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  1. 6081
    Physiological and proteomic analyses reveal cAMP‐regulated key factors in maize root tolerance to heat stress
    “...‐mediated thermotolerance in root remains unclear. This study was designed to investigate cAMP roles...”
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  2. 6082
    ORBIT: a New Paradigm for Genetic Engineering of Mycobacterial Chromosomes
    “... recombination mediated by the phage Che9c RecT annealase. This oligonucleotide contains a site-specific...”
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  3. 6083
    Whole-Animal Chemical Screen Identifies Colistin as a New Immunomodulator That Targets Conserved Pathways
    por Yun Cai, Xiou Cao, Alejandro Aballay
    Publicado 2014
    “... effective against antibiotic-resistant bacteria. Immune activation by colistin is mediated not only by the p...”
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  4. 6084
    Alterations in Cholesterol Metabolism Restrict HIV-1 <italic toggle="yes">Trans</italic> Infection in Nonprogressors
    “...-presenting cells (APC), i.e., dendritic cells (DC) and B lymphocytes, from NP lacked the ability to mediate...”
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  5. 6085
    HIV-1 Tat Recruits HDM2 E3 Ligase To Target IRF-1 for Ubiquitination and Proteasomal Degradation
    “... to accelerate IRF-1 proteasome-mediated degradation, resulting in a quenching of IRF-1 transcriptional activity...”
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  6. 6086
    NAD+ biosynthesis ameliorates a zebrafish model of muscular dystrophy.
    “... microenvironment. Cell-matrix adhesions are exquisite sensors of physiological conditions and mediate responses...”
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  7. 6087
    A modular library of small molecule signals regulates social behaviors in Caenorhabditis elegans.
    “... is required for mediating attraction to indole ascarosides instead of the RMG interneurons, which previous...”
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  8. 6088
    HIF-VEGF pathways are critical for chronic otitis media in Junbo and Jeff mouse mutants.
    “... investigated the occurrence of hypoxia and hypoxia-inducible factor (HIF) mediated responses in Junbo and Jeff...”
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  9. 6089
    NF-κB hyper-activation by HTLV-1 tax induces cellular senescence, but can be alleviated by the viral anti-sense protein HBZ.
    “... that p21(CIP1/WAF1)-/p27(KIP1)-mediated senescence constitutes a checkpoint against IKK/NF-κB hyper...”
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  10. 6090
    Glycosaminoglycans and sialylated glycans sequentially facilitate Merkel cell polyomavirus infectious entry.
    “... lines deficient in GAG biosynthesis, we found that N-sulfated and/or 6-O-sulfated forms of HS mediate...”
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  11. 6091
    Enterohemorrhagic Escherichia coli hemolysin employs outer membrane vesicles to target mitochondria and cause endothelial and epithelial apoptosis.
    “... resulting from toxin-mediated microvascular endothelial injury. EHEC hemolysin (EHEC-Hly), a member...”
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  12. 6092
    Juxtamembrane shedding of Plasmodium falciparum AMA1 is sequence independent and essential, and helps evade invasion-inhibitory antibodies.
    “... of PfSUB2-mediated shedding of episomally-expressed PfAMA1 revealed that the position of cleavage...”
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  13. 6093
    Inhibition of Viral Pathogenesis and Promotion of the Septic Shock Response to Bacterial Infection by IRF-3 Are Regulated by the Acetylation and Phosphorylation of Its Coactivators
    “..., it mediates the deleterious septic shock response to bacterial infection. The critical transcription factor...”
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  14. 6094
    Distinct Immunoglobulin Fc Glycosylation Patterns Are Associated with Disease Nonprogression and Broadly Neutralizing Antibody Responses in Children with HIV Infection
    “... adults, but little is known about the underlying mechanisms or the potential role of Fc-mediated effector...”
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  15. 6095
    Biochemical characterization and evaluation of a Brugia malayi small heat shock protein as a vaccine against lymphatic filariasis.
    “... exhibited by the parasite, Interleukin 10 (IL-10) productions and IL-10 mediated immune suppression has...”
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  16. 6096
    Glucose and NAADP trigger elementary intracellular β-cell Ca2+ signals
    “... (IP3) receptor mediated blips, and ryanodine receptor mediated quarks. We propose that a mechanism...”
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  17. 6097
    BKM120 sensitizes BRCA-proficient triple negative breast cancer cells to olaparib through regulating FOXM1 and Exo1 expression
    “... have reported that PI3K inhibition induced the defect of homologous recombination (HR) mediated repair...”
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  18. 6098
    Cationic liposomes promote antigen cross-presentation in dendritic cells by alkalizing the lysosomal pH and limiting the degradation of antigens
    por Gao J, Ochyl LJ, Yang E, Moon JJ
    Publicado 2017
    “... molecules to antigen-presenting cells (APCs), and mediate cellular uptake of vaccine components. CLs...”
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  19. 6099
    Child maltreatment and incident mental disorders in middle and older ages: a retrospective UK Biobank cohort study
    “... as the potential mediators and moderators. Methods: This is a retrospective cohort study of 56,082 participants...”
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  20. 6100
    Folate-conjugated boron nitride nanospheres for targeted delivery of anticancer drug
    por Feng S, Zhang H, Yan T, Huang D, Zhi C, Nakanishi H, Gao XD
    Publicado 2016
    “... drug delivery system based on folate-conjugated BN nanospheres (BNNS) with receptor-mediated targeting...”
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