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  1. 3941
    Caveolae-mediated Tie2 signaling contributes to CCM pathogenesis in a brain endothelial cell-specific Pdcd10-deficient mouse model
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  2. 3942
    Amylose starch with no detectable branching developed through DNA-free CRISPR-Cas9 mediated mutagenesis of two starch branching enzymes in potato
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  3. 3943
    Mediating Speech Actions of an Adult in Telling a Story by a Child: Hypothesis about the Interactive Nature of Narration in a Child’s Speech Activity
    por N. M. Yurieva
    Publicado 2020
    “... of the influence of an adult on a child’s telling a story, to highlight different forms of mediating actions...”
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  4. 3944
    Down-regulation of EPB41L4A-AS1 mediated the brain aging and neurodegenerative diseases via damaging synthesis of NAD+ and ATP
    “... downregulation-mediated decrease of NAD+ and ATP synthesis. Our results provide new perspectives...”
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  5. 3945
    c-Jun amino-terminal kinase-1 mediates glucose-responsive upregulation of the RNA editing enzyme ADAR2 in pancreatic beta-cells.
    “... islets, the stress-activated protein kinase JNK1 mediates the upregulation of ADAR2 in response...”
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  6. 3946
    Leptospiral hemolysins induce proinflammatory cytokines through Toll-like receptor 2-and 4-mediated JNK and NF-κB signaling pathways.
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  7. 3947
    A PXR-mediated negative feedback loop attenuates the expression of CYP3A in response to the PXR agonist pregnenalone-16α-carbonitrile.
    “... into the regulation of the PXR-mediated regulatory signal networks provides a potential mechanistic rationale...”
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  8. 3948
    2-Deoxy-D-glucose treatment of endothelial cells induces autophagy by reactive oxygen species-mediated activation of the AMP-activated protein kinase.
    “...-mediated knockdown of AMPK. Finally, pretreatment of BAEC with 2-DG increased endothelial cell viability...”
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  9. 3949
    Docosahexaenoic acid-derived neuroprotectin D1 induces neuronal survival via secretase- and PPARγ-mediated mechanisms in Alzheimer's disease models.
    “...Neuroprotectin D1 (NPD1) is a stereoselective mediator derived from the omega-3 essential fatty...”
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  10. 3950
    Nonsense-mediated mRNA decay and loss-of-function of the protein underlie the X-linked epilepsy associated with the W356× mutation in synapsin I.
    “...-mediated mRNA decay (NMD). Given that the NMD efficiency is highly variable among individuals and cell...”
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  11. 3951
    Cytochrome P450 3A1 mediates 2,2',4,4'-tetrabromodiphenyl ether-induced reduction of spermatogenesis in adult rats.
    “... of attention. However, it is unclear whether CYP-mediated metabolism contributes to BDE47-induced reproductive...”
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  12. 3952
    I-SceI-mediated double-strand break does not increase the frequency of homologous recombination at the Dct locus in mouse embryonic stem cells.
    “... targeting was not improved by the DSB induction, indicating a limited capacity of I-SceI to mediate...”
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  13. 3953
    C-terminal clipping of chemokine CCL1/I-309 enhances CCR8-mediated intracellular calcium release and anti-apoptotic activity.
    “.... This is corroborated by CPM-mediated trimming and modulation of inflammatory factors, and expression of the protease...”
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  14. 3954
    Migration of Th1 lymphocytes is regulated by CD152 (CTLA-4)-mediated signaling via PI3 kinase-dependent Akt activation.
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  15. 3955
    Lung transplant after 6 months on ECMO support for SARS-CoV-2-induced ARDS complicated by severe antibody-mediated rejection
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  16. 3956
    Rapid Detection of Wheat Blast Pathogen Magnaporthe oryzae Triticum Pathotype Using Genome-Specific Primers and Cas12a-mediated Technology
    “... established a loop-mediated isothermal amplification (LAMP) method to detect MoT at isothermal conditions...”
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  17. 3957
    An Efficient, Rapid, and Recyclable System for CRISPR-Mediated Genome Editing in <named-content content-type="genus-species">Candida albicans</named-content>
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  18. 3958
    Activation of ERK and p38 Reduces AZD8055-Mediated Inhibition of Protein Synthesis in Hepatocellular Carcinoma HepG2 Cell Line
    “... enhance the efficacy of AZD8055-mediated inhibition of protein synthesis. In addition, AZD8055 down...”
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  19. 3959
    Fatty Acids Inhibit LAMP2-Mediated Autophagy Flux via Activating ER Stress Pathway in Alcohol-Related Liver DiseaseSummary
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  20. 3960
    Nicotinic Acetylcholine Receptor Subunit α7 Mediates Cigarette Smoke-Induced PD-L1 Expression in Human Bronchial Epithelial Cells
    “... be diminished by treatment with <i>CHRNA7</i> small-interfering RNA, and the relevant signaling was mediated via...”
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