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  1. 6121
    Global kinome profiling reveals DYRK1A as critical activator of the human mitochondrial import machinery
    “...Mitochondrial protein import is mediated by the translocase of the outer membrane (TOM), through...”
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  2. 6122
    Distinct mechanisms of the human mitoribosome recycling and antibiotic resistance
    “... with mitochondria-specific factors mediating mitoribosome recycling, RRFmt and EF-G2mt, offer insight...”
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  3. 6123
    Structural mechanism of laminin recognition by integrin
    “...Recognition of laminin by integrin receptors mediates epithelial cell adhesion to basement membrane...”
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  4. 6124
    Contraction of basal filopodia controls periodic feather branching via Notch and FGF signaling
    “... is unclear. Here, the authors show that there is a coordinated change in cell shape and adherence, mediated...”
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  5. 6125
    Resolving kinetic intermediates during the regulated assembly and disassembly of fusion pores
    “...SNAREs mediate the formation of a fusion pore during exocytosis which connects the lumen of a...”
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  6. 6126
    YTHDF2 destabilizes m6A-containing RNA through direct recruitment of the CCR4–NOT deadenylase complex
    “... the authors show that this decreased m6A RNA stability is mediated by direct recruitment of the CCR4...”
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  7. 6127
    Structural basis of synaptic vesicle assembly promoted by α-synuclein
    “... the nature and molecular mechanism of α-synuclein-mediated synaptic vesicle clustering....”
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  8. 6128
    Controlling protein activity by dynamic recruitment on a supramolecular polymer platform
    “... the dynamics of supramolecular polymers with the programmability of DNA-mediated protein recruitment....”
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  9. 6129
    Cytoglobin regulates blood pressure and vascular tone through nitric oxide metabolism in the vascular wall
    “... have reduced blood pressure and are less sensitive to angiotensin-mediated hypertension....”
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  10. 6130
    Regulation of Drosophila hematopoietic sites by Activin-β from active sensory neurons
    “... cells (hemocytes) to survive and proliferate, but how this is mediated is unclear. Here, the authors...”
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  11. 6131
    Mixed Weyl semimetals and low-dissipation magnetization control in insulators by spin–orbit torques
    “... spintronics. Here, the authors propose an electrically induced topological phase transition mediated by spin...”
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  12. 6132
    Increased autophagy in EphrinB2-deficient osteocytes is associated with elevated secondary mineralization and brittle bone
    “...Osteoblasts mediate bone formation, and their differentiation requires expression of EphrinB2. Here...”
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  13. 6133
    Quantifying protein dynamics and stability in a living organism
    “... are performed in cell culture. Here the authors combine meganuclease-mediated transformation and fluorescence...”
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  14. 6134
    Organic–inorganic supramolecular solid catalyst boosts organic reactions in water
    “...Coordination polymers and metal-organic frameworks are appealing synthetic hosts for mediating...”
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  15. 6135
    Endophilin-A2 dependent VEGFR2 endocytosis promotes sprouting angiogenesis
    “.... Here Genet et al. show that endophilin A2 regulates these processes by mediating clathrin-independent...”
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  16. 6136
    Investigation of F-BAR domain PACSIN proteins uncovers membrane tubulation function in cilia assembly and transport
    “...PACSIN proteins are known to mediate membrane tubulation. Here the authors show that PACSIN...”
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  17. 6137
    Targeting EZH2 histone methyltransferase activity alleviates experimental intestinal inflammation
    “...EZH2-mediated methylatation of histone 3 is essential for immune regulation. Here, the authors show...”
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  18. 6138
    A neural circuit encoding mating states tunes defensive behavior in Drosophila
    “... flies change the defensive response during courtship and after mating. This switch is mediated...”
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  19. 6139
    Clathrin-adaptor ratio and membrane tension regulate the flat-to-curved transition of the clathrin coat during endocytosis
    “...The sequence of structural and molecular events during clathrin-mediated endocytosis is unclear...”
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  20. 6140
    MicroRNA regulation of endothelial TREX1 reprograms the tumour microenvironment
    “... angiogenesis and leads to the secretion of proinflammatory mediators that reduce tumour growth....”
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