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  1. 5241
    Natural killer cell function, an important target for infection and tumor protection, is impaired in type 2 diabetes.
    “... cell defects. We demonstrated that endoplasmic reticulum (ER) stress, an important mediator in diabetes...”
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  2. 5242
    ROLE OF TUMOR NECROSIS FACTOR ALPHA IN IMMUNE PATHOGENESIS OF DIFFERENT DISEASES AND ITS SIGNIFICANCE FOR EVOLVING ANTICYTOKINE THERAPY WITH MONOCLONAL ANTIBODIES
    “..., and on the other hand, acts as mediator of inflammatory processes in various human diseases. Intensive...”
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  3. 5243
    Transforming growth factor β1 induces the expression of collagen type I by DNA methylation in cardiac fibroblasts.
    “...Transforming growth factor-beta (TGF-β), a key mediator of cardiac fibroblast activation, has a...”
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  4. 5244
    PLASMA Th1/Th2/Th17 CYTOKINE PROFILE AND CYTOKINE GENE POLYMORPHISMS (IL12B, IL13, IL31, IL33) IN ASTHMATIC CHILDREN: A MAGNETIC MULTIPLEX ASSAY
    “... disability. Since BA is a genetically mediated process, the severity of the disease is assumed to depend...”
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  5. 5245
    MiR-152 influences osteoporosis through regulation of osteoblast differentiation by targeting RICTOR
    por Li Feng, Bo Xia, Bao-Fang Tian, Gong-Biao Lu
    Publicado 2019
    “... and alleviated osteoporosis by up-regulating RICTOR. Therefore, miR-152 may be an essential mediator...”
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  6. 5246
    Loss of Endothelial Hypoxia Inducible Factor‐Prolyl Hydroxylase 2 Induces Cardiac Hypertrophy and Fibrosis
    “.... Methods and Results Mice with Egln1Tie2Cre (Tie2‐Cre‐mediated deletion of Egln1 [encoding PHD2]) exhibited...”
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  7. 5247
    Two Accessory Proteins Govern MmpL3 Mycolic Acid Transport in Mycobacteria
    “... component of the cell wall, a target of mycobacterium-specific antibiotics and a mediator of Mycobacterium...”
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  8. 5248
    Hematocrit and the risk of recurrent venous thrombosis: a prospective cohort study.
    “... dropped by 23.5% after adjustment for hematocrit. Hematocrit was not a significant mediator of the sex...”
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  9. 5249
    Anti-arthritic effects of magnolol in human interleukin 1β-stimulated fibroblast-like synoviocytes and in a rat arthritis model.
    “...). The expression of these mediators is controlled at the transcriptional level. The purposes of this study were...”
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  10. 5250
    In vivo near-infrared imaging of fibrin deposition in thromboembolic stroke in mice.
    “... imaging provides in vivo imaging of activated factor XIII (FXIIIa), an important mediator of thrombosis...”
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  11. 5251
    Thioredoxin from the Indianmeal moth Plodia interpunctella: cloning and test of the allergenic potential in mice.
    “... production, mediator release from RBL cells, T-cell proliferation and cytokine production were measured.<h4...”
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  12. 5252
    Estrogen-induced nongenomic calcium signaling inhibits lipopolysaccharide-stimulated tumor necrosis factor α production in macrophages.
    “... 30 (GPR30) was suggested to be a membrane estrogen receptor (mER) that can mediate nongenomic...”
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  13. 5253
    FOXA1 and adaptive response determinants to HER2 targeted therapy in TBCRC 036
    “... implicated the pioneer transcription factor FOXA1 as a mediator of adaptive responses. Lapatinib...”
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  14. 5254
    Alpha lipoic acid attenuates ER stress and improves glucose uptake through DNAJB3 cochaperone
    “... the tunicamycin-mediated transcriptional activation of ATF6 while it enhanced the insulin-stimulated glucose...”
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  15. 5255
    Attenuation of the macrophage inflammatory activity by TiO2 nanotubes via inhibition of MAPK and NF-&kappa;B pathways
    por Neacsu P, Mazare A, Schmuki P, Cimpean A
    Publicado 2015
    “... the activation of macrophages in inflammatory events, promoting the transcription of pro-inflammatory mediator...”
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  16. 5256
    Tcf1 Sustains the Expression of Multiple Regulators in Promoting Early Natural Killer Cell Development
    “...T cell factor 1 (Tcf1) is known as a critical mediator for natural killer (NK) cell development...”
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  17. 5257
    Interaction of social role functioning and coping in people with recent-onset attenuated psychotic symptoms: a case study of three Chinese women at clinical high risk for psychosis
    “... activities may be a risk factor in the development of psychosis and a mediator of functional sequelae...”
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  18. 5258
    Effect of pulsed electromagnetic field treatment on programmed resolution of inflammation pathway markers in human cells in culture
    por Kubat NJ, Moffett J, Fray LM
    Publicado 2015
    “... in lipid mediator biosynthesis was also observed, including an increase in arachidonate 12- and 15...”
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  19. 5259
    Oxidative Stress Caused by Ozone Exposure Induces Changes in P2X7 Receptors, Neuroinflammation, and Neurodegeneration in the Rat Hippocampus
    “.... Adenosine 5′triphosphate (ATP) can act as a mediator in intercellular communication between neurons...”
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  20. 5260
    Identification of a novel bacterial outer membrane interleukin-1Β-binding protein from Aggregatibacter actinomycetemcomitans.
    “..., and the diseased sites of the periodontium exhibit increased levels of the proinflammatory mediator interleukin (IL...”
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