Insertion-sequence-mediated mutations both promote and constrain evolvability during a long-term experiment with bacteria

por Jessika Consuegra, Joël Gaffé, Richard E. Lenski, Thomas Hindré, Jeffrey E. Barrick, Olivier Tenaillon, Dominique Schneider
Publicado 2021

Erratum: Revealing the mechanism of passive transport in lipid bilayers via phonon-mediated nanometre-scale density fluctuations

por Mikhail Zhernenkov, Dima Bolmatov, Dmitry Soloviov, Kirill Zhernenkov, Boris P. Toperverg, Alessandro Cunsolo, Alexey Bosak, Yong Q. Cai
Publicado 2016

CDK2-mediated site-specific phosphorylation of EZH2 drives and maintains triple-negative breast cancer

por Lei Nie, Yongkun Wei, Fei Zhang, Yi-Hsin Hsu, Li-Chuan Chan, Weiya Xia, Baozhen Ke, Cihui Zhu, Rong Deng, Jun Tang, Jun Yao, Yu-Yi Chu, Xixi Zhao, Ye Han, Junwei Hou, Longfei Huo, How-Wen Ko, Wan-Chi Lin, Hirohito Yamaguchi, Jung-Mao Hsu, Yi Yang, Dean N. Pan, Jennifer L. Hsu, Celina G. Kleer, Nancy E. Davidson, Gabriel N. Hortobagyi, Mien-Chie Hung
Publicado 2019

Akt and STAT5 mediate naïve human CD4+ T-cell early metabolic response to TCR stimulation

por Nicholas Jones, Emma E. Vincent, James G. Cronin, Silvia Panetti, Megan Chambers, Sean R. Holm, Sian E. Owens, Nigel J. Francis, David K. Finlay, Catherine A. Thornton
Publicado 2019

DNase II mediates a parthanatos-like developmental cell death pathway in Drosophila primordial germ cells

por Lama Tarayrah-Ibraheim, Elital Chass Maurice, Guy Hadary, Sharon Ben-Hur, Alina Kolpakova, Tslil Braun, Yoav Peleg, Keren Yacobi-Sharon, Eli Arama
Publicado 2021

Predictive value of brachial artery flow-mediated dilation on coronary artery abnormality in acute stage of Kawasaki disease

por Yizhou Wen, Xianmin Wang, Yonghong Guo, Mei Jin, Jimei Xi, Tingting Chen, Kun Shi, Yaheng Lu
Publicado 2021

Islr regulates canonical Wnt signaling-mediated skeletal muscle regeneration by stabilizing Dishevelled-2 and preventing autophagy

por Kuo Zhang, Yuying Zhang, Lijie Gu, Miaomiao Lan, Chuncheng Liu, Meng Wang, Yang Su, Mengxu Ge, Tongtong Wang, Yingying Yu, Chang Liu, Lei Li, Qiuyan Li, Yaofeng Zhao, Zhengquan Yu, Fudi Wang, Ning Li, Qingyong Meng
Publicado 2018

CRISPR/Cas9-mediated glycolate oxidase disruption is an efficacious and safe treatment for primary hyperoxaluria type I

por Nerea Zabaleta, Miren Barberia, Cristina Martin-Higueras, Natalia Zapata-Linares, Isabel Betancor, Saray Rodriguez, Rebeca Martinez-Turrillas, Laura Torella, Africa Vales, Cristina Olagüe, Amaia Vilas-Zornoza, Laura Castro-Labrador, David Lara-Astiaso, Felipe Prosper, Eduardo Salido, Gloria Gonzalez-Aseguinolaza, Juan R. Rodriguez-Madoz
Publicado 2018

Surface chemistry-mediated modulation of adsorbed albumin folding state specifies nanocarrier clearance by distinct macrophage subsets

por Michael P. Vincent, Sharan Bobbala, Nicholas B. Karabin, Molly Frey, Yugang Liu, Justin O. Navidzadeh, Trevor Stack, Evan A. Scott
Publicado 2021

