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  1. 4421
    Novel Tl(III) complexes containing pyridine-2,6-dicarboxylate derivatives with selective anticancer activity through inducing mitochondria-mediated apoptosis in A375 cells
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  2. 4422
    PMO-based let-7c site blocking oligonucleotide (SBO) mediated utrophin upregulation in mdx mice, a therapeutic approach for Duchenne muscular dystrophy (DMD)
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  3. 4423
    Annexin A1 down-regulation in head and neck squamous cell carcinoma is mediated via transcriptional control with direct involvement of miR-196a/b
    “... contributed to identify key regions and potential mediators of ANXA1 transcriptional control. This study...”
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  4. 4424
    miR-129-3p Targeting of MCU Protects Against Glucose Fluctuation-Mediated Neuronal Damage via a Mitochondrial-Dependent Intrinsic Apoptotic Pathway
    por Wang B, Li Y, You C
    Publicado 2021
    “... effects of miR-129-3p targeting mitochondrial calcium uniporter (MCU) in glucose fluctuation-mediated...”
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  5. 4425
    MicroRNA 1228 Mediates the Viability of High Glucose-Cultured Renal Tubule Cells through Targeting Thrombospondin 2 and PI3K/AKT Signaling Pathway
    por Taoran Mo, Qiang Fu, Xiaoyang Hu, Yin Fu, Ji Li
    Publicado 2021
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  6. 4426
    Mufangji Decoction and Its Active Ingredient Patchouli Alcohol Inhibit Tumor Growth through Regulating Akt/mTOR-Mediated Autophagy in Nonsmall-Cell Lung Cancer
    “... is related to the induction of Akt/mTOR signaling pathway-mediated autophagy in NSCLC cells. Conclusion...”
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  7. 4427
    Anti-metastatic effect of GV1001 on prostate cancer cells; roles of GnRHR-mediated Gαs-cAMP pathway and AR-YAP1 axis
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  8. 4428
    Quercetin inhibits angiogenesis mediated human prostate tumor growth by targeting VEGFR- 2 regulated AKT/mTOR/P70S6K signaling pathways.
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  9. 4429
    <named-content content-type="genus-species">Toxoplasma gondii</named-content> MAF1b Binds the Host Cell MIB Complex To Mediate Mitochondrial Association
    “..., but the identities of the partners that mediate this interaction have not previously been described in any infection...”
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  10. 4430
    Harmine Hydrochloride Mediates the Induction of G2/M Cell Cycle Arrest in Breast Cancer Cells by Regulating the MAPKs and AKT/FOXO3a Signaling Pathways
    por Chae Won Ock, Gi Dae Kim
    Publicado 2021
    “... that mitogen-activated protein kinases (MAPKs) and AKT/FOXO3a signaling pathways mediate the induction of cell...”
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  11. 4431
    Cationic Antheraea pernyi Silk Fibroin-Modified Adenovirus-Mediated ING4 and IL-24 Dual Gene Coexpression Vector Suppresses the Growth of Hepatoma Carcinoma Cells
    por Qu J, Wang W, Feng Y, Niu L, Li M, Yang J, Xie Y
    Publicado 2019
    “... efficiency than the naked Ad. The CASF/Ad complex could effectively mediate the expression of the target gene...”
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  12. 4432
    Insulin-like Growth Factor Binding Protein-2 (IGFBP2) Is a Key Molecule in the MACC1-Mediated Platelet Communication and Metastasis of Colorectal Cancer Cells
    “... (CRC) and other solid tumor entities, mediating motility and metastasis, making MACC1 an accepted...”
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  13. 4433
    Ablation of Red Stable Transfected Claudin Expressing Canine Prostate Adenocarcinoma and Transitional Cell Carcinoma Cell Lines by C-CPE Gold-Nanoparticle-Mediated Laser Intervention
    “...-nanoparticle-mediated laser perforation (GNOME-LP). A PAC and TCC cell lines, as well as red fluorescence...”
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  14. 4434
    CD40 Pathway and IL-2 Expression Mediate the Differential Outcome of Colorectal Cancer Patients with Different <i>CSF1R</i> c.1085 Genotypes
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  15. 4435
    RASSF1A-Mediated Suppression of Estrogen Receptor Alpha (ERα)-Driven Breast Cancer Cell Growth Depends on the Hippo-Kinases LATS1 and 2
    “... that keeps ERα expression and function under control. We observed that RASSF1A mediates the suppression of ER...”
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  16. 4436
    Development of a Multiplex Loop-Mediated Isothermal Amplification Assay for Diagnosis of <i>Plasmodium</i> spp., <i>Plasmodium falciparum</i> and <i>Plasmodium vivax</i>
    “... developed a multiplex malaria Pan/Pf/Pv/actin beta loop-mediated isothermal amplification (LAMP) to diagnose...”
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  17. 4437
    Methyl ferulic acid ameliorates alcohol-induced hepatic insulin resistance via miR-378b-mediated activation of PI3K-AKT pathway
    “... and illuminate the function of miR-378b-mediated phosphoinositide 3-kinase (PI3K)/protein kinase B (AKT) pathway...”
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  18. 4438
    Aerobic fitness mediates the intervention effects of a school-based physical activity intervention on academic performance. The school in Motion study – A cluster randomized controlled trial
    “... performance were mediated by aerobic fitness. The School in Motion study was a nine-month cluster randomized...”
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  19. 4439
    First Global Report of Plasmid-Mediated <i>mcr-1</i> and Extended-Spectrum Beta-Lactamase-Producing <i>Escherichia coli</i> from Sheep in Portugal
    “... <i>E. coli</i> was concomitantly colistin-resistant and presented the plasmid-mediated <i>mcr-1</i...”
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  20. 4440
    <italic toggle="yes">Bacteroidales</italic> Secreted Antimicrobial Proteins Target Surface Molecules Necessary for Gut Colonization and Mediate Competition <italic toggle="yes">In Vivo</italic>
    “... microbial community. Interference competition, mediated by bacterial factors that directly harm other...”
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