Xiao-Feng Zhu
Publicado 2017

Adipocyte adaptive immunity mediates diet-induced adipose inflammation and insulin resistance by decreasing adipose Treg cells

por Tuo Deng, Joey Liu, Yanru Deng, Laurie Minze, Xiang Xiao, Valerie Wright, Richeng Yu, Xian C. Li, Alecia Blaszczak, Stephen Bergin, David DiSilvestro, Ryan Judd, David Bradley, Michael Caligiuri, Christopher J. Lyon, Willa A. Hsueh
Publicado 2017

Adipocyte Piezo1 mediates obesogenic adipogenesis through the FGF1/FGFR1 signaling pathway in mice

por ShengPeng Wang, Shuang Cao, Malika Arhatte, Dahui Li, Yue Shi, Sabrina Kurz, Jiong Hu, Lei Wang, Jingchen Shao, Ann Atzberger, Zheng Wang, Changhe Wang, Weijin Zang, Ingrid Fleming, Nina Wettschureck, Eric Honoré, Stefan Offermanns
Publicado 2020

Endothelial E-selectin inhibition improves acute myeloid leukaemia therapy by disrupting vascular niche-mediated chemoresistance

por Valerie Barbier, Johanna Erbani, Corrine Fiveash, Julie M. Davies, Joshua Tay, Michael R. Tallack, Jessica Lowe, John L. Magnani, Diwakar R. Pattabiraman, Andrew C. Perkins, Jessica Lisle, John E. J. Rasko, Jean-Pierre Levesque, Ingrid G. Winkler
Publicado 2020

Cysteine synthases CYSL-1 and CYSL-2 mediate C. elegans heritable adaptation to P. vranovensis infection

por Nicholas O. Burton, Cristian Riccio, Alexandra Dallaire, Jonathan Price, Benjamin Jenkins, Albert Koulman, Eric A. Miska
Publicado 2020

Author Correction: Reactive astrocytes function as phagocytes after brain ischemia via ABCA1-mediated pathway

por Yosuke M. Morizawa, Yuri Hirayama, Nobuhiko Ohno, Shinsuke Shibata, Eiji Shigetomi, Yang Sui, Junichi Nabekura, Koichi Sato, Fumikazu Okajima, Hirohide Takebayashi, Hideyuki Okano, Schuichi Koizumi
Publicado 2017

Exosomes harbor B cell targets in pancreatic adenocarcinoma and exert decoy function against complement-mediated cytotoxicity

por Michela Capello, Jody V. Vykoukal, Hiroyuki Katayama, Leonidas E. Bantis, Hong Wang, Deepali L. Kundnani, Clemente Aguilar-Bonavides, Mitzi Aguilar, Satyendra C. Tripathi, Dilsher S. Dhillon, Amin A. Momin, Haley Peters, Matthew H. Katz, Hector Alvarez, Vincent Bernard, Sammy Ferri-Borgogno, Randall Brand, Douglas G. Adler, Matthew A. Firpo, Sean J. Mulvihill, Jeffrey J. Molldrem, Ziding Feng, Ayumu Taguchi, Anirban Maitra, Samir M. Hanash
Publicado 2019

Development of hRad51–Cas9 nickase fusions that mediate HDR without double-stranded breaks

por Holly A. Rees, Wei-Hsi Yeh, David R. Liu
Publicado 2019

PLK1 facilitates chromosome biorientation by suppressing centromere disintegration driven by BLM-mediated unwinding and spindle pulling

por Owen Addis Jones, Ankana Tiwari, Tomisin Olukoga, Alex Herbert, Kok-Lung Chan
Publicado 2019

Novel Application of Magnetite Nanoparticle-Mediated Vitamin D3 Delivery for Peritoneal Dialysis-Related Peritoneal Damage

por Cheng FY, Chiou YY, Hung SY, Lin TM, Wang HK, Lin CW, Liou HH, Chang MY, Wang HH, Lee YC
Publicado 2021

A reversible phospho-switch mediated by ULK1 regulates the activity of autophagy protease ATG4B

por N. Pengo, A. Agrotis, K. Prak, J. Jones, R. Ketteler
Publicado 2017

Calcium-sensing receptor-mediated NLRP3 inflammasome response to calciprotein particles drives inflammation in rheumatoid arthritis

por Elisabeth Jäger, Supriya Murthy, Caroline Schmidt, Magdalena Hahn, Sarah Strobel, Anna Peters, Claudia Stäubert, Pelin Sungur, Tom Venus, Mandy Geisler, Veselina Radusheva, Stefanie Raps, Kathrin Rothe, Roger Scholz, Sebastian Jung, Sylke Wagner, Matthias Pierer, Olga Seifert, Wenhan Chang, Irina Estrela-Lopis, Nora Raulien, Knut Krohn, Norbert Sträter, Stephanie Hoeppener, Torsten Schöneberg, Manuela Rossol, Ulf Wagner
Publicado 2020