MLL5 suppresses antiviral innate immune response by facilitating STUB1-mediated RIG-I degradation

por Peipei Zhou, Xiaodan Ding, Xiaoling Wan, Lulu Liu, Xiujie Yuan, Wei Zhang, Xinhui Hui, Guangxun Meng, Hui Xiao, Bin Li, Jin Zhong, Fajian Hou, Lihwen Deng, Yan Zhang
Publicado 2018

De novo histidine biosynthesis protects Mycobacterium tuberculosis from host IFN-γ mediated histidine starvation

por Abhisek Dwivedy, Anam Ashraf, Bhavya Jha, Deepak Kumar, Nisheeth Agarwal, Bichitra K. Biswal
Publicado 2021

UCHL1-HIF-1 axis-mediated antioxidant property of cancer cells as a therapeutic target for radiosensitization

por Ryota Nakashima, Yoko Goto, Sho Koyasu, Minoru Kobayashi, Akiyo Morinibu, Michio Yoshimura, Masahiro Hiraoka, Ester M. Hammond, Hiroshi Harada
Publicado 2017

Hydrolysis of Hyaluronic Acid in Lymphedematous Tissue Alleviates Fibrogenesis via TH1 Cell-Mediated Cytokine Expression

por Sungrae Cho, Kangsan Roh, Jaehyun Park, Yong Seok Park, Minji Lee, Seungchan Cho, Eui-Joon Kil, Mun-Ju Cho, Jeong Su Oh, Hee-Seong Byun, Sang-Ho Cho, Kyewon Park, Hee Kang, Jinmo Koo, Chang-Hwan Yeom, Sukchan Lee
Publicado 2017

Small molecule-mediated tribbles homolog 3 promotes bone formation induced by bone morphogenetic protein-2

por Jiabing Fan, Joan Pi-Anfruns, Mian Guo, Dan C. S. Im, Zhong-Kai Cui, Soyon Kim, Benjamin M. Wu, Tara L. Aghaloo, Min Lee
Publicado 2017

Schisandrin B reverses doxorubicin resistance through inhibiting P-glycoprotein and promoting proteasome-mediated degradation of survivin

por Shengpeng Wang, Anqi Wang, Min Shao, Ligen Lin, Peng Li, Yitao Wang
Publicado 2017

Directional cell expansion requires NIMA-related kinase 6 (NEK6)-mediated cortical microtubule destabilization

por Shogo Takatani, Shinichiro Ozawa, Noriyoshi Yagi, Takashi Hotta, Takashi Hashimoto, Yuichiro Takahashi, Taku Takahashi, Hiroyasu Motose
Publicado 2017

Differential sensitivity to infections and antimicrobial peptide-mediated immune response in four silkworm strains with different geographical origin

por Ottavia Romoli, Alessio Saviane, Andrea Bozzato, Paola D’Antona, Gianluca Tettamanti, Andrea Squartini, Silvia Cappellozza, Federica Sandrelli
Publicado 2017

Relationship between obesity and development of erosive reflux disease: A mediation analysis of the role of cardiometabolic risk factors

por Hyuk Lee, Yaeji Lim, Sangah Chi, Yang Won Min, Byung-Hoon Min, Jun Haeng Lee, Poong-Lyul Rhee, Jae J. Kim
Publicado 2017

SMYD3 Promotes Homologous Recombination via Regulation of H3K4-mediated Gene Expression

por Yun-Ju Chen, Cheng-Hui Tsai, Pin-Yu Wang, Shu-Chun Teng
Publicado 2017

FTO-mediated cytoplasmic m6Am demethylation adjusts stem-like properties in colorectal cancer cell

por Sébastien Relier, Julie Ripoll, Hélène Guillorit, Amandine Amalric, Cyrinne Achour, Florence Boissière, Jérôme Vialaret, Aurore Attina, Françoise Debart, Armelle Choquet, Françoise Macari, Virginie Marchand, Yuri Motorin, Emmanuelle Samalin, Jean-Jacques Vasseur, Julie Pannequin, Francesca Aguilo, Evelyne Lopez-Crapez, Christophe Hirtz, Eric Rivals, Amandine Bastide, Alexandre David
Publicado 2021