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  1. 5261
    The heme oxygenase-1 inducer THI-56 negatively regulates iNOS expression and HMGB1 release in LPS-activated RAW 264.7 cells and CLP-induced septic mice.
    “... to act as a late mediator of septic shock. The effect of ((S)-6,7-dihydroxy-1-(4-hydroxynaphthylmethyl...”
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  2. 5262
    Osteopontin and systemic lupus erythematosus association: a probable gene-gender interaction.
    “...Osteopontin (SPP1) is an important bone matrix mediator found to have key roles in inflammation...”
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  3. 5263
    Knock out of S1P3 receptor signaling attenuates inflammation and fibrosis in bleomycin-induced lung injury mice model.
    “... inflammatory mediator of the pathogenesis of airway inflammation, but the role of S1P3 in the pathogenesis...”
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  4. 5264
    The acute satellite cell response and skeletal muscle hypertrophy following resistance training.
    “..., we focused on the myogenic stem cell population, the satellite cell (SC) as a potential mediator...”
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  5. 5265
    An immunological marker of tolerance to infection in wild rodents.
    “... of the transcription factor Gata3 (a mediator of Th2 immunity) as an immunological biomarker of this tolerance response...”
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  6. 5266
    Stress and self-efficacy as specific predictors of safety at work in the aviation sector
    “... carried out, including regression analyses and a model of analysis of mediation between variables, have...”
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  7. 5267
    Differentially expressed wound healing-related microRNAs in the human diabetic cornea.
    “... be an important mediator of abnormal wound healing....”
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  8. 5268
    Fibroblast growth factor 21 associating with serotonin and dopamine in the cerebrospinal fluid predicts impulsivity in healthy subjects
    “... the association between cerebrospinal fluid (CSF) fibroblast growth factor 21 (FGF21), a key hormonal mediator...”
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  9. 5269
    Circulating miR-146a as a possible candidate biomarker in the indeterminate phase of Chagas disease
    “... family member 5 was downregulated in both phases. This gene serves as a mediator in the TGF-&#946...”
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  10. 5270
    UHRF1 Suppresses HIV-1 Transcription and Promotes HIV-1 Latency by Competing with p-TEFb for Ubiquitination-Proteasomal Degradation of Tat
    “... motifs of HIV-1 Tat via its TTD, PHD, and RING finger domains. Furthermore, UHRF1 mediated K48-linked...”
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  11. 5271
    PERK signaling through C/EBPδ contributes to ER stress-induced expression of immunomodulatory and tumor promoting chemokines by cancer cells
    “... the transcription factor C/EBPδ (CEBPD) as a mediator of PERK signaling to secretion of tumor promoting chemokines...”
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  12. 5272
    Bcl-2 regulates HIF-1alpha protein stabilization in hypoxic melanoma cells via the molecular chaperone HSP90.
    “... mediator of the cellular response to hypoxia. Enhanced levels of HIF-1alpha, the oxygen-regulated subunit...”
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  13. 5273
    Anti-inflammatory activity of lefamulin versus azithromycin and dexamethasone in vivo and in vitro in a lipopolysaccharide-induced lung neutrophilia mouse model.
    “... and inflammatory mediator induction in lung homogenates were measured 4h postchallenge. Single subcutaneous...”
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  14. 5274
    Total Lipopolysaccharide from the Human Gut Microbiome Silences Toll-Like Receptor Signaling
    “... immune signaling and an important mediator of the microbiome’s influence on host physiology...”
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  15. 5275
    Overview on the Discovery and Development of Anti-Inflammatory Drugs: Should the Focus Be on Synthesis or Degradation of PGE2?
    por Mahesh G, Anil Kumar K, Reddanna P
    Publicado 2021
    “... of the Pharma companies. As PGE2 is the key mediator of inflammatory disorders, coming up with a strategy...”
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  16. 5276
    Influence of Childhood Maltreatment, Adulthood Stressful Life Events, and Affective Temperaments on Premenstrual Mental Symptoms of Nonclinical Adult Volunteers
    “... study suggest that affective temperament is a mediator of the influence of childhood maltreatment on PMM...”
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  17. 5277
    Self-management behavior and fasting plasma glucose control in patients with type 2 diabetes mellitus over 60 years old: multiple effects of social support on quality of life
    “... support, self-management behavior, FPG level, and quality of life were noted. A multiple mediator model...”
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  18. 5278
    Negative regulation of NF-κB by the ING4 tumor suppressor in breast cancer.
    “...Nuclear Factor kappa B (NF-κB) is a key mediator of normal immune response but contributes...”
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  19. 5279
    IMMUNOTHERAPY EFFICIENCY IN RHINOSINUSITIS PATIENTS
    por I. V. Stagnieva, A. S. Simbirtsev
    Publicado 2015
    “... in pathogenesis of the disease latency. Substance P seems to be a universal mediator of painful irritation...”
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  20. 5280
    SYK-3BP2 Pathway Activity in Parenchymal and Myeloid Cells Is a Key Pathogenic Factor in Metabolic SteatohepatitisSummary
    “... deficiency and SYK deletion in myeloid cells mediated the same protective effects on liver inflammation...”
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