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  1. 6221
    The persistence potential of transferable plasmids
    por Teng Wang, Lingchong You
    Publicado 2020
    “...Conjugative plasmids mediate the spread and maintenance of diverse traits in microbial communities...”
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  2. 6222
    Caspase-1 initiates apoptosis in the absence of gasdermin D
    “...In inflammasomes, caspase-1 activation leads to pyroptosis mediated by gasdermin D, but cells...”
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  3. 6223
    Precocious centriole disengagement and centrosome fragmentation induced by mitotic delay
    “... and centriole disengagement and that spindle bipolarity is ensured by HSET-mediated spindle pole clustering....”
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  4. 6224
    A protein interaction mechanism for suppressing the mechanosensitive Piezo channels
    “...) and give mechanistic insights into mechanogating and SERCA2-mediated regulation of Piezo1....”
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  5. 6225
    Experimental violation of local causality in a quantum network
    “... correlations are mediated by independent sources, a realistic feature in future quantum networks....”
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  6. 6226
    Live-cell imaging of circadian clock protein dynamics in CRISPR-generated knock-in cells
    “... use CRISPR gene editing mediated knock-in to fluorescently tag Per2 and Cry1, and study cellular...”
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  7. 6227
    Chemical synthesis of glycans up to a 128-mer relevant to the O-antigen of Bacteroides vulgatus
    “...Glycans are abundant biomolecules that mediate essential biological processes, but their chemical...”
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  8. 6228
    Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer’s disease model
    “... formation and that Aβ-induced changes in neuronal gene expression are microglia-mediated....”
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  9. 6229
    Regulation of mycobacterial infection by macrophage Gch1 and tetrahydrobiopterin
    “... macrophage Gch1 and tetrahydrobiopterin mediate NO-independent control of Mycobacterial infection....”
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  10. 6230
    Mesopontine cholinergic inputs to midbrain dopamine neurons drive stress-induced depressive-like behaviors
    “... intrinsic plasticity of VTA DA neurons to mediate stress-induced depressive-like behaviors....”
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  11. 6231
    Separating mitochondrial protein assembly and endoplasmic reticulum tethering by selective coupling of Mdm10
    “... this protein interacts with SAM and EMRES, showing that the SAM-mediated protein machinery is independent...”
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  12. 6232
    BMP-dependent synaptic development requires Abi-Abl-Rac signaling of BMP receptor macropinocytosis
    “..., the authors show that Abi-mediated macropinocytosis of BMP receptors in Drosophila larva and contributes...”
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  13. 6233
    Essential omega-3 fatty acids tune microglial phagocytosis of synaptic elements in the mouse developing brain
    “..., the authors show that maternal omega-3 fatty acids deficiency results in altered microglia-mediated...”
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  14. 6234
    A retinoraphe projection regulates serotonergic activity and looming-evoked defensive behaviour
    “... that these RGCs mediate looming-evoked defensive behaviours in mice....”
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  15. 6235
    Nuclear lamin A/C harnesses the perinuclear apical actin cables to protect nuclear morphology
    “..., the authors show that the nuclear lamina protein lamin A/C mediates the formation of the actin cap in response...”
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  16. 6236
    Hepcidin is regulated by promoter-associated histone acetylation and HDAC3
    “.... Here, Pasricha et al. demonstrate that the hepcidin-chromatin locus displays HDAC3-mediated reversible...”
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  17. 6237
    Multiple truncated isoforms of MAVS prevent its spontaneous aggregation in antiviral innate immune signalling
    “... can prevent spontaneous aggregation and degradation in cells to sustain MAVS-mediated immune...”
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  18. 6238
    Dynamics of lineage commitment revealed by single-cell transcriptomics of differentiating embryonic stem cells
    “... into retinoic acid-mediated differentiation using single cell transcriptomics with high temporal resolution....”
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  19. 6239
    Requirement for p62 acetylation in the aggregation of ubiquitylated proteins under nutrient stress
    “...The autophagy receptor p62 mediates the assembly and removal of ubiquitylated protein aggregates...”
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  20. 6240
    Human adaptation and population differentiation in the light of ancient genomes
    “... and Europeans mediated local adaptation in European populations, and were mostly contributed by ancient hunter...”
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