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  1. 3901
    EZH2 Inhibition Compromises α4-1BB-Mediated Antitumor Efficacy by Reducing the Survival and Effector Programming of CD8+ T Cells
    “... treatment. These data support the requirement of EZH2 function in 4-1BB-mediated CD8+ T cell expansion...”
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  2. 3902
    Inhibition of FOXO3 tumor suppressor function by betaTrCP1 through ubiquitin-mediated degradation in a tumor mouse model.
    “... to elucidate the molecular mechanisms underlying the ubiquitin-mediated degradation of FOXO3 tumor suppressor...”
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  3. 3903
    Ganoderic Acid A-Mediated Modulation of Microglial Polarization is Involved in Depressive-Like Behaviors and Neuroinflammation in a Rat Model of Post-Stroke Depression
    por Zhang L, Zhang L, Sui R
    Publicado 2021
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  4. 3904
    SMARCA4/2 loss inhibits chemotherapy-induced apoptosis by restricting IP3R3-mediated Ca2+ flux to mitochondria
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  5. 3905
    A standardized extract of Asparagus officinalis stem improves HSP70-mediated redox balance and cell functions in bovine cumulus-granulosa cells
    “...-mediated redox balance and cell function in bovine CG cells....”
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  6. 3906
    Integrin-αV-mediated activation of TGF-β regulates anti-tumour CD8 T cell immunity and response to PD-1 blockade
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  7. 3907
    Selected Immunological Mediators and Cervical Microbial Signatures in Women with <named-content content-type="genus-species">Chlamydia trachomatis</named-content> Infection
    “... the levels of selected immune mediators and the community state types of the cervical microbiota in C...”
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  8. 3908
    Gamma irradiation-mediated inactivation of enveloped viruses with conservation of genome integrity: Potential application for SARS-CoV-2 inactivated vaccine development
    por Abolaban Fouad A., Djouider Fathi M.
    Publicado 2021
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  9. 3909
    pERK-mediated IL8 secretion can enhance the migration, invasion, and cisplatin resistance of CD10-positive oral cancer cells
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  10. 3910
    Impact of sex on use of low tidal volume ventilation in invasively ventilated ICU patients-A mediation analysis using two observational cohorts.
    “...), was the primary outcome. Mediation analysis, a method to dissect total effect into direct and indirect effects...”
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  11. 3911
    Cross-sectional study of approaches to diagnosis and management of dogs with immune-mediated haemolytic anaemia in primary care and referral veterinary practices in the United Kingdom.
    “...-certified clinicians (BCCs) approach treatment of dogs with immune-mediated haemolytic anaemia (IMHA...”
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  12. 3912
    Emerging Transcriptional and Genomic Mechanisms Mediating Carbapenem and Polymyxin Resistance in <italic toggle="yes">Enterobacteriaceae</italic>: a Systematic Review of Current Reports
    “... describes the current coding and noncoding genetic and transcriptional mechanisms mediating carbapenem...”
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  13. 3913
    Understanding the Mediating Role of Anxiety and Depression on the Relationship Between Perceived Stress and Sleep Quality Among Health Care Workers in the COVID-19 Response
    por Luo Y, Fei S, Gong B, Sun T, Meng R
    Publicado 2021
    “... study was to explore the role of anxiety and depression as a potential mediator between perceived stress...”
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  14. 3914
    ATR/Chk1 signaling induces autophagy through sumoylated RhoB-mediated lysosomal translocation of TSC2 after DNA damage
    “... signaling-induced autophagy in response to DNA damage, through an ATR/Chk1/RhoB-mediated lysosomal...”
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  15. 3915
    HOXA9 inhibits HIF-1α-mediated glycolysis through interacting with CRIP2 to repress cutaneous squamous cell carcinoma development
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  16. 3916
    Publisher Correction: Leishmania RNA virus exacerbates Leishmaniasis by subverting innate immunity via TLR3-mediated NLRP3 inflammasome inhibition
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  17. 3917
    Author Correction: Regulation of T cell afferent lymphatic migration by targeting LTβR-mediated non-classical NFκB signaling
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  18. 3918
    RNA surveillance via nonsense-mediated mRNA decay is crucial for longevity in daf-2/insulin/IGF-1 mutant C. elegans
    “.... report that nonsense-mediated mRNA decay, a RNA quality control mechanism, is enhanced in long-lived daf...”
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  19. 3919
    Enrichment of hydroxylated C24- and C26-acyl-chain sphingolipids mediates PIN2 apical sorting at trans-Golgi network subdomains
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  20. 3920
    The Polycomb protein Ezl1 mediates H3K9 and H3K27 methylation to repress transposable elements in Paramecium
